Dr Aled Bryant

Research Highlights

1. Bryant, A., Menzies, G., Scott, L., Spencer-Harty, S., Davies, L., Smith, R., Jones, R., Thornton, C., Jones, R., Thornton, C., Bryant, A. 2017 Human gestation-associated tissues express functional cytosolic nucleic acid sensing pattern recognition receptors Clinical & Experimental Immunology

   https://cronfa.swan.ac.uk/Record/cronfa32814 doi: 10.1111/cei.12960
2. Bryant, A., Thornton, C., Bryant, A. 2012 Cytokines and the Innate Immune Response at the Materno-Fetal Interface (Ed.), Recent Advances in Research on the Human Placenta InTech

   https://cronfa.swan.ac.uk/Record/cronfa20924 doi: 10.5772/33219

   Cytokines and the Innate Immune Response at the Materno-Fetal Interface
3. Thornton, C., Jones, R., Bryant, A. 2011 Inflammation, Obesity, and Neuromodulation in Pregnancy and Fetal Development Advances in Neuroimmune Biology 1 2 193 203

   https://cronfa.swan.ac.uk/Record/cronfa12678 doi: 10.3233/NIB-2011-015

   http://iospress.metapress.com/content/xm2k364n99347t67/?p=b56bc6f21c9e4e298f04f07aa7f3b7d6&pi=7
4. Jones, N., Piasecka, J., Bryant, A., Jones, R., Skibinski, D., Francis, N., Thornton, C., Skibinski, D., Jones, R., Thornton, C., Bryant, A., Jones, N. 2015 Bioenergetic analysis of human peripheral blood mononuclear cells Clinical & Experimental Immunology 182 1 69 80

   https://cronfa.swan.ac.uk/Record/cronfa23517 doi: 10.1111/cei.12662
5. Patni, S., Bryant, A., Wynen, L., Seager, A., Morgan, G., Thornton, C. 2015 Functional activity but not gene expression of toll-like receptors is decreased in the preterm versus term human placenta Placenta 36 9 1031 1038

   https://cronfa.swan.ac.uk/Record/cronfa23518 doi: 10.1016/j.placenta.2015.06.017
6. Bryant, A., Spencer-Harty, S., Owens, S., Jones, R., Thornton, C., Owens, S. 2017 Interleukin 4 and interleukin 13 downregulate the lipopolysaccharide-mediated inflammatory response by human gestation-associated tissues† Biology of Reproduction 96 3 576 586

   https://cronfa.swan.ac.uk/Record/cronfa31647 doi: 10.1095/biolreprod.116.145680
7. Scott, L., Bryant, A., Rees, A., Down, B., Jones, R., Thornton, C. 2017 Production and regulation of interleukin-1 family cytokines at the materno-fetal interface Cytokine 99 194 202

   https://cronfa.swan.ac.uk/Record/cronfa34588 doi: 10.1016/j.cyto.2017.07.005
8. Bryant, A., Bevan, R., Spencer-Harty, S., Scott, L., Jones, R., Thornton, C. 2017 Expression and function of NOD-like receptors by human term gestation-associated tissues Placenta 58 25 32

   https://cronfa.swan.ac.uk/Record/cronfa34833 doi: 10.1016/j.placenta.2017.07.017

All Research

• PM-003 Introduction to Molecular Biology

  This module will provide the learner with an introduction to molecular biology, classification of species and its applications in medical science. The concept of evolution and sexual reproduction and development will also be covered, and the processes of inheritance and genetic variation, particularly with regard to evolution and natural selection. This module will be supported by a practical session and essay with academic support on a topic relevant to the medical applications of molecular biology.

• PM-120 Skills for Geneticists I

  This module is designed to develop the skills required for students of genetics and medical genetics. Students will meet with tutors and be given a series of assignments designed to develop skills in key areas such as essay writing, presentations and general numeracy. Joint sessions will cover generic skills such as internet searching for scientific sources, referencing and plagiarism.

• PM-132C Bioleg Celloedd Ewcaryotig

  Bydd y modiwl hwn yn darparu cyflwyniad bras i gysyniadau sylfaenol ym maes bioleg celloedd Ewcaryotig, gan ymchwilio i darddiad y gell, strwythur y gell a chelloedd arbenigol a chelloedd mewn clefyd. Bydd ffocws cyffredinol ar gelloedd dynol drwy gydol y modiwl, gan gyfeirio at organebau eraill yn ôl yr angen. Bydd myfyrwyr yn cael profiad ymarferol o nodi celloedd, gwahaniaethu rhwng gwahanol gelloedd dynol a rhywogaethau o anifeiliaid.

• PM-141 Human Physiology II

  This module aims to provide students with further understanding of human physiology through studies on systems physiology including the endocrine, renal, blood, digestive/metabolism and reproductive system. The module will equally describe how malfunction of physiological systems gives rise to disease, using specific examples to enable students to appreciate the relationship between physiology/anatomy and medicine. Fundamental principles of physiology will be illustrated with appropriate clinical examples and during practical assignments.

• PM-259 Contemporary themes and techniques in medical sciences

  This module aims to give students an overview of current and emerging themes in medical sciences, both from clinical and laboratory perspectives. This will cover topics generating high media interest, such as the zika virus and alternative methods of transplantation as well as new laboratory techniques. In addition, the module will be supported by two practical classes for which students will be required to conduct mini-projects based around the identification of patient samples and how these are presented as research cases. The module will also involve a one-day "conference", during which students will present data while experiencing a research conference atmosphere.

• PM-334 Biochemistry Literature Review and Communication

  Students will acquire a detailed knowledge of one topical research area of key importance to their particular degree scheme.

• PM-344 Capstone Project

  The aim of this module is to provide a capstone experience to students¿ learning, through participating in their own enquiry-based research project. Depending on the student's employability strand within the programme, the project may be laboratory, data, or education-based, but it will always involve a research question that is drawn from the literature, focused on a topic relevant to medical science. It will ask a novel research question and involve the critical analysis of research findings. Students will refine their oral and written communication skills to a graduate level through creating an introductory presentation on the project background, and a written dissertation and oral presentation on their research conclusions.

• PM-352 Reproductive Biology and Medicine

  This module is designed to provide students with knowledge of the biochemistry, physiology and pathology of human pregnancy, fetal development, parturition and menopause. Particular focus will be given to fertility treatments and pharmacological interventions of menopause. Lectures will cover a recap of endocrinology of reproduction, and provide details of assisted reproductive technologies. Lectures will be supported by case studies which include current clinical approaches used to treat infertility and menopause.