Dr Arron Lacey

Research Highlights

1. Protty, M., Freeman, P., Aldalati, O., Lacey, A., King, W., Anderson, R., & Smith, D. (2015). SEVERE SYMPTOMATIC AORTIC STENOSIS: MEDICAL TREATMENT VERSUS TRANSCATHETER AORTIC VALVE IMPLANTATION: A REAL WORLD ANALYSIS OF ADMISSION PROFILES, COST, AND MORTALITY USING THE SECURE ANONYMISED INFORMATION LINKAGE (SAIL) DATABANK. Journal of the American College of Cardiology, 65(10), A1867

   https://doi.org/10.1016/S0735-1097(15)61867-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38286
2. Protty, M., Protty, M., Lacey, A., Hayes, J., Hayes, J., Freeman, P., & Freeman, P. (2016). Statins for primary prevention in practice: clinical use in Wales and the NICE guideline effect. British Journal of Clinical Pharmacology, 82(3), 892-894.

   https://doi.org/10.1111/bcp.13014, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38284
3. Protty, M., Lacey, A., Smith, D., Hannoodee, S., & Freeman, P. (2017). Increased morbidity, mortality and length of in-hospital stay for patients with acute coronary syndrome with pre-morbid psychiatric diagnoses. International Journal of Cardiology, 236, 5-8.

   https://doi.org/10.1016/j.ijcard.2017.01.067, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38283
4. Protty, M., Hoskins, H., Lacey, A., Smith, D., Freeman, P., & Lacey, A. (2017). 2189The interplay between Acute Coronary Syndrome and Atrial Fibrillation: Poor outcomes and longer hospital stay in a study of 18,444 patients. In European Heart Journal

   https://doi.org/10.1093/eurheartj/ehx502.2189, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38282
5. King, W., Lacey, A., White, J., Farewell, D., Dunstan, F., & Fone, D. (2017). Equity in healthcare for coronary heart disease, Wales (UK) 2004–2010: A population-based electronic cohort study. PLOS ONE, 12(3), e0172618

   https://doi.org/10.1371/journal.pone.0172618, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38281
6. Protty, M., Lacey, A., Hayes, J., & Freeman, P. (2017). Statins for secondary prevention: clinical use in patients with acute coronary syndrome in Wales. Future Cardiology, 13(2), 137-141.

   https://doi.org/10.2217/fca-2016-0060, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38280
7. Fonferko-Shadrach, B., Lacey, A., White, C., Powell, H., Sawhney, I., Lyons, R., Smith, P., Kerr, M., Rees, M., Pickrell, W., Pickrell, O., & Powell, R. (2017). Validating epilepsy diagnoses in routinely collected data. Seizure, 52, 195-198.

   https://doi.org/10.1016/j.seizure.2017.10.008, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38279
8. Freeman, P., Protty, M., Aldalati, O., Lacey, A., King, W., Anderson, R., & Smith, D. (2016). Severe symptomatic aortic stenosis: medical therapy and transcatheter aortic valve implantation (TAVI)—a real-world retrospective cohort analysis of outcomes and cost-effectiveness using national data. Open Heart, 3(1), e000414

   https://doi.org/10.1136/openhrt-2016-000414, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38278
9. Robson, R., Lacey, A., Luzio, S., Van Woerden, H., Heaven, M., Wani, M., Halcox, J., Castilla-Guerra, L., Dawson, J., Hewitt, J., Lacey, A., Luzio, S., & Halcox, J. (2016). HbA1cmeasurement and relationship to incident stroke. Diabetic Medicine, 33(4), 459-462.

   https://doi.org/10.1111/dme.13057, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38277
10. Taylor, P., Lacey, A., Thayer, D., Draman, M., Tabasum, A., Muller, I., Marsh, L., Poacher, A., Roberts, A., Ludgate, M., Rees, A., Boelaert, K., Rees, A., Chan, S., Lazarus, J., Nelson, S., Vaidya, B., & Okosieme, O. (2016). Controlled Antenatal Thyroid Screening Study; Obstetric Outcomes. In Endocrine Abstracts

    https://doi.org/10.1530/endoabs.44.OC6.3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38276
11. Rodgers, S., Heaven, M., Lacey, A., Poortinga, W., Dunstan, F., Jones, K., Palmer, S., Phillips, C., Smith, R., John, A., Davies, G., Lyons, R., Phillips, C., Davies, G., Rodgers, S., Jones, K., Lacey, A., Lyons, R., & John, A. (2012). Cohort Profile: The Housing Regeneration and Health Study. International Journal of Epidemiology

    https://doi.org/10.1093/ije/dys200, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13811
12. Pickrell, W., Lacey, A., Thomas, R., Smith, P., Rees, M., Rees, M., Lacey, A., & Pickrell, O. (2012). Weight change associated with antiepileptic drugs. Journal of Neurology, Neurosurgery & Psychiatry, 84(7), 796-799.

    https://doi.org/10.1136/jnnp-2012-303688, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13956
13. Pickrell, W., Lacey, A., Thomas, R., Lyons, R., Smith, P., Rees, M., & Pickrell, O. (2013). Trends in the first antiepileptic drug prescribed for epilepsy between 2000 and 2010. Seizure

    https://doi.org/10.1016/j.seizure.2013.09.007, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa16640
14. Pickrell, W., Lacey, A., Bodger, O., Demmler, J., Thomas, R., Lyons, R., Smith, P., Rees, M., Kerr, M., Lacey, A., Bodger, O., Demmler, J., Lyons, R., Rees, M., & Pickrell, O. (2015). Epilepsy and deprivation, a data linkage study. Epilepsia, 56(4), 585-591.

    https://doi.org/10.1111/epi.12942, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa20293
15. Edwards, C., Lacey, A., Anderson, M., & Bodger, O. (2015). 98 Are we seeing more cases of Infective Endocarditis after Nice CG64 Recommended Cessation of the use of Antibiotic Prophylaxis? The Welsh Experience. Heart, 101(Suppl 4), A56-A57.

    https://doi.org/10.1136/heartjnl-2015-308066.98, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa24754
16. Jones, K., Lacey, A., Perkins, B., & Rees, M. (2017). Data safe havens to combine health and genomic data: benefits and challenges. In International Journal of Population Data ScienceSwansea University.

    https://doi.org/10.23889/ijpds.v1i1.348, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa34914
17. Lacey, A., Fonferko-Shadrach, B., Lyons, R., Kerr, M., Ford, D., Rees, M., & Pickrell, O. (2017). Obtaining structured clinical data from unstructured data using natural language processing software. International Journal of Population Data Science, 1(1)

    https://doi.org/10.23889/ijpds.v1i1.381, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa37094
18. Lacey, A., Lyons, J., Akbari, A., Turner, S., Walters, A., Fonferko-Shadrach, B., Pickrell, O., Rees, M., Lyons, R., Ford, D., & Middleton, R. (2017). Codifying unstructured data: A Natural Language Processing approach to extract rich data from clinical letters. International Journal for Population Data Science, 1(1)

    https://doi.org/10.23889/ijpds.v1i1.354, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa39437
19. Harris, D., Lacey, A., Akbari, A., Obaid, D., Smith, D., Jenkins, G., Barry, J., Gravenor, M., & Halcox, J. (2019). Early Discontinuation of P2Y12 Antagonists and Adverse Clinical Events Post–Percutaneous Coronary Intervention: A Hospital and Primary Care Linked Cohort. Journal of the American Heart Association, 8(21), A74

    https://doi.org/10.1161/jaha.119.012812, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa40257
20. Fonferko-Shadrach, B., Lacey, A., Akbari, A., Ellwood-Thompson, S., Ford, D., Lyons, R., Rees, M., & Pickrell, O. (2018). Using natural language processing to extract structured epilepsy data from unstructured clinic letters. International Journal of Population Data Science, 3(4)

    https://doi.org/10.23889/ijpds.v3i4.699, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa44398

    http://dx.doi.org/10.23889/ijpds.v3i4.699
21. Jones, K., Daniels, H., Heys, S., Lacey, A., & Ford, D. (2020). Toward a Risk-Utility Data Governance Framework for Research Using Genomic and Phenotypic Data in Safe Havens: Multifaceted Review. Journal of Medical Internet Research, 22(5), e16346

    https://doi.org/10.2196/16346, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53556
22. Daniels, H., Lacey, A., Akbari, A., Powell, R., & Pickrell, O. (2019). Epilepsy Mortality in Wales: 2005-2017. In International Journal of Population Data ScienceSwansea University.

    https://doi.org/10.23889/ijpds.v4i3.1277, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53657
23. Orayj, K., Lacey, A., Akbari, A., Smith, M., Pickrell, O., & Lane, E. (2019). Association between levodopa and ischemic heart disease. In International Journal of Population Data ScienceSwansea University.

    https://doi.org/10.23889/ijpds.v4i3.1172, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53661
24. Torabi, F., Lacey, A., Akbari, A., Harris, D., Lyons, R., Halcox, J., & Gravenor, M. (2020). Machine learning approaches in for prediction of 1-year risk of major bleeding events in anticoagulated atrial fibrillation patients with atrial fibrillation in Wales.. In ESC Heart & Stroke 2020

    https://doi.org/10.13140/RG.2.2.14854.11840, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53813

    https://escheart-stroke2020.org/programme/
25. Harris, D., Lacey, A., Akbari, A., Torabi, F., Smith, D., Jenkins, G., Obaid, D., Chase, A., Gravenor, M., Halcox, J., & Torabi, F. (2020). Achievement of European guideline-recommended lipid levels post-percutaneous coronary intervention: A population-level observational cohort study. European Journal of Preventive Cardiology, 204748732091411

    https://doi.org/10.1177/2047487320914115, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53918
26. Gibson, J., Dobbs, T., Kouzaris, L., Lacey, A., Ellwood-Thompson, S., Akbari, A., Hutchings, H., Lineaweaver, W., Lyons, R., & Whitaker, I. (2021). Making the Most of Big Data in Plastic Surgery. Annals of Plastic Surgery, 86(3), 351-358.

    https://doi.org/10.1097/sap.0000000000002434, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53972
27. Harris, D., Lacey, A., Akbari, A., Gravenor, M., & Halcox, J. (2018). EARLY DISCONTINUATION OF P2Y12 ANTAGONISTS AND ADVERSE CLINICAL OUTCOMES POST PERCUTANEOUS CORONARY INTERVENTION. Journal of the American College of Cardiology, 71(11), A74

    https://doi.org/10.1016/s0735-1097(18)30615-6, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54252
28. Harris, D., Lacey, A., Akbari, A., Gravenor, M., & Halcox, J. (2018). Discontinuation of Statins and Adverse Clinical Outcomes Post Percutaneous Coronary Intervention. In Circulation

    SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54258

    https://www.ahajournals.org/doi/10.1161/circ.138.suppl_1.14994
29. Kansu, B., Pickrell, O., Lacey, A., Edwards, F., Samolia, G., Rees, M., Elwes, R., Hatfield, R., Gray, W., & Hamandi, K. (2020). Long-term outcomes after epilepsy surgery, a retrospective cohort study linking patient-reported outcomes and routine healthcare data. Epilepsy & Behavior, 111, 107196

    https://doi.org/10.1016/j.yebeh.2020.107196, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54431
30. Torabi, F., Lee-Lane, E., Lacey, A., Fonferko-Shadrach, B., Harris, D., Akbari, A., Lyons, R., Rees, M., Sawhney, I., Halcox, J., Powell, R., & Pickrell, O. (2020). A National Level Case-Control Study for Determining Risk of Major Cardiovascular Events in People with Epilepsy. In International Journal of Population Data ScienceSwansea University.

    https://doi.org/10.23889/ijpds.v5i5.1539, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55870
31. Dobbie, S., Strafford, H., Pickrell, O., Fonferko-Shadrach, B., Akbari, A., Ellwood-Thompson, S., & Lacey, A. (2020). Markup: A Web-Based Clinical Annotation Tool with Enhanced Ontology Mapping. In International Journal of Population Data ScienceSwansea University.

    https://doi.org/10.23889/ijpds.v5i5.1634, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55875
32. Miah, L., Strafford, H., Fonferko-Shadrach, B., Hollinghurst, J., Sawhney, I., Hadjikoutis, S., Rees, M., Powell, R., Lacey, A., & Pickrell, O. (2021). Incidence, Prevalence, and Health Care Outcomes in Idiopathic Intracranial Hypertension. Neurology, 96(8), e1251-e1261.

    https://doi.org/10.1212/wnl.0000000000011463, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56133
33. Orayj, K., Akbari, A., Lacey, A., Smith, M., Pickrell, O., & Lane, E. (2021). Factors affecting the choice of first-line therapy in Parkinson’s disease patients in Wales: A population-based study. Saudi Pharmaceutical Journal, 29(2), 206-212.

    https://doi.org/10.1016/j.jsps.2021.01.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56151
34. Lee‐Lane, E., Torabi, F., Lacey, A., Fonferko-Shadrach, B., Harris, D., Akbari, A., Lyons, R., Rees, M., Sawhney, I., Halcox, J., Powell, R., & Pickrell, O. (2021). Epilepsy, antiepileptic drugs, and the risk of major cardiovascular events. Epilepsia, 62(7), 1604-1616.

    https://doi.org/10.1111/epi.16930, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56988
35. Wang, Q., Laramee, B., Lacey, A., & Pickrell, O. (2021). LetterVis: a letter-space view of clinic letters. The Visual Computer, 37(9-11), 2643-2656.

    https://doi.org/10.1007/s00371-021-02171-w, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57136
36. Dobbie, S., Strafford, H., Pickrell, O., Fonferko-Shadrach, B., Jones, C., Akbari, A., Ellwood-Thompson, S., & Lacey, A. (2021). Markup: A Web-Based Annotation Tool Powered by Active Learning. Frontiers in Digital Health, 3

    https://doi.org/10.3389/fdgth.2021.598916, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57479
37. Daniels, H., Lacey, A., Mikadze, D., Akbari, A., Fonferko-Shadrach, B., Hollinghurst, J., Lyons, R., Rees, M., Sawhney, I., Powell, R., Kerr, M., & Pickrell, O. (2022). Epilepsy mortality in Wales during COVID-19. Seizure - European Journal of Epilepsy, 94, 39-42.

    https://doi.org/10.1016/j.seizure.2021.11.017, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa58860
38. Ellins, L., Harris, D., Lacey, A., Akbari, A., Torabi, F., Smith, D., Jenkins, G., Obaid, D., Chase, A., John, A., Gravenor, M., & Halcox, J. (2022). Achievement of European Society of Cardiology/European Atherosclerosis Society lipid targets in very high-risk patients: Influence of depression and sex. PLOS ONE, 17(2), e0264529

    https://doi.org/10.1371/journal.pone.0264529, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59420
39. Daniels, H., Lacey, A., Akbari, A., Fonferko-Shadrach, B., Hollinghurst, J., Rees, M., Sawhney, I., Powell, H., Kerr, M., & Pickrell, O. (2022). 146  Epilepsy, deprivation and mortality in Wales 2005–2017

    https://doi.org/10.1136/jnnp-2022-abn.177, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60130
40. Ali, S., Strafford, H., Dobbs, T., Fonferko-Shadrach, B., Lacey, A., Pickrell, O., Hutchings, H., & Whitaker, I. (2022). Development and validation of an automated basal cell carcinoma histopathology information extraction system using natural language processing. Frontiers in Surgery, 9

    https://doi.org/10.3389/fsurg.2022.870494, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60444
41. Ali, S., Dobbs, T., Jovic, M., Strafford, H., Fonferko-Shadrach, B., Lacey, A., Williams, N., Pickrell, O., Hutchings, H., & Whitaker, I. (2023). Validating a novel natural language processing pathway for automated quality assurance in surgical oncology: incomplete excision rates of 34 955 basal cell carcinomas. British Journal of Surgery, 110(9), 1072-1075.

    https://doi.org/10.1093/bjs/znad055, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63002

    http://dx.doi.org/10.1093/bjs/znad055
42. Strafford, H., Lacey, A., Hollinghurst, J., Akbari, A., Watkins, A., Paterson, J., Jennings, D., Lyons, R., Powell, R., Kerr, M., Chin, R., & Pickrell, O. (2023). COVID-19 vaccination uptake in people with epilepsy in wales. Seizure, 108, 49-52.

    https://doi.org/10.1016/j.seizure.2023.04.006, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63099

    http://dx.doi.org/10.1016/j.seizure.2023.04.006
43. Fonferko-Shadrach, B., Lacey, A., Strafford, H., Jones, C., Baker, M., Powell, R., Akbari, A., Lyons, R., Ford, D., Ellwood-Thompson, S., Jones, K., Chung, S., Pickrell, O., & Rees, M. (2023). Genetic influences on epilepsy outcomes: a whole‐exome sequencing and healthcare records data linkage study. Epilepsia

    https://doi.org/10.1111/epi.17766, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa64175

    http://dx.doi.org/10.1111/epi.17766
44. Ali, S., Dobbs, T., Jovic, M., Strafford, H., Lacey, A., Williams, N., Pickrell, O., Hutchings, H., & Whitaker, I. (2024). Revisiting basal cell carcinoma clinical margins: Leveraging natural language processing and multivariate analysis with updated Royal College of Pathologists histological reporting standards. Journal of Plastic, Reconstructive and Aesthetic Surgery, 88, 443-451.

    https://doi.org/10.1016/j.bjps.2023.10.106, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa64779
45. Torabi, F., Harris, D., Lacey, A., Akbari, A., Gravenor, M., Halcox, J., & Harris, D. (2023). External Validation of HASBLED and ORBIT bleeding risk scores in Wales-AF population. European Heart Journal, 44(Supplement_2)

    https://doi.org/10.1093/eurheartj/ehad655.2450, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65171

    http://dx.doi.org/10.1093/eurheartj/ehad655.2450
46. Ali, S., Dobbs, T., Tarafdar, A., Strafford, H., Fonferko-Shadrach, B., Lacey, A., Pickrell, O., Hutchings, H., & Whitaker, I. (2024). Natural language processing to automate a web-based model of care and modernize skin cancer multidisciplinary team meetings. British Journal of Surgery, 111(1)

    https://doi.org/10.1093/bjs/znad347, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65543
47. Strafford, H., Hollinghurst, J., Lacey, A., Akbari, A., Watkins, A., Paterson, J., Jennings, D., Lyons, R., Powell, R., Kerr, M., Chin, R., & Pickrell, O. (2024). Epilepsy and the risk of COVID-19-related hospitalization and death: A population study. Epilepsia, 0

    https://doi.org/10.1111/epi.17910, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65804
48. Strafford, H., Hollinghurst, J., Lacey, A., Akbari, A., Watkins, A., Paterson, J., Jennings, D., Lyons, R., Powell, R., Kerr, M., Chin, R., & Pickrell, O. (2024). Health care utilization and mortality for people with epilepsy during COVID‐19: A population study. Epilepsia, 0

    https://doi.org/10.1111/epi.17920, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65805

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