Professor Steve Bain

Professor in Medicine(Diabetes), Biomedical Sciences

+44 (0) 1792 602205

s.c.bain@swansea.ac.uk

Office - 115
Ground Floor
Grove Building
Singleton Campus

Available For Postgraduate Supervision

Research Links

https://orcid.org/0000-0001-8519-4964

About

Professor Steve Bain is Assistant Medical Director for Research & Development for Swansea Bay University Health Board and Clinical Director of the Diabetes Research Unit in Swansea University.

After undergraduate training at St John's College, Cambridge, he was clinically trained at King's College Hospital, London. Qualifying in 1983, he held junior appointments in London, East Midlands, and West Midlands. His research centred on the genetics of type 1 diabetes, and he was granted a Medical Research Council Lecturership. In 1993, he became a Senior Lecturer/Honorary Consultant Physician at Birmingham Heartlands Hospital, with promotion to Reader in Diabetic Medicine in 1998. Professor Bain became a Fellow of the Royal College of Physicians, UK, in 1996 and was appointed to a newly created Chair in Medicine (Diabetes) at Swansea University in 2005. His clinical interests include the genetics of diabetic nephropathy, new therapies for diabetes and the provision of diabetes services within the community. He has been Chief Investigator for several multi-centre trials investigating novel therapies for diabetes.

As a result of his genetics background, Professor Bain became a member of the inaugural West Midlands Multicentre Research Ethics Committee (MREC) and joined the UK Human Genetics Commission. From 2003-2008 he was HGC’s nomination on the National DNA Database Strategy Board and led the HGC report on DNA testing in 2009. In 2007 he was invited to sit on the newly formed National DNA Database Ethics Group, established by the Secretary of State for the Home Department. Professor Bain is Diabetes Lead Clinician for Swansea Bay University Health Board, a member of the Wales Diabetes & Endocrine Society (WEDS) executive committee and chaired the Specialist Training Committee for Diabetes & Endocrinology for Wales until 2016. He also chairs the Board which oversees the ILS Joint Clinical Research Facility, the premier clinical research institute in Wales.

Areas Of Expertise

Clinical management type 2 diabetes
Clinical management type 1 diabetes
Cardiovascular outcome trials of type 2 diabetes
Modern therapies for diabetes
Research & Development in the NHS
Peer review of scientific manuscripts and grant applications

Career Highlights

Teaching Interests

Diabetes Practice Masters, Swansea University – Course Clinical Lead

PMDM01 Diabetes Basics

PMDM05 Diabetes Management II

PMDM101 Diabetic Practice

PMZM17 Diabetes Management II

PMZM18 Diabetic Practice

PM-356 The Sweet Sickness: Advances in Diabetes and Related Disorders

Research Award Highlights Collaborations

Publications

Research Highlights

Amer, S. & Bain, S. (n.d.) Sleep disturbance due to hand discomfort. Diabetic Medicine
https://doi.org/10.1111/dme.15330, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65983
http://dx.doi.org/10.1111/dme.15330
Seidu, S., Alabraba, V., Davies, S., Newland-Jones, P., Fernando, K., Bain, S., Diggle, J., Evans, M., James, J., Kanumilli, N., Milne, N., Viljoen, A., Wheeler, D., & Wilding, J. (n.d.) SGLT2 Inhibitors – The New Standard of Care for Cardiovascular, Renal and Metabolic Protection in Type 2 Diabetes: A Narrative Review. Diabetes Therapy
https://doi.org/10.1007/s13300-024-01550-5, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65982
http://dx.doi.org/10.1007/s13300-024-01550-5
Chowdhury, S., Sadouki, F., Collins, E., Keen, F., Bhagi, R., Lim, Y., Cozma, S., & Bain, S. (n.d.) Real-World Use of Oral and Subcutaneous Semaglutide in Routine Clinical Practice in the UK: A Single-Centre, Retrospective Observational Study. Diabetes Therapy
https://doi.org/10.1007/s13300-024-01551-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65730
http://dx.doi.org/10.1007/s13300-024-01551-4
McCarthy, O., Christensen, M., Kristensen, K., Schmidt, S., Ranjan, A., Bain, S., Bracken, R., & Nørgaard, K. (2023). Automated Insulin Delivery Around Exercise in Adults with Type 1 Diabetes: A Pilot Randomized Controlled Study. Diabetes Technology & Therapeutics, 25(7), 476-484.
https://doi.org/10.1089/dia.2023.0009, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63844
http://dx.doi.org/10.1089/dia.2023.0009
Bain, S., Carstensen, B., Hyveled, L., Seremetis, S., Kreiner, F., Amadid, H., & Clark, A. (2023). Glucagon-like peptide-1 receptor agonist use is associated with lower blood ferritin levels in people with type 2 diabetes and hemochromatosis: a nationwide register-based study. BMJ Open Diabetes Research & Care, 11(3), e003300
https://doi.org/10.1136/bmjdrc-2022-003300, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63949
http://dx.doi.org/10.1136/bmjdrc-2022-003300
Rosenstock, J., Bain, S., Gowda, A., Jódar, E., Liang, B., Lingvay, I., Nishida, T., Trevisan, R., & Mosenzon, O. (2023). Weekly Icodec versus Daily Glargine U100 in Type 2 Diabetes without Previous Insulin. New England Journal of Medicine, 389(4), 297-308.
https://doi.org/10.1056/nejmoa2303208, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63791
http://dx.doi.org/10.1056/nejmoa2303208
Bain, S. & Min, T. (2023). A new class of glucose-lowering therapy for type 2 diabetes: the latest development in the incretin arena. The Lancet, 402(10401)
https://doi.org/10.1016/s0140-6736(23)01182-0, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63790
http://dx.doi.org/10.1016/s0140-6736(23)01182-0
Connolly, D., Zaman, A., Capps, N., Bain, S., & Fernando, K. (2023). Assessing opinion on lower LDL-cholesterol lowering, and the role of newer lipid-reducing treatment options. British Journal of Cardiology, 30
https://doi.org/10.5837/bjc.2023.014, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63663
Hayes, J., Rafferty, J., Cheung, W., Akbari, A., Thomas, R., Bain, S., Topliss, C., & Stephens, J. (2023). Quantifying the incidence of lower limb amputation in people with and without diabetes in Wales between 2008–2018. Diabetes Epidemiology and Management, 11, 100144
https://doi.org/10.1016/j.deman.2023.100144, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63611
http://dx.doi.org/10.1016/j.deman.2023.100144
Wijewickrama, P., Williams, J., Bain, S., Dasgupta, I., Chowdhury, T., Wahba, M., Frankel, A., Lambie, M., Karalliedde, J., Dasgupta, I., Chowdhury, T., Wahba, M., Frankel, A., & Karalliedde, J. (2023). Narrative Review of Glycemic Management in People With Diabetes on Peritoneal Dialysis. Kidney International Reports, 8(4), 700-714.
https://doi.org/10.1016/j.ekir.2023.01.040, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63333
http://dx.doi.org/10.1016/j.ekir.2023.01.040
Tuttle, K., Bosch-Traberg, H., Cherney, D., Hadjadj, S., Lawson, J., Mosenzon, O., Rasmussen, S., & Bain, S. (2023). Post hoc analysis of SUSTAIN 6 and PIONEER 6 trials suggests that people with type 2 diabetes at high cardiovascular risk treated with semaglutide experience more stable kidney function compared with placebo. Kidney International, 103(4), 772-781.
https://doi.org/10.1016/j.kint.2022.12.028, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63332
http://dx.doi.org/10.1016/j.kint.2022.12.028
Moser, O., Rafferty, J., Eckstein, M., Aziz, F., Bain, S., Bergenstal, R., Sourij, H., Thomas, R., Rafferty, J., & Thomas, B. (2023). Impact of severe hypoglycaemia requiring hospitalization on mortality in people with type 1 diabetes: A national retrospective observational cohort study. Diabetes, Obesity and Metabolism, 25(8), 2243-2254.
https://doi.org/10.1111/dom.15102, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63220
http://dx.doi.org/10.1111/dom.15102
Min, T. & Bain, S. (2023). Emerging drugs for the treatment of type 1 diabetes mellitus: a review of phase 2 clinical trials. Expert Opinion on Emerging Drugs, 28(1), 1-15.
https://doi.org/10.1080/14728214.2023.2188191, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62930
http://dx.doi.org/10.1080/14728214.2023.2188191
Williams, D., Crockett, E., Aye, S., Latheef, M., Chokor, M., Roberts, R., Bain, S., Stephens, J., & Min, T. (2023). Freestyle libre use in people with type 2 diabetes using basal-bolus insulin is associated with improved glycaemic control: A real-world analysis. Primary Care Diabetes, 17(2)
https://doi.org/10.1016/j.pcd.2023.01.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62662
Viljoen, A. & Bain, S. (2023). Glucagon-Like Peptide 1 Therapy: From Discovery to Type 2 Diabetes and Beyond. Endocrinology and Metabolism, 38(1), 25-33.
https://doi.org/10.3803/enm.2022.1642, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62654
Evans, M., Berry, S., Nazeri, A., Malkin, S., Ashley, D., Hunt, B., & Bain, S. (2023). The challenges and pitfalls of incorporating evidence from cardiovascular outcomes trials in health economic modelling of type 2 diabetes. Diabetes, Obesity and Metabolism, 25(3), 639-648.
https://doi.org/10.1111/dom.14917, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62592
Bain, S. (2022). Fat – pharmacological therapies. British Journal of Diabetes, 22(Supplement 1), S59-S61.
https://doi.org/10.15277/bjd.2022.367, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62284
Bain, S. (2022). The place of Glucagon-like 1 peptide receptor agonists (GLP-1RAs) in the new NICE guidelines – what is going on?. British Journal of Diabetes, 22(2), 69-71.
https://doi.org/10.15277/bjd.2022.381, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62283
Williams, D., Staff, M., Bain, S., & Min, T. (2022). Glucagon-like Peptide-1 Receptor Analogues for the Treatment of Obesity. Endocrinology, 18(1), 43
https://doi.org/10.17925/ee.2022.18.1.43, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60990
McCarthy, O., Schmidt, S., Christensen, M., Bain, S., Nørgaard, K., & Bracken, R. (2022). The endocrine pancreas during exercise in people with and without type 1 diabetes: Beyond the beta-cell. Frontiers in Endocrinology, 13
https://doi.org/10.3389/fendo.2022.981723, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa61554
McCarthy, O., Kristensen, K., Christensen, M., Schmidt, S., Ranjan, A., Nicholas, C., Bain, S., Nørgaard, K., & Bracken, R. (2023). Metabolic and physiological responses to graded exercise testing in individuals with type 1 diabetes using insulin pump therapy. Diabetes, Obesity and Metabolism, 25(3)
https://doi.org/10.1111/dom.14938, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62161
Salem, A., Bain, S., & Obaid, D. (2022). Glucagon-like peptide-1 receptor agonists as anti-inflammatory agents: A potential mode of cardiovascular benefits. Atherosclerosis, 352, 83-84.
https://doi.org/10.1016/j.atherosclerosis.2022.05.010, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60290
Evans, M., Morgan, A., Bain, S., Davies, S., Dashora, U., Sinha, S., Seidu, S., Patel, D., Beba, H., & Strain, W. (2022). Defining the Role of SGLT2 Inhibitors in Primary Care: Time to Think Differently. Diabetes Therapy, 13(5), 889-911.
https://doi.org/10.1007/s13300-022-01242-y, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59763
Wilding, J., Evans, M., Fernando, K., Gorriz, J., Cebrian, A., Diggle, J., Hicks, D., James, J., Newland-Jones, P., Ali, A., Bain, S., Porto, A., Patel, D., Viljoen, A., Wheeler, D., & Prato, S. (2022). The Place and Value of Sodium-Glucose Cotransporter 2 Inhibitors in the Evolving Treatment Paradigm for Type 2 Diabetes Mellitus: A Narrative Review. Diabetes Therapy, 13(5), 847-872.
https://doi.org/10.1007/s13300-022-01228-w, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59694
Husain, M., Consoli, A., Remigis, A., Meyer, A., Rasmussen, S., & Bain, S. (2022). Semaglutide reduces cardiovascular events regardless of metformin use: a post hoc subgroup analysis of SUSTAIN 6 and PIONEER 6. Cardiovascular Diabetology, 21(1)
https://doi.org/10.1186/s12933-022-01489-6, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59680
Karalliedde, J., Winocour, P., Chowdhury, T., De, P., Frankel, A., Montero, R., Pokrajac, A., Banerjee, D., Dasgupta, I., Fogarty, D., Sharif, A., Wahba, M., Mark, P., Zac‐Varghese, S., Patel, D., & Bain, S. (2022). Clinical practice guidelines for management of hyperglycaemia in adults with diabetic kidney disease. Diabetic Medicine, 39(4)
https://doi.org/10.1111/dme.14769, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59311
Wylie, T., Morris, A., Robertson, E., Middleton, A., Newbert, C., Andersen, B., Maltese, G., Stocker, R., Weightman, A., Sinclair, A., & Bain, S. (2022). Ageing well with diabetes: A workshop to co‐design research recommendations for improving the diabetes care of older people. Diabetic Medicine, 39(7)
https://doi.org/10.1111/dme.14795, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59310
Banerjee, D., Winocour, P., Chowdhury, T., De, P., Wahba, M., Montero, R., Fogarty, D., Frankel, A., Goldet, G., Karalliedde, J., Mark, P., Patel, D., Pokrajac, A., Sharif, A., Zac-Varghese, S., Bain, S., & Dasgupta, I. (2022). Management of Hypertension in Patients With Diabetic Kidney Disease: Summary of the Joint Association of British Clinical Diabetologists and UK Kidney Association (ABCD-UKKA) Guideline 2021. Kidney International Reports, 7(4), 681-687.
https://doi.org/10.1016/j.ekir.2022.01.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59219
Shaman, A., Bain, S., Bakris, G., Buse, J., Idorn, T., Mahaffey, K., Mann, J., Nauck, M., Rasmussen, S., Rossing, P., Wolthers, B., Zinman, B., & Perkovic, V. (2022). Effect of the Glucagon-Like Peptide-1 Receptor Agonists Semaglutide and Liraglutide on Kidney Outcomes in Patients With Type 2 Diabetes: Pooled Analysis of SUSTAIN 6 and LEADER. Circulation, 145(8), 575-585.
https://doi.org/10.1161/circulationaha.121.055459, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59068
Banerjee, D., Winocour, P., Chowdhury, T., De, P., Wahba, M., Montero, R., Fogarty, D., Frankel, A., Karalliedde, J., Mark, P., Patel, D., Pokrajac, A., Sharif, A., Zac-Varghese, S., Bain, S., Dasgupta, I., & Association), . (2022). Management of hypertension and renin-angiotensin-aldosterone system blockade in adults with diabetic kidney disease: Association of British Clinical Diabetologists and the Renal Association UK guideline update 2021. BMC Nephrology, 23(1)
https://doi.org/10.1186/s12882-021-02587-5, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59060
Evans, M., Morgan, A., Bain, S., Davies, S., Hicks, D., Brown, P., Yousef, Z., Dashora, U., Viljoen, A., Beba, H., & Strain, W. (2022). Meeting the Challenge of Virtual Diabetes Care: A Consensus Viewpoint on the Positioning and Value of Oral Semaglutide in Routine Clinical Practice. Diabetes Therapy, 13(2), 225-240.
https://doi.org/10.1007/s13300-021-01201-z, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59059
Evans, M., Morgan, A., Whyte, M., Hanif, W., Bain, S., Kalra, P., Davies, S., Dashora, U., Yousef, Z., Patel, D., & Strain, W. (2022). New Therapeutic Horizons in Chronic Kidney Disease: The Role of SGLT2 Inhibitors in Clinical Practice. Drugs, 82(2), 97-108.
https://doi.org/10.1007/s40265-021-01655-2, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa58766
Evans, M., Lewis, R., Morgan, A., Whyte, M., Hanif, W., Bain, S., Davies, S., Dashora, U., Yousef, Z., Patel, D., & Strain, W. (2022). A Narrative Review of Chronic Kidney Disease in Clinical Practice: Current Challenges and Future Perspectives. Advances in Therapy, 39(1), 33-43.
https://doi.org/10.1007/s12325-021-01927-z, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa58735
Bain, E. & Bain, S. (2021). Recent developments in GLP‐1RA therapy: A review of the latest evidence of efficacy and safety and differences within the class. Diabetes, Obesity and Metabolism, 23(S3), 30-39.
https://doi.org/10.1111/dom.14487, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa58129
Fernando, K., Bain, S., Holmes, P., Jones, P., & Patel, D. (2021). Glucagon-Like Peptide 1 Receptor Agonist Usage in Type 2 Diabetes in Primary Care for the UK and Beyond: A Narrative Review. Diabetes Therapy, 12(9), 2267-2288.
https://doi.org/10.1007/s13300-021-01116-9, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa58128
Khunti, K., Hertz, C., Husemoen, L., Mocevic, E., Nordsborg, R., Piltoft, J., & Bain, S. (2022). Cardiovascular risk factors early in the course of treatment in people with type 2 diabetes without established cardiovascular disease: A population‐based observational retrospective cohort study. Diabetic Medicine, 39(3)
https://doi.org/10.1111/dme.14697, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57800
McCarthy, O., Pitt, J., ECKSTEIN, M., MOSER, O., Bain, S., & Bracken, R. (2021). Pancreatic β-Cell Function Is Associated with Augmented Counterregulation to In-Exercise Hypoglycemia in Type 1 Diabetes. Medicine & Science in Sports & Exercise, 53(7), 1326-1333.
https://doi.org/10.1249/mss.0000000000002613, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57228
Reed, J., Bain, S., & Kanamarlapudi, V. (2021). A Review of Current Trends with Type 2 Diabetes Epidemiology, Aetiology, Pathogenesis, Treatments and Future Perspectives. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 14, 3567-3602.
https://doi.org/10.2147/dmso.s319895, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57318
Evans, M., Morgan, A., Yousef, Z., Ellis, G., Dashora, U., Patel, D., Brown, P., Hanif, W., Townend, J., Kanumilli, N., Moore, J., Wilding, J., & Bain, S. (2021). Optimising the Heart Failure Treatment Pathway: The Role of SGLT2 Inhibitors. Drugs, 81(11), 1243-1255.
https://doi.org/10.1007/s40265-021-01538-6, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56924
Rafferty, J., Stephens, J., Atkinson, M., Luzio, S., Akbari, A., Gregory, J., Bain, S., Owens, D., & Thomas, B. (2021). A retrospective epidemiological study of Type 1 Diabetes Mellitus in Wales, UK between 2008 and 2018. International Journal of Population Data Science, 6(1)
https://doi.org/10.23889/ijpds.v6i1.1387, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56716
Bain, S., Rickford, A., Black, N., Hamilton, L., Camfield, E., Chamley, M., Hodgkinson, A., & Karalliedde, J. (2021). Delivering joined-up care for people with type 2 diabetes: rationale, challenges and examples. British Journal of Diabetes, 21(1), 89-95.
https://doi.org/10.15277/bjd.2021.294, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56389
Saunders, I. & Bain, S. (2021). A woman with poorly controlled type 1 diabetes and pruritic papules on her buttocks. Diabetic Medicine, 38(8)
https://doi.org/10.1111/dme.14539, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56314
Herrath, M., Bain, S., Bode, B., Clausen, J., Coppieters, K., Gaysina, L., Gumprecht, J., Hansen, T., Mathieu, C., Morales, C., Mosenzon, O., Segel, S., Tsoukas, G., Pieber, T., Ludvik, B., Prager, R., Paulweber, B., Ebenbichler, C., Keymeulen, B...., & Kreiner, F. (2021). Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial. The Lancet Diabetes & Endocrinology, 9(4), 212-224.
https://doi.org/10.1016/s2213-8587(21)00019-x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56262
http://dx.doi.org/10.1016/s2213-8587(21)00019-x
Williams, D., Ruslan, A., Khan, R., Vijayasingam, D., Iqbal, F., Shaikh, A., Lim, J., Chudleigh, R., Peter, R., Udiawar, M., Bain, S., Stephens, J., & Min, T. (2021). Real-World Clinical Experience of Semaglutide in Secondary Care Diabetes: A Retrospective Observational Study. Diabetes Therapy, 12(3), 801-811.
https://doi.org/10.1007/s13300-021-01015-z, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56157
Chowdhury, T., Wahba, M., Mallik, R., Peracha, J., Patel, D., De, P., Fogarty, D., Frankel, A., Karalliedde, J., Mark, P., Montero, R., Pokrajac, A., Zac‐Varghese, S., Bain, S., Dasgupta, I., Banerjee, D., Winocour, P., & Sharif, A. (2021). Association of British Clinical Diabetologists and Renal Association guidelines on the detection and management of diabetes post solid organ transplantation. Diabetic Medicine, 38(6)
https://doi.org/10.1111/dme.14523, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55995
Persson, F., Bain, S., Mosenzon, O., Heerspink, H., Mann, J., Pratley, R., Raz, I., Idorn, T., Rasmussen, S., Scholten, B., & Rossing, P. (2021). Changes in Albuminuria Predict Cardiovascular and Renal Outcomes in Type 2 Diabetes: A Post Hoc Analysis of the LEADER Trial. Diabetes Care, 44(4), 1020-1026.
https://doi.org/10.2337/dc20-1622, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55970
Bain, S., Czernichow, S., Bøgelund, M., Madsen, M., Yssing, C., McMillan, A., Hvid, C., Hettiarachchige, N., & Panton, U. (2021). Costs of COVID-19 pandemic associated with diabetes in Europe: a health care cost model. Current Medical Research and Opinion, 37(1), 27-36.
https://doi.org/10.1080/03007995.2020.1862775, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55911
Min, T. & Bain, S. (2021). The Role of Tirzepatide, Dual GIP and GLP-1 Receptor Agonist, in the Management of Type 2 Diabetes: The SURPASS Clinical Trials. Diabetes Therapy, 12(1), 143-157.
https://doi.org/10.1007/s13300-020-00981-0, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55784
McCarthy, O., Deere, R., Eckstein, M., Pitt, J., Wellman, B., Bain, S., Moser, O., & Bracken, R. (2021). Improved Nocturnal Glycaemia and Reduced Insulin Use Following Clinical Exercise Trial Participation in Individuals With Type 1 Diabetes. Frontiers in Public Health, 8
https://doi.org/10.3389/fpubh.2020.568832, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55783
McCarthy, O., Deere, R., Churm, R., Dunseath, G., Jones, C., Eckstein, M., Williams, D., Hayes, J., Pitt, J., Bain, S., Moser, O., & Bracken, R. (2021). Extent and prevalence of post-exercise and nocturnal hypoglycemia following peri-exercise bolus insulin adjustments in individuals with type 1 diabetes. Nutrition, Metabolism and Cardiovascular Diseases, 31(1), 227-236.
https://doi.org/10.1016/j.numecd.2020.07.043, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55261
McCarthy, O., Pitt, J., Churm, R., Dunseath, G., Jones, C., Bally, L., Nakas, C., Deere, R., Eckstein, M., Bain, S., Moser, O., & Bracken, R. (2020). Metabolomic, hormonal and physiological responses to hypoglycemia versus euglycemia during exercise in adults with type 1 diabetes. BMJ Open Diabetes Research & Care, 8(1)
https://doi.org/10.1136/bmjdrc-2020-001577, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55338
Bain, S. (2020). Lowering of Hemoglobin A1C and Risk of Cardiovascular Outcomes and All-Cause Mortality, A Meta-Regression Analysis [Expert Comment on article published in: Journal of Diabetes and Its Complications 2020 Jul 31;[EPub Ahead of Print], M Fralick, M Colacci, A Odutayo, R Siemieniuk, RJ Glynne]
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55061
https://www.practiceupdate.com/content/lowering-of-hemoglobin-a1c-and-risk-of-cardiovascular-outcomes/104435/65/8/1
Turner, D., Gray, B., Luzio, S., Dunseath, G., Bain, S., Hanley, S., Richards, A., Rhydderch, D., Ayles, M., Kilduff, L., Campbell, M., West, D., & Bracken, R. (2016). Similar magnitude of post-exercise hyperglycemia despite manipulating resistance exercise intensity in type 1 diabetes individuals. Scandinavian Journal of Medicine & Science in Sports, 26(4), 404-412.
https://doi.org/10.1111/sms.12472, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa20927
Verma, S., McGuire, D., Bain, S., Bhatt, D., Leiter, L., Mazer, C., Fries, T., Pratley, R., Rasmussen, S., Vrazic, H., Zinman, B., & Buse, J. (2020). Effects of glucagon-like peptide-1 receptor agonists liraglutide and semaglutide on cardiovascular and renal outcomes across body mass index categories in type 2 diabetes: Results of the LEADER and SUSTAIN 6 trials. Diabetes, Obesity and Metabolism, 22(12), 2487-2492.
https://doi.org/10.1111/dom.14160, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54840
Husain, M., Bain, S., Holst, A., Mark, T., Rasmussen, S., & Lingvay, I. (2020). Effects of semaglutide on risk of cardiovascular events across a continuum of cardiovascular risk: combined post hoc analysis of the SUSTAIN and PIONEER trials. Cardiovascular Diabetology, 19(1)
https://doi.org/10.1186/s12933-020-01106-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54830
Moser, O., Eckstein, M., McCarthy, O., Deere, R., Pitt, J., Williams, D., Hayes, J., Sourij, H., Bain, S., & Bracken, R. (2019). Performance of the Freestyle Libre flash glucose monitoring (flash GM) system in individuals with type 1 diabetes: A secondary outcome analysis of a randomized crossover trial. Diabetes, Obesity and Metabolism, 21(11), 2505-2512.
https://doi.org/10.1111/dom.13835, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51468
Chudleigh, R. & Bain, S. (2020). Efficacy of newer agents in the glycaemic management of patients with type 2 diabetes. Current Medical Research and Opinion, 36(2), 209-211.
https://doi.org/10.1080/03007995.2019.1678344, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52648
Verma, S., Bain, S., Buse, J., Idorn, T., Rasmussen, S., Ørsted, D., & Nauck, M. (2019). Occurence of First and Recurrent Major Adverse Cardiovascular Events With Liraglutide Treatment Among Patients With Type 2 Diabetes and High Risk of Cardiovascular Events. JAMA Cardiology, 4(12), 1214
https://doi.org/10.1001/jamacardio.2019.3080, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52744
Bain, S., Feher, M., Fisher, M., Hex, N., Lee, K., Mahon, J., Russell‐Jones, D., Schou, H., Wilmot, E., & Baxter, M. (2020). A review of the NG17 recommendations for the use of basal insulin in type 1 diabetes. Diabetic Medicine, 37(2), 219-228.
https://doi.org/10.1111/dme.14180, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52764
Bain, S., Hansen, B., Malkin, S., Nuhoho, S., Valentine, W., Chubb, B., Hunt, B., & Capehorn, M. (2020). Oral Semaglutide Versus Empagliflozin, Sitagliptin and Liraglutide in the UK: Long-Term Cost-Effectiveness Analyses Based on the PIONEER Clinical Trial Programme. Diabetes Therapy, 11(1), 259-277.
https://doi.org/10.1007/s13300-019-00736-6, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52765
Bain, S. (2019). Oral Semaglutide and Cardiovascular Outcomes in Type 2 Diabetes. New England Journal of Medicine, 381(21), 2075-2077.
https://doi.org/10.1056/nejmc1913157, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52897
Bain, S., Bakhai, A., Evans, M., Green, A., Menown, I., & Strain, W. (2020). An update to: Pharmacological treatment for type 2 diabetes integrating findings from cardiovascular outcome trials: an expert consensus in the UK. Diabet Med 2019; 36: 1063–1071. Diabetic Medicine, 37(8), 1405-1407.
https://doi.org/10.1111/dme.14172, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53014
Marso, S., Bain, S., Baeres, F., Goldman, B., Husain, M., Nauck, M., Poulter, N., Pratley, R., Thomsen, A., & Buse, J. (2020). Effects of Liraglutide on Cardiovascular Outcomes in Patients With Diabetes With or Without Heart Failure. Journal of the American College of Cardiology, 75(10), 1128-1141.
https://doi.org/10.1016/j.jacc.2019.12.063, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53055
Husain, M., Bain, S., Jeppesen, O., Lingvay, I., Sørrig, R., Treppendahl, M., & Vilsbøll, T. (2020). Semaglutide (SUSTAIN and PIONEER) reduces cardiovascular events in type 2 diabetes across varying cardiovascular risk. Diabetes, Obesity and Metabolism, 22(3), 442-451.
https://doi.org/10.1111/dom.13955, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53094
Min, T. & Bain, S. (2020). Estimands in diabetes clinical trials. The Lancet Diabetes & Endocrinology, 8(3), 181-183.
https://doi.org/10.1016/s2213-8587(19)30407-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53432
Chudleigh, R., Platts, J., & Bain, S. (2020). Comparative Effectiveness of Long-Acting GLP-1 Receptor Agonists in Type 2 Diabetes: A Short Review on the Emerging Data. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 13, 433-438.
https://doi.org/10.2147/dmso.s193693, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53565
Kew, J. & Bain, S. (2020). An unusual skin rash in a person with type 1 diabetes. Diabetic Medicine, 37(9), 1607-1608.
https://doi.org/10.1111/dme.14263, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53667
Zayed, M. & Bain, S. (2020). A man with nodules on the backs of his hands. Diabetic Medicine, 37(10), 1766-1767.
https://doi.org/10.1111/dme.14269, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53692
Marso, S., Baeres, F., Bain, S., Goldman, B., Husain, M., Nauck, M., Poulter, N., Pratley, R., Thomsen, A., & Buse, J. (2020). Effects of Liraglutide on Cardiovascular Outcomes in Patients With Diabetes With or Without Heart Failure. Journal of the American College of Cardiology, 75(10), 1128-1141.
https://doi.org/10.1016/j.jacc.2019.12.063, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53812
Yin, W., Bain, S., & Min, T. (2020). The Effect of Glucagon-Like Peptide-1 Receptor Agonists on Renal Outcomes in Type 2 Diabetes. Diabetes Therapy, 11(4), 835-844.
https://doi.org/10.1007/s13300-020-00798-x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53944
Reed, J., Bain, S., & Kanamarlapudi, V. (2020). Recent advances in understanding the role of glucagon-like peptide 1. F1000Research, 9, 239
https://doi.org/10.12688/f1000research.20602.1, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54102
Vijayasingam, D. & Bain, S. (2020). A slightly itchy rash on the hand of a person with type 1 diabetes. Diabetic Medicine, 37(9), 1609-1610.
https://doi.org/10.1111/dme.14295, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54219
Buse, J., Bain, S., Mann, J., Nauck, M., Nissen, S., Pocock, S., Poulter, N., Pratley, R., Linder, M., Fries, T., Ørsted, D., Zinman, B., & Investigators), . (2020). Cardiovascular Risk Reduction With Liraglutide: An Exploratory Mediation Analysis of the LEADER Trial. Diabetes Care, dc192251
https://doi.org/10.2337/dc19-2251, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54312
Jódar, E., Michelsen, M., Polonsky, W., Réa, R., Sandberg, A., Vilsbøll, T., Warren, M., Harring, S., Ziegler, U., & Bain, S. (2020). Semaglutide improves health‐related quality of life versus placebo when added to standard of care in patients with type 2 diabetes at high cardiovascular risk (SUSTAIN 6). Diabetes, Obesity and Metabolism
https://doi.org/10.1111/dom.14039, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54313
Leiter, L., Bain, S., Bhatt, D., Buse, J., Mazer, C., Pratley, R., Rasmussen, S., Ripa, M., Vrazic, H., & Verma, S. (2020). The effect of glucagon‐like peptide‐1 receptor agonists liraglutide and semaglutide on cardiovascular and renal outcomes across baseline blood pressure categories: Analysis of the LEADER and SUSTAIN 6 trials. Diabetes, Obesity and Metabolism
https://doi.org/10.1111/dom.14079, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54314
Parsons, S., Luzio, S., Harvey, J., Bain, S., Cheung, I., Watkins, A., & Owens, D. (2019). Effect of structured self‐monitoring of blood glucose, with and without additional TeleCare support, on overall glycaemic control in non‐insulin treated Type 2 diabetes: the SMBG Study, a 12‐month randomized controlled trial. Diabetic Medicine, 36(5), 578-590.
https://doi.org/10.1111/dme.13899, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54346
Chudleigh, R. & Bain, S. (2020). Semaglutide injection for the treatment of adults with type 2 diabetes. Expert Review of Clinical Pharmacology, 13(7), 675-684.
https://doi.org/10.1080/17512433.2020.1776108, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54360
Verma, S., Bain, S., Honoré, J., Mann, J., Nauck, M., Pratley, R., Rasmussen, S., Ripa, M., Zinman, B., & Buse, J. (2020). Impact of microvascular disease on cardiovascular outcomes in type 2 diabetes: Results from the LEADER and SUSTAIN 6 clinical trials. Diabetes, Obesity and Metabolism, 22(11)
https://doi.org/10.1111/dom.14140, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54662
Mosenzon, O., Bain, S., Heerspink, H., Idorn, T., Mann, J., Persson, F., Pratley, R., Rasmussen, S., Rossing, P., Scholten, B., Raz, I., & Investigators), . (2020). Cardiovascular and renal outcomes by baseline albuminuria status and renal function: Results from the LEADER randomized trial. Diabetes, Obesity and Metabolism, 22(11), 2077-2088.
https://doi.org/10.1111/dom.14126, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54750
Turner, D., Luzio, S., Gray, B., Dunseath, G., Rees, E., Kilduff, L., Campbell, M., West, D., Bain, S., Bracken, R., Kilduff, L., Bracken, R., Bain, S., Dunseath, G., & Luzio, S. (2014). Impact of single and multiple sets of resistance exercise in type 1 diabetes. Scandinavian Journal of Medicine & Science in Sports, n/a-n/a.
https://doi.org/10.1111/sms.12202, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa18537
Turner, D., Luzio, S., Kilduff, L., Gray, B., Dunseath, G., Bain, S., Campbell, M., West, D., Bracken, R., Kilduff, L., Bracken, R., Bain, S., Dunseath, G., & Luzio, S. (2014). Reductions in resistance exercise-induced hyperglycaemic episodes are associated with circulating interleukin-6 in Type 1 diabetes. Diabetic Medicine, 31(8), 1009-1013.
https://doi.org/10.1111/dme.12462, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa18538
Campbell, M., West, D., Bain, S., Kingsley, M., Foley, P., Kilduff, L., Turner, D., Gray, B., Stephens, J., Bracken, R., Kilduff, L., Bracken, R., Stephens, J., & Bain, S. (2014). Simulated games activity vs continuous running exercise: A novel comparison of the glycemic and metabolic responses in T1DM patients. Scandinavian Journal of Medicine & Science in Sports, n/a-n/a.
https://doi.org/10.1111/sms.12192, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa19808
Heise, T., Bain, S., Bracken, R., Zijlstra, E., Nosek, L., Stender‐Petersen, K., Rabøl, R., Rowe, E., & Haahr, H. (2016). Similar risk of exercise‐related hypoglycaemia for insulin degludec to that for insulin glargine in patients with type 1 diabetes: a randomized cross‐over trial. Diabetes, Obesity and Metabolism, 18(2), 196-199.
https://doi.org/10.1111/dom.12588, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27008
http://dx.doi.org/10.1111/dom.12588
Parsons, S., Luzio, S., Bain, S., Harvey, J., McKenna, J., Khan, A., Rice, S., Watkins, A., Owens, D., & Bain, S. (2017). Self-monitoring of Blood Glucose in Non-Insulin Treated Type 2 Diabetes (The SMBG Study): study protocol for a randomised controlled trial. BMC Endocrine Disorders, 17(1)
https://doi.org/10.1186/s12902-017-0154-x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa32118
Moser, O., Eckstein, M., McCarthy, O., Deere, R., Bain, S., Haahr, H., Zijlstra, E., & Bracken, R. (2017). Poor glycaemic control is associated with reduced exercise performance and oxygen economy during cardio-pulmonary exercise testing in people with type 1 diabetes. Diabetology & Metabolic Syndrome, 9(1)
https://doi.org/10.1186/s13098-017-0294-1, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa37329
McCarthy, O., Moser, O., Eckstein, M., Bain, S., Pitt, J., & Bracken, R. (2019). Supplementary Nitric Oxide Donors and Exercise as Potential Means to Improve Vascular Health in People with Type 1 Diabetes: Yes to NO?. Nutrients, 11(7), 1571
https://doi.org/10.3390/nu11071571, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51072
Aroda, V., Capehorn, M., Chaykin, L., Frias, J., Lausvig, N., Macura, S., Lüdemann, J., Madsbad, S., Rosenstock, J., Tabak, O., Tadayon, S., & Bain, S. (2020). Impact of baseline characteristics and beta‐cell function on the efficacy and safety of subcutaneous once‐weekly semaglutide: A patient‐level, pooled analysis of the SUSTAIN 1‐5 trials. Diabetes, Obesity and Metabolism, 22(3), 303-314.
https://doi.org/10.1111/dom.13896, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52246
http://dx.doi.org/10.1111/dom.13896
Bain, S., Bakhai, A., Evans, M., Green, A., Menown, I., Strain, W., & Bain, S. (2019). Pharmacological treatment for Type 2 diabetes integrating findings from cardiovascular outcome trials: an expert consensus in the UK. Diabetic Medicine, 36(9), 1063-1071.
https://doi.org/10.1111/dme.14058, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51393
Ali, A., Bain, S., Hicks, D., Newland Jones, P., Patel, D., Evans, M., Fernando, K., James, J., Milne, N., Viljoen, A., & Wilding, J. (2019). SGLT2 Inhibitors: Cardiovascular Benefits Beyond HbA1c—Translating Evidence into Practice. Diabetes Therapy, 1-28.
https://doi.org/10.1007/s13300-019-0657-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51170
Bain, S., Bekker Hansen, B., Hunt, B., Chubb, B., Valentine, W., & Bain, S. (2019). Evaluating the burden of poor glycemic control associated with therapeutic inertia in patients with type 2 diabetes in the UK. Journal of Medical Economics, 1-8.
https://doi.org/10.1080/13696998.2019.1645018, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51093
Verma, S., Bain, S., Buse, J., Idorn, T., Rasmussen, S., Ørsted, D., & Nauck, M. (2019). Occurence of First and Recurrent Major Adverse Cardiovascular Events With Liraglutide Treatment Among Patients With Type 2 Diabetes and High Risk of Cardiovascular Events. JAMA Cardiology, 4(12), 1214
https://doi.org/10.1001/jamacardio.2019.3080, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51046
Tack, C., Jacob, S., Desouza, C., Bain, S., Buse, J., Nauck, M., Petrie, J., Poulter, N., Pratley, R., Stegmann, H., Bosch‐Traberg, H., Startseva, E., Zinman, B., & Bain, S. (2019). Long‐term efficacy and safety of combined insulin and GLP‐1 therapy: evidence from the LEADER trial. Diabetes, Obesity and Metabolism
https://doi.org/10.1111/dom.13826, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51012
Husain, M., Birkenfeld, A., Donsmark, M., Dungan, K., Eliaschewitz, F., Franco, D., Jeppesen, O., Lingvay, I., Mosenzon, O., Pedersen, S., Tack, C., Thomsen, M., Vilsbøll, T., Warren, M., & Bain, S. (2019). Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes. New England Journal of Medicine, 381(9), 841-851.
https://doi.org/10.1056/nejmoa1901118, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51010
O'Neil, L., Bain, S., & Bain, S. (2019). An unusual finding during retinal screening. Diabetic Medicine
https://doi.org/10.1111/dme.13971, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa50881
Verma, S., Bain, S., Monk Fries, T., Mazer, C., Nauck, M., Pratley, R., Rasmussen, S., Saevereid, H., Zinman, B., Buse, J., & Bain, S. (2019). Duration of diabetes and cardiorenal efficacy of liraglutide and semaglutide: A post hoc analysis of the LEADER and SUSTAIN 6 clinical trials. Diabetes, Obesity and Metabolism, 21(7), 1745-1751.
https://doi.org/10.1111/dom.13698, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa50827
Leiter, L., Bain, S., Hramiak, I., Jódar, E., Madsbad, S., Gondolf, T., Hansen, T., Holst, I., Lingvay, I., & Bain, S. (2019). Cardiovascular risk reduction with once-weekly semaglutide in subjects with type 2 diabetes: a post hoc analysis of gender, age, and baseline CV risk profile in the SUSTAIN 6 trial. Cardiovascular Diabetology, 18(1)
https://doi.org/10.1186/s12933-019-0871-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa50453
Taylor, K., Bain, S., & Bain, S. (2019). Foot deformity in a man with Type 2 diabetes. Diabetic Medicine
https://doi.org/10.1111/dme.13950, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa49901
Verma, S., Bain, S., Monk Fries, T., Mazer, C., Nauck, M., Pratley, R., Rasmussen, S., Saevereid, H., Zinman, B., Buse, J., & Bain, S. (2019). Duration of diabetes and cardiorenal efficacy of liraglutide and semaglutide: A post hoc analysis of the LEADER and SUSTAIN 6 clinical trials. Diabetes, Obesity and Metabolism
https://doi.org/10.1111/dom.13698, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa49876
Parsons, S., Luzio, S., Harvey, J., Bain, S., Cheung, W., Watkins, A., & Owens, D. (2019). Effect of structured self‐monitoring of blood glucose, with and without additional TeleCare support, on overall glycaemic control in non‐insulin treated Type 2 diabetes: the SMBG Study, a 12‐month randomized controlled trial. Diabetic Medicine, 36(5), 578-590.
https://doi.org/10.1111/dme.13899, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48683

All Research

Journal Articles

Bain, S. & Min, T. (2023). A new class of glucose-lowering therapy for type 2 diabetes: the latest development in the incretin arena. The Lancet, 402(10401)
https://doi.org/10.1016/s0140-6736(23)01182-0, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63790
http://dx.doi.org/10.1016/s0140-6736(23)01182-0
Moser, O., Rafferty, J., Eckstein, M., Aziz, F., Bain, S., Bergenstal, R., Sourij, H., Thomas, R., Rafferty, J., & Thomas, B. (2023). Impact of severe hypoglycaemia requiring hospitalization on mortality in people with type 1 diabetes: A national retrospective observational cohort study. Diabetes, Obesity and Metabolism, 25(8), 2243-2254.
https://doi.org/10.1111/dom.15102, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63220
http://dx.doi.org/10.1111/dom.15102
McCarthy, O., Christensen, M., Kristensen, K., Schmidt, S., Ranjan, A., Bain, S., Bracken, R., & Nørgaard, K. (2023). Automated Insulin Delivery Around Exercise in Adults with Type 1 Diabetes: A Pilot Randomized Controlled Study. Diabetes Technology & Therapeutics, 25(7), 476-484.
https://doi.org/10.1089/dia.2023.0009, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63844
http://dx.doi.org/10.1089/dia.2023.0009
Rosenstock, J., Bain, S., Gowda, A., Jódar, E., Liang, B., Lingvay, I., Nishida, T., Trevisan, R., & Mosenzon, O. (2023). Weekly Icodec versus Daily Glargine U100 in Type 2 Diabetes without Previous Insulin. New England Journal of Medicine, 389(4), 297-308.
https://doi.org/10.1056/nejmoa2303208, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63791
http://dx.doi.org/10.1056/nejmoa2303208
Hayes, J., Rafferty, J., Cheung, W., Akbari, A., Thomas, R., Bain, S., Topliss, C., & Stephens, J. (2023). Quantifying the incidence of lower limb amputation in people with and without diabetes in Wales between 2008–2018. Diabetes Epidemiology and Management, 11, 100144
https://doi.org/10.1016/j.deman.2023.100144, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63611
http://dx.doi.org/10.1016/j.deman.2023.100144
Bain, S., Carstensen, B., Hyveled, L., Seremetis, S., Kreiner, F., Amadid, H., & Clark, A. (2023). Glucagon-like peptide-1 receptor agonist use is associated with lower blood ferritin levels in people with type 2 diabetes and hemochromatosis: a nationwide register-based study. BMJ Open Diabetes Research & Care, 11(3), e003300
https://doi.org/10.1136/bmjdrc-2022-003300, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63949
http://dx.doi.org/10.1136/bmjdrc-2022-003300
Connolly, D., Zaman, A., Capps, N., Bain, S., & Fernando, K. (2023). Assessing opinion on lower LDL-cholesterol lowering, and the role of newer lipid-reducing treatment options. British Journal of Cardiology, 30
https://doi.org/10.5837/bjc.2023.014, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63663
Wijewickrama, P., Williams, J., Bain, S., Dasgupta, I., Chowdhury, T., Wahba, M., Frankel, A., Lambie, M., Karalliedde, J., Dasgupta, I., Chowdhury, T., Wahba, M., Frankel, A., & Karalliedde, J. (2023). Narrative Review of Glycemic Management in People With Diabetes on Peritoneal Dialysis. Kidney International Reports, 8(4), 700-714.
https://doi.org/10.1016/j.ekir.2023.01.040, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63333
http://dx.doi.org/10.1016/j.ekir.2023.01.040
Tuttle, K., Bosch-Traberg, H., Cherney, D., Hadjadj, S., Lawson, J., Mosenzon, O., Rasmussen, S., & Bain, S. (2023). Post hoc analysis of SUSTAIN 6 and PIONEER 6 trials suggests that people with type 2 diabetes at high cardiovascular risk treated with semaglutide experience more stable kidney function compared with placebo. Kidney International, 103(4), 772-781.
https://doi.org/10.1016/j.kint.2022.12.028, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63332
http://dx.doi.org/10.1016/j.kint.2022.12.028
Min, T. & Bain, S. (2023). Emerging drugs for the treatment of type 1 diabetes mellitus: a review of phase 2 clinical trials. Expert Opinion on Emerging Drugs, 28(1), 1-15.
https://doi.org/10.1080/14728214.2023.2188191, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62930
http://dx.doi.org/10.1080/14728214.2023.2188191
Evans, M., Berry, S., Nazeri, A., Malkin, S., Ashley, D., Hunt, B., & Bain, S. (2023). The challenges and pitfalls of incorporating evidence from cardiovascular outcomes trials in health economic modelling of type 2 diabetes. Diabetes, Obesity and Metabolism, 25(3), 639-648.
https://doi.org/10.1111/dom.14917, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62592
Viljoen, A. & Bain, S. (2023). Glucagon-Like Peptide 1 Therapy: From Discovery to Type 2 Diabetes and Beyond. Endocrinology and Metabolism, 38(1), 25-33.
https://doi.org/10.3803/enm.2022.1642, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62654
Williams, D., Crockett, E., Aye, S., Latheef, M., Chokor, M., Roberts, R., Bain, S., Stephens, J., & Min, T. (2023). Freestyle libre use in people with type 2 diabetes using basal-bolus insulin is associated with improved glycaemic control: A real-world analysis. Primary Care Diabetes, 17(2)
https://doi.org/10.1016/j.pcd.2023.01.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62662
McCarthy, O., Kristensen, K., Christensen, M., Schmidt, S., Ranjan, A., Nicholas, C., Bain, S., Nørgaard, K., & Bracken, R. (2023). Metabolic and physiological responses to graded exercise testing in individuals with type 1 diabetes using insulin pump therapy. Diabetes, Obesity and Metabolism, 25(3)
https://doi.org/10.1111/dom.14938, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62161
Bain, S. (2022). Fat – pharmacological therapies. British Journal of Diabetes, 22(Supplement 1), S59-S61.
https://doi.org/10.15277/bjd.2022.367, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62284
Bain, S. (2022). The place of Glucagon-like 1 peptide receptor agonists (GLP-1RAs) in the new NICE guidelines – what is going on?. British Journal of Diabetes, 22(2), 69-71.
https://doi.org/10.15277/bjd.2022.381, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62283
McCarthy, O., Schmidt, S., Christensen, M., Bain, S., Nørgaard, K., & Bracken, R. (2022). The endocrine pancreas during exercise in people with and without type 1 diabetes: Beyond the beta-cell. Frontiers in Endocrinology, 13
https://doi.org/10.3389/fendo.2022.981723, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa61554
Salem, A., Bain, S., & Obaid, D. (2022). Glucagon-like peptide-1 receptor agonists as anti-inflammatory agents: A potential mode of cardiovascular benefits. Atherosclerosis, 352, 83-84.
https://doi.org/10.1016/j.atherosclerosis.2022.05.010, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60290
Wylie, T., Morris, A., Robertson, E., Middleton, A., Newbert, C., Andersen, B., Maltese, G., Stocker, R., Weightman, A., Sinclair, A., & Bain, S. (2022). Ageing well with diabetes: A workshop to co‐design research recommendations for improving the diabetes care of older people. Diabetic Medicine, 39(7)
https://doi.org/10.1111/dme.14795, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59310
Evans, M., Morgan, A., Bain, S., Davies, S., Dashora, U., Sinha, S., Seidu, S., Patel, D., Beba, H., & Strain, W. (2022). Defining the Role of SGLT2 Inhibitors in Primary Care: Time to Think Differently. Diabetes Therapy, 13(5), 889-911.
https://doi.org/10.1007/s13300-022-01242-y, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59763
Wilding, J., Evans, M., Fernando, K., Gorriz, J., Cebrian, A., Diggle, J., Hicks, D., James, J., Newland-Jones, P., Ali, A., Bain, S., Porto, A., Patel, D., Viljoen, A., Wheeler, D., & Prato, S. (2022). The Place and Value of Sodium-Glucose Cotransporter 2 Inhibitors in the Evolving Treatment Paradigm for Type 2 Diabetes Mellitus: A Narrative Review. Diabetes Therapy, 13(5), 847-872.
https://doi.org/10.1007/s13300-022-01228-w, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59694
Husain, M., Consoli, A., Remigis, A., Meyer, A., Rasmussen, S., & Bain, S. (2022). Semaglutide reduces cardiovascular events regardless of metformin use: a post hoc subgroup analysis of SUSTAIN 6 and PIONEER 6. Cardiovascular Diabetology, 21(1)
https://doi.org/10.1186/s12933-022-01489-6, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59680
Karalliedde, J., Winocour, P., Chowdhury, T., De, P., Frankel, A., Montero, R., Pokrajac, A., Banerjee, D., Dasgupta, I., Fogarty, D., Sharif, A., Wahba, M., Mark, P., Zac‐Varghese, S., Patel, D., & Bain, S. (2022). Clinical practice guidelines for management of hyperglycaemia in adults with diabetic kidney disease. Diabetic Medicine, 39(4)
https://doi.org/10.1111/dme.14769, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59311
Banerjee, D., Winocour, P., Chowdhury, T., De, P., Wahba, M., Montero, R., Fogarty, D., Frankel, A., Goldet, G., Karalliedde, J., Mark, P., Patel, D., Pokrajac, A., Sharif, A., Zac-Varghese, S., Bain, S., & Dasgupta, I. (2022). Management of Hypertension in Patients With Diabetic Kidney Disease: Summary of the Joint Association of British Clinical Diabetologists and UK Kidney Association (ABCD-UKKA) Guideline 2021. Kidney International Reports, 7(4), 681-687.
https://doi.org/10.1016/j.ekir.2022.01.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59219
Williams, D., Staff, M., Bain, S., & Min, T. (2022). Glucagon-like Peptide-1 Receptor Analogues for the Treatment of Obesity. Endocrinology, 18(1), 43
https://doi.org/10.17925/ee.2022.18.1.43, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60990
Khunti, K., Hertz, C., Husemoen, L., Mocevic, E., Nordsborg, R., Piltoft, J., & Bain, S. (2022). Cardiovascular risk factors early in the course of treatment in people with type 2 diabetes without established cardiovascular disease: A population‐based observational retrospective cohort study. Diabetic Medicine, 39(3)
https://doi.org/10.1111/dme.14697, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57800
Shaman, A., Bain, S., Bakris, G., Buse, J., Idorn, T., Mahaffey, K., Mann, J., Nauck, M., Rasmussen, S., Rossing, P., Wolthers, B., Zinman, B., & Perkovic, V. (2022). Effect of the Glucagon-Like Peptide-1 Receptor Agonists Semaglutide and Liraglutide on Kidney Outcomes in Patients With Type 2 Diabetes: Pooled Analysis of SUSTAIN 6 and LEADER. Circulation, 145(8), 575-585.
https://doi.org/10.1161/circulationaha.121.055459, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59068
Evans, M., Morgan, A., Bain, S., Davies, S., Hicks, D., Brown, P., Yousef, Z., Dashora, U., Viljoen, A., Beba, H., & Strain, W. (2022). Meeting the Challenge of Virtual Diabetes Care: A Consensus Viewpoint on the Positioning and Value of Oral Semaglutide in Routine Clinical Practice. Diabetes Therapy, 13(2), 225-240.
https://doi.org/10.1007/s13300-021-01201-z, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59059
Evans, M., Morgan, A., Whyte, M., Hanif, W., Bain, S., Kalra, P., Davies, S., Dashora, U., Yousef, Z., Patel, D., & Strain, W. (2022). New Therapeutic Horizons in Chronic Kidney Disease: The Role of SGLT2 Inhibitors in Clinical Practice. Drugs, 82(2), 97-108.
https://doi.org/10.1007/s40265-021-01655-2, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa58766
Banerjee, D., Winocour, P., Chowdhury, T., De, P., Wahba, M., Montero, R., Fogarty, D., Frankel, A., Karalliedde, J., Mark, P., Patel, D., Pokrajac, A., Sharif, A., Zac-Varghese, S., Bain, S., Dasgupta, I., & Association), . (2022). Management of hypertension and renin-angiotensin-aldosterone system blockade in adults with diabetic kidney disease: Association of British Clinical Diabetologists and the Renal Association UK guideline update 2021. BMC Nephrology, 23(1)
https://doi.org/10.1186/s12882-021-02587-5, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59060
Evans, M., Lewis, R., Morgan, A., Whyte, M., Hanif, W., Bain, S., Davies, S., Dashora, U., Yousef, Z., Patel, D., & Strain, W. (2022). A Narrative Review of Chronic Kidney Disease in Clinical Practice: Current Challenges and Future Perspectives. Advances in Therapy, 39(1), 33-43.
https://doi.org/10.1007/s12325-021-01927-z, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa58735
Bain, E. & Bain, S. (2021). Recent developments in GLP‐1RA therapy: A review of the latest evidence of efficacy and safety and differences within the class. Diabetes, Obesity and Metabolism, 23(S3), 30-39.
https://doi.org/10.1111/dom.14487, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa58129
Fernando, K., Bain, S., Holmes, P., Jones, P., & Patel, D. (2021). Glucagon-Like Peptide 1 Receptor Agonist Usage in Type 2 Diabetes in Primary Care for the UK and Beyond: A Narrative Review. Diabetes Therapy, 12(9), 2267-2288.
https://doi.org/10.1007/s13300-021-01116-9, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa58128
Reed, J., Bain, S., & Kanamarlapudi, V. (2021). A Review of Current Trends with Type 2 Diabetes Epidemiology, Aetiology, Pathogenesis, Treatments and Future Perspectives. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 14, 3567-3602.
https://doi.org/10.2147/dmso.s319895, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57318
Saunders, I. & Bain, S. (2021). A woman with poorly controlled type 1 diabetes and pruritic papules on her buttocks. Diabetic Medicine, 38(8)
https://doi.org/10.1111/dme.14539, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56314
McCarthy, O., Pitt, J., ECKSTEIN, M., MOSER, O., Bain, S., & Bracken, R. (2021). Pancreatic β-Cell Function Is Associated with Augmented Counterregulation to In-Exercise Hypoglycemia in Type 1 Diabetes. Medicine & Science in Sports & Exercise, 53(7), 1326-1333.
https://doi.org/10.1249/mss.0000000000002613, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57228
Evans, M., Morgan, A., Yousef, Z., Ellis, G., Dashora, U., Patel, D., Brown, P., Hanif, W., Townend, J., Kanumilli, N., Moore, J., Wilding, J., & Bain, S. (2021). Optimising the Heart Failure Treatment Pathway: The Role of SGLT2 Inhibitors. Drugs, 81(11), 1243-1255.
https://doi.org/10.1007/s40265-021-01538-6, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56924
Chowdhury, T., Wahba, M., Mallik, R., Peracha, J., Patel, D., De, P., Fogarty, D., Frankel, A., Karalliedde, J., Mark, P., Montero, R., Pokrajac, A., Zac‐Varghese, S., Bain, S., Dasgupta, I., Banerjee, D., Winocour, P., & Sharif, A. (2021). Association of British Clinical Diabetologists and Renal Association guidelines on the detection and management of diabetes post solid organ transplantation. Diabetic Medicine, 38(6)
https://doi.org/10.1111/dme.14523, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55995
Bain, S., Rickford, A., Black, N., Hamilton, L., Camfield, E., Chamley, M., Hodgkinson, A., & Karalliedde, J. (2021). Delivering joined-up care for people with type 2 diabetes: rationale, challenges and examples. British Journal of Diabetes, 21(1), 89-95.
https://doi.org/10.15277/bjd.2021.294, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56389
Rafferty, J., Stephens, J., Atkinson, M., Luzio, S., Akbari, A., Gregory, J., Bain, S., Owens, D., & Thomas, B. (2021). A retrospective epidemiological study of Type 1 Diabetes Mellitus in Wales, UK between 2008 and 2018. International Journal of Population Data Science, 6(1)
https://doi.org/10.23889/ijpds.v6i1.1387, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56716
Herrath, M., Bain, S., Bode, B., Clausen, J., Coppieters, K., Gaysina, L., Gumprecht, J., Hansen, T., Mathieu, C., Morales, C., Mosenzon, O., Segel, S., Tsoukas, G., Pieber, T., Ludvik, B., Prager, R., Paulweber, B., Ebenbichler, C., Keymeulen, B...., & Kreiner, F. (2021). Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial. The Lancet Diabetes & Endocrinology, 9(4), 212-224.
https://doi.org/10.1016/s2213-8587(21)00019-x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56262
http://dx.doi.org/10.1016/s2213-8587(21)00019-x
Persson, F., Bain, S., Mosenzon, O., Heerspink, H., Mann, J., Pratley, R., Raz, I., Idorn, T., Rasmussen, S., Scholten, B., & Rossing, P. (2021). Changes in Albuminuria Predict Cardiovascular and Renal Outcomes in Type 2 Diabetes: A Post Hoc Analysis of the LEADER Trial. Diabetes Care, 44(4), 1020-1026.
https://doi.org/10.2337/dc20-1622, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55970
Williams, D., Ruslan, A., Khan, R., Vijayasingam, D., Iqbal, F., Shaikh, A., Lim, J., Chudleigh, R., Peter, R., Udiawar, M., Bain, S., Stephens, J., & Min, T. (2021). Real-World Clinical Experience of Semaglutide in Secondary Care Diabetes: A Retrospective Observational Study. Diabetes Therapy, 12(3), 801-811.
https://doi.org/10.1007/s13300-021-01015-z, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56157
McCarthy, O., Deere, R., Eckstein, M., Pitt, J., Wellman, B., Bain, S., Moser, O., & Bracken, R. (2021). Improved Nocturnal Glycaemia and Reduced Insulin Use Following Clinical Exercise Trial Participation in Individuals With Type 1 Diabetes. Frontiers in Public Health, 8
https://doi.org/10.3389/fpubh.2020.568832, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55783
McCarthy, O., Deere, R., Churm, R., Dunseath, G., Jones, C., Eckstein, M., Williams, D., Hayes, J., Pitt, J., Bain, S., Moser, O., & Bracken, R. (2021). Extent and prevalence of post-exercise and nocturnal hypoglycemia following peri-exercise bolus insulin adjustments in individuals with type 1 diabetes. Nutrition, Metabolism and Cardiovascular Diseases, 31(1), 227-236.
https://doi.org/10.1016/j.numecd.2020.07.043, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55261
Bain, S., Czernichow, S., Bøgelund, M., Madsen, M., Yssing, C., McMillan, A., Hvid, C., Hettiarachchige, N., & Panton, U. (2021). Costs of COVID-19 pandemic associated with diabetes in Europe: a health care cost model. Current Medical Research and Opinion, 37(1), 27-36.
https://doi.org/10.1080/03007995.2020.1862775, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55911
Min, T. & Bain, S. (2021). The Role of Tirzepatide, Dual GIP and GLP-1 Receptor Agonist, in the Management of Type 2 Diabetes: The SURPASS Clinical Trials. Diabetes Therapy, 12(1), 143-157.
https://doi.org/10.1007/s13300-020-00981-0, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55784
Verma, S., McGuire, D., Bain, S., Bhatt, D., Leiter, L., Mazer, C., Fries, T., Pratley, R., Rasmussen, S., Vrazic, H., Zinman, B., & Buse, J. (2020). Effects of glucagon-like peptide-1 receptor agonists liraglutide and semaglutide on cardiovascular and renal outcomes across body mass index categories in type 2 diabetes: Results of the LEADER and SUSTAIN 6 trials. Diabetes, Obesity and Metabolism, 22(12), 2487-2492.
https://doi.org/10.1111/dom.14160, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54840
Husain, M., Bain, S., Holst, A., Mark, T., Rasmussen, S., & Lingvay, I. (2020). Effects of semaglutide on risk of cardiovascular events across a continuum of cardiovascular risk: combined post hoc analysis of the SUSTAIN and PIONEER trials. Cardiovascular Diabetology, 19(1)
https://doi.org/10.1186/s12933-020-01106-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54830
Mosenzon, O., Bain, S., Heerspink, H., Idorn, T., Mann, J., Persson, F., Pratley, R., Rasmussen, S., Rossing, P., Scholten, B., Raz, I., & Investigators), . (2020). Cardiovascular and renal outcomes by baseline albuminuria status and renal function: Results from the LEADER randomized trial. Diabetes, Obesity and Metabolism, 22(11), 2077-2088.
https://doi.org/10.1111/dom.14126, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54750
McCarthy, O., Pitt, J., Churm, R., Dunseath, G., Jones, C., Bally, L., Nakas, C., Deere, R., Eckstein, M., Bain, S., Moser, O., & Bracken, R. (2020). Metabolomic, hormonal and physiological responses to hypoglycemia versus euglycemia during exercise in adults with type 1 diabetes. BMJ Open Diabetes Research & Care, 8(1)
https://doi.org/10.1136/bmjdrc-2020-001577, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55338
Zayed, M. & Bain, S. (2020). A man with nodules on the backs of his hands. Diabetic Medicine, 37(10), 1766-1767.
https://doi.org/10.1111/dme.14269, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53692
Kew, J. & Bain, S. (2020). An unusual skin rash in a person with type 1 diabetes. Diabetic Medicine, 37(9), 1607-1608.
https://doi.org/10.1111/dme.14263, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53667
Vijayasingam, D. & Bain, S. (2020). A slightly itchy rash on the hand of a person with type 1 diabetes. Diabetic Medicine, 37(9), 1609-1610.
https://doi.org/10.1111/dme.14295, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54219
Verma, S., Bain, S., Honoré, J., Mann, J., Nauck, M., Pratley, R., Rasmussen, S., Ripa, M., Zinman, B., & Buse, J. (2020). Impact of microvascular disease on cardiovascular outcomes in type 2 diabetes: Results from the LEADER and SUSTAIN 6 clinical trials. Diabetes, Obesity and Metabolism, 22(11)
https://doi.org/10.1111/dom.14140, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54662
Bain, S., Bakhai, A., Evans, M., Green, A., Menown, I., & Strain, W. (2020). An update to: Pharmacological treatment for type 2 diabetes integrating findings from cardiovascular outcome trials: an expert consensus in the UK. Diabet Med 2019; 36: 1063–1071. Diabetic Medicine, 37(8), 1405-1407.
https://doi.org/10.1111/dme.14172, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53014
Chudleigh, R. & Bain, S. (2020). Semaglutide injection for the treatment of adults with type 2 diabetes. Expert Review of Clinical Pharmacology, 13(7), 675-684.
https://doi.org/10.1080/17512433.2020.1776108, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54360
Leiter, L., Bain, S., Bhatt, D., Buse, J., Mazer, C., Pratley, R., Rasmussen, S., Ripa, M., Vrazic, H., & Verma, S. (2020). The effect of glucagon‐like peptide‐1 receptor agonists liraglutide and semaglutide on cardiovascular and renal outcomes across baseline blood pressure categories: Analysis of the LEADER and SUSTAIN 6 trials. Diabetes, Obesity and Metabolism
https://doi.org/10.1111/dom.14079, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54314
Buse, J., Bain, S., Mann, J., Nauck, M., Nissen, S., Pocock, S., Poulter, N., Pratley, R., Linder, M., Fries, T., Ørsted, D., Zinman, B., & Investigators), . (2020). Cardiovascular Risk Reduction With Liraglutide: An Exploratory Mediation Analysis of the LEADER Trial. Diabetes Care, dc192251
https://doi.org/10.2337/dc19-2251, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54312
Jódar, E., Michelsen, M., Polonsky, W., Réa, R., Sandberg, A., Vilsbøll, T., Warren, M., Harring, S., Ziegler, U., & Bain, S. (2020). Semaglutide improves health‐related quality of life versus placebo when added to standard of care in patients with type 2 diabetes at high cardiovascular risk (SUSTAIN 6). Diabetes, Obesity and Metabolism
https://doi.org/10.1111/dom.14039, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54313
Reed, J., Bain, S., & Kanamarlapudi, V. (2020). Recent advances in understanding the role of glucagon-like peptide 1. F1000Research, 9, 239
https://doi.org/10.12688/f1000research.20602.1, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54102
Yin, W., Bain, S., & Min, T. (2020). The Effect of Glucagon-Like Peptide-1 Receptor Agonists on Renal Outcomes in Type 2 Diabetes. Diabetes Therapy, 11(4), 835-844.
https://doi.org/10.1007/s13300-020-00798-x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53944
Marso, S., Bain, S., Baeres, F., Goldman, B., Husain, M., Nauck, M., Poulter, N., Pratley, R., Thomsen, A., & Buse, J. (2020). Effects of Liraglutide on Cardiovascular Outcomes in Patients With Diabetes With or Without Heart Failure. Journal of the American College of Cardiology, 75(10), 1128-1141.
https://doi.org/10.1016/j.jacc.2019.12.063, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53055
Marso, S., Baeres, F., Bain, S., Goldman, B., Husain, M., Nauck, M., Poulter, N., Pratley, R., Thomsen, A., & Buse, J. (2020). Effects of Liraglutide on Cardiovascular Outcomes in Patients With Diabetes With or Without Heart Failure. Journal of the American College of Cardiology, 75(10), 1128-1141.
https://doi.org/10.1016/j.jacc.2019.12.063, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53812
Husain, M., Bain, S., Jeppesen, O., Lingvay, I., Sørrig, R., Treppendahl, M., & Vilsbøll, T. (2020). Semaglutide (SUSTAIN and PIONEER) reduces cardiovascular events in type 2 diabetes across varying cardiovascular risk. Diabetes, Obesity and Metabolism, 22(3), 442-451.
https://doi.org/10.1111/dom.13955, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53094
Min, T. & Bain, S. (2020). Estimands in diabetes clinical trials. The Lancet Diabetes & Endocrinology, 8(3), 181-183.
https://doi.org/10.1016/s2213-8587(19)30407-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53432
Aroda, V., Capehorn, M., Chaykin, L., Frias, J., Lausvig, N., Macura, S., Lüdemann, J., Madsbad, S., Rosenstock, J., Tabak, O., Tadayon, S., & Bain, S. (2020). Impact of baseline characteristics and beta‐cell function on the efficacy and safety of subcutaneous once‐weekly semaglutide: A patient‐level, pooled analysis of the SUSTAIN 1‐5 trials. Diabetes, Obesity and Metabolism, 22(3), 303-314.
https://doi.org/10.1111/dom.13896, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52246
http://dx.doi.org/10.1111/dom.13896
Chudleigh, R., Platts, J., & Bain, S. (2020). Comparative Effectiveness of Long-Acting GLP-1 Receptor Agonists in Type 2 Diabetes: A Short Review on the Emerging Data. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 13, 433-438.
https://doi.org/10.2147/dmso.s193693, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53565
Chudleigh, R. & Bain, S. (2020). Efficacy of newer agents in the glycaemic management of patients with type 2 diabetes. Current Medical Research and Opinion, 36(2), 209-211.
https://doi.org/10.1080/03007995.2019.1678344, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52648
Bain, S., Feher, M., Fisher, M., Hex, N., Lee, K., Mahon, J., Russell‐Jones, D., Schou, H., Wilmot, E., & Baxter, M. (2020). A review of the NG17 recommendations for the use of basal insulin in type 1 diabetes. Diabetic Medicine, 37(2), 219-228.
https://doi.org/10.1111/dme.14180, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52764
Bain, S., Hansen, B., Malkin, S., Nuhoho, S., Valentine, W., Chubb, B., Hunt, B., & Capehorn, M. (2020). Oral Semaglutide Versus Empagliflozin, Sitagliptin and Liraglutide in the UK: Long-Term Cost-Effectiveness Analyses Based on the PIONEER Clinical Trial Programme. Diabetes Therapy, 11(1), 259-277.
https://doi.org/10.1007/s13300-019-00736-6, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52765
Ali, A., Bain, S., Hicks, D., Newland Jones, P., Patel, D., Evans, M., Fernando, K., James, J., Milne, N., Viljoen, A., & Wilding, J. (2019). SGLT2 Inhibitors: Cardiovascular Benefits Beyond HbA1c—Translating Evidence into Practice. Diabetes Therapy, 1-28.
https://doi.org/10.1007/s13300-019-0657-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51170
Verma, S., Bain, S., Buse, J., Idorn, T., Rasmussen, S., Ørsted, D., & Nauck, M. (2019). Occurence of First and Recurrent Major Adverse Cardiovascular Events With Liraglutide Treatment Among Patients With Type 2 Diabetes and High Risk of Cardiovascular Events. JAMA Cardiology, 4(12), 1214
https://doi.org/10.1001/jamacardio.2019.3080, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51046
Tack, C., Jacob, S., Desouza, C., Bain, S., Buse, J., Nauck, M., Petrie, J., Poulter, N., Pratley, R., Stegmann, H., Bosch‐Traberg, H., Startseva, E., Zinman, B., & Bain, S. (2019). Long‐term efficacy and safety of combined insulin and GLP‐1 therapy: evidence from the LEADER trial. Diabetes, Obesity and Metabolism
https://doi.org/10.1111/dom.13826, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51012
O'Neil, L., Bain, S., & Bain, S. (2019). An unusual finding during retinal screening. Diabetic Medicine
https://doi.org/10.1111/dme.13971, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa50881
Leiter, L., Bain, S., Hramiak, I., Jódar, E., Madsbad, S., Gondolf, T., Hansen, T., Holst, I., Lingvay, I., & Bain, S. (2019). Cardiovascular risk reduction with once-weekly semaglutide in subjects with type 2 diabetes: a post hoc analysis of gender, age, and baseline CV risk profile in the SUSTAIN 6 trial. Cardiovascular Diabetology, 18(1)
https://doi.org/10.1186/s12933-019-0871-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa50453
Taylor, K., Bain, S., & Bain, S. (2019). Foot deformity in a man with Type 2 diabetes. Diabetic Medicine
https://doi.org/10.1111/dme.13950, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa49901
Davies, M., Bain, S., Charpentier, G., Flacke, F., Goyeau, H., Woloschak, M., Hasslacher, C., Vespasiani, G., & Edelman, S. (2019). A Randomized Controlled, Treat-to-Target Study Evaluating the Efficacy and Safety of Insulin Glargine 300 U/mL (Gla-300) Administered Using Either Device-Supported or Routine Titration in People With Type 2 Diabetes. Journal of Diabetes Science and Technology, 193229681882170
https://doi.org/10.1177/1932296818821706, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46119
Verma, S., Bain, S., Buse, J., Idorn, T., Rasmussen, S., Ørsted, D., & Nauck, M. (2019). Occurence of First and Recurrent Major Adverse Cardiovascular Events With Liraglutide Treatment Among Patients With Type 2 Diabetes and High Risk of Cardiovascular Events. JAMA Cardiology, 4(12), 1214
https://doi.org/10.1001/jamacardio.2019.3080, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52744
Fulcher, G., Mehta, R., Fita, E., Ekelund, M., Bain, S., & Bain, S. (2019). Efficacy and Safety of IDegAsp Versus BIAsp 30, Both Twice Daily, in Elderly Patients with Type 2 Diabetes: Post Hoc Analysis of Two Phase 3 Randomized Controlled BOOST Trials. Diabetes Therapy, 10(1), 107-118.
https://doi.org/10.1007/s13300-018-0531-0, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45467
Bain, S. (2019). Oral Semaglutide and Cardiovascular Outcomes in Type 2 Diabetes. New England Journal of Medicine, 381(21), 2075-2077.
https://doi.org/10.1056/nejmc1913157, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52897
Moser, O., Eckstein, M., McCarthy, O., Deere, R., Pitt, J., Williams, D., Hayes, J., Sourij, H., Bain, S., & Bracken, R. (2019). Performance of the Freestyle Libre flash glucose monitoring (flash GM) system in individuals with type 1 diabetes: A secondary outcome analysis of a randomized crossover trial. Diabetes, Obesity and Metabolism, 21(11), 2505-2512.
https://doi.org/10.1111/dom.13835, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51468
Bain, S., Bakhai, A., Evans, M., Green, A., Menown, I., Strain, W., & Bain, S. (2019). Pharmacological treatment for Type 2 diabetes integrating findings from cardiovascular outcome trials: an expert consensus in the UK. Diabetic Medicine, 36(9), 1063-1071.
https://doi.org/10.1111/dme.14058, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51393
Husain, M., Birkenfeld, A., Donsmark, M., Dungan, K., Eliaschewitz, F., Franco, D., Jeppesen, O., Lingvay, I., Mosenzon, O., Pedersen, S., Tack, C., Thomsen, M., Vilsbøll, T., Warren, M., & Bain, S. (2019). Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes. New England Journal of Medicine, 381(9), 841-851.
https://doi.org/10.1056/nejmoa1901118, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51010
Bain, S., Bekker Hansen, B., Hunt, B., Chubb, B., Valentine, W., & Bain, S. (2019). Evaluating the burden of poor glycemic control associated with therapeutic inertia in patients with type 2 diabetes in the UK. Journal of Medical Economics, 1-8.
https://doi.org/10.1080/13696998.2019.1645018, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51093
Verma, S., Bain, S., Monk Fries, T., Mazer, C., Nauck, M., Pratley, R., Rasmussen, S., Saevereid, H., Zinman, B., Buse, J., & Bain, S. (2019). Duration of diabetes and cardiorenal efficacy of liraglutide and semaglutide: A post hoc analysis of the LEADER and SUSTAIN 6 clinical trials. Diabetes, Obesity and Metabolism, 21(7), 1745-1751.
https://doi.org/10.1111/dom.13698, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa50827
McCarthy, O., Moser, O., Eckstein, M., Bain, S., Pitt, J., & Bracken, R. (2019). Supplementary Nitric Oxide Donors and Exercise as Potential Means to Improve Vascular Health in People with Type 1 Diabetes: Yes to NO?. Nutrients, 11(7), 1571
https://doi.org/10.3390/nu11071571, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51072
Parsons, S., Luzio, S., Harvey, J., Bain, S., Cheung, I., Watkins, A., & Owens, D. (2019). Effect of structured self‐monitoring of blood glucose, with and without additional TeleCare support, on overall glycaemic control in non‐insulin treated Type 2 diabetes: the SMBG Study, a 12‐month randomized controlled trial. Diabetic Medicine, 36(5), 578-590.
https://doi.org/10.1111/dme.13899, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54346
Parsons, S., Luzio, S., Harvey, J., Bain, S., Cheung, W., Watkins, A., & Owens, D. (2019). Effect of structured self‐monitoring of blood glucose, with and without additional TeleCare support, on overall glycaemic control in non‐insulin treated Type 2 diabetes: the SMBG Study, a 12‐month randomized controlled trial. Diabetic Medicine, 36(5), 578-590.
https://doi.org/10.1111/dme.13899, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48683
Verma, S., Bain, S., Monk Fries, T., Mazer, C., Nauck, M., Pratley, R., Rasmussen, S., Saevereid, H., Zinman, B., Buse, J., & Bain, S. (2019). Duration of diabetes and cardiorenal efficacy of liraglutide and semaglutide: A post hoc analysis of the LEADER and SUSTAIN 6 clinical trials. Diabetes, Obesity and Metabolism
https://doi.org/10.1111/dom.13698, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa49876
Viljoen, A., Hoxer, C., Johansen, P., Malkin, S., Hunt, B., Bain, S., & Bain, S. (2018). Evaluation of the long-term cost-effectiveness of once-weekly semaglutide versus dulaglutide for treatment of type 2 diabetes mellitus in the UK. Diabetes, Obesity and Metabolism
https://doi.org/10.1111/dom.13564, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48008
McCarthy, O., Bain, S., & Deere, R. (2018). Basal insulin reductions in anticipation of multiple exercise sessions in people with type 1 diabetes—a clinical perspective. Annals of Translational Medicine, 6(S2), S111-S111.
https://doi.org/10.21037/atm.2018.11.63, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46118
Bain, S., Mosenzon, O., Arechavaleta, R., Bogdański, P., Comlekci, A., Consoli, A., Deerochanawong, C., Dungan, K., Faingold, M., Farkouh, M., Franco, D., Gram, J., Guja, C., Joshi, P., Malek, R., Merino-Torres, J., Nauck, M., Pedersen, S., Sheu, W...., & Bain, S. (2018). Cardiovascular safety of oral semaglutide in patients with type 2 diabetes: Rationale, design and patient baseline characteristics for the PIONEER 6 trial. Diabetes, Obesity and Metabolism
https://doi.org/10.1111/dom.13553, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa44806
Bain, S., Klufas, M., Ho, A., Matthews, D., & Bain, S. (2018). Worsening of diabetic retinopathy with rapid improvement in systemic glucose control: A review. Diabetes, Obesity and Metabolism
https://doi.org/10.1111/dom.13538, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa43853
Wilding, J., Fernando, K., Milne, N., Evans, M., Ali, A., Bain, S., Hicks, D., James, J., Newland-Jones, P., Patel, D., & Viljoen, A. (2018). SGLT2 Inhibitors in Type 2 Diabetes Management: Key Evidence and Implications for Clinical Practice. Diabetes Therapy
https://doi.org/10.1007/s13300-018-0471-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa41117
Vilsbøll, T., Bain, S., Leiter, L., Lingvay, I., Matthews, D., Simó, R., Helmark, I., Wijayasinghe, N., Larsen, M., & Bain, S. (2018). Semaglutide, reduction in glycated haemoglobin and the risk of diabetic retinopathy. Diabetes, Obesity and Metabolism, 20(4), 889-897.
https://doi.org/10.1111/dom.13172, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa37104
Verma, S., Poulter, N., Bhatt, D., Bain, S., Buse, J., Leiter, L., Nauck, M., Pratley, R., Zinman, B., Ørsted, D., Fries, T., Rasmussen, S., Marso, S., & Investigators), . (2018). Effects of Liraglutide on Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus With or Without History of Myocardial Infarction or Stroke. Circulation, 138(25), 2884-2894.
https://doi.org/10.1161/circulationaha.118.034516, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48035
Gilbert, M., Bain, S., Franek, E., Jodar-Gimeno, E., Nauck, M., Pratley, R., Réa, R., Saraiva, J., Rasmussen, S., Tornøe, K., Scholten, B., Buse, J., & Bain, S. (2018). Effect of Liraglutide on Cardiovascular Outcomes in Elderly Patients: A Post Hoc Analysis of a Randomized Controlled Trial. Annals of Internal Medicine
https://doi.org/10.7326/M18-1569, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa44926
Williams, D., Shrikrishnapalasuriyar, N., Syed, W., Yin, W., Chudleigh, R., Bain, S., Price, D., Stephens, J., & Bain, S. (2018). Real-world clinical experience of Xultophy in the management of patients with type 2 diabetes in a secondary care clinic. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 12(6), 1079-1082.
https://doi.org/10.1016/j.dsx.2018.06.029, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa40924
Dhatariya, K., Bain, S., Buse, J., Simpson, R., Tarnow, L., Kaltoft, M., Stellfeld, M., Tornøe, K., Pratley, R., & Bain, S. (2018). The Impact of Liraglutide on Diabetes-Related Foot Ulceration and Associated Complications in Patients With Type 2 Diabetes at High Risk for Cardiovascular Events: Results From the LEADER Trial. Diabetes Care, 41(10), 2229-2235.
https://doi.org/10.2337/dc18-1094, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa40954
Pang, T., Bain, S., Black, R., Boyle, J., Elliott, J., Holcombe, A., Lee, K., Mulligan, C., Saunders, L., Yousseif, A., Baxter, M., & Bain, S. (2018). A multicentre, UK, retrospective, observational study to assess the effectiveness of insulin glargine 300 units/ml in treating people with Type 1 diabetes mellitus in routine clinical practice (SPARTA). Diabetic Medicine
https://doi.org/10.1111/dme.13847, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa44625
Mathieu, C., Dandona, P., Gillard, P., Senior, P., Hasslacher, C., Araki, E., Lind, M., Bain, S., Jabbour, S., Arya, N., Hansen, L., Thorén, F., Langkilde, A., & Bain, S. (2018). Efficacy and Safety of Dapagliflozin in Patients With Inadequately Controlled Type 1 Diabetes (the DEPICT-2 Study): 24-Week Results From a Randomized Controlled Trial. Diabetes Care, 41(9), 1938-1946.
https://doi.org/10.2337/dc18-0623, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa43485
Bashir, J., Nalla, P., Peter, R., Bain, S., Chudleigh, R., & Bain, S. (2018). A case series of DKA occurring in patients receiving treatment with SGLT-2 inhibitors. Diabetes, Obesity and Metabolism, 20(7), 1800-1801.
https://doi.org/10.1111/dom.13271, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38873
Winocour, P., Bain, S., Chowdhury, T., De, P., Pokrajac, A., Fogarty, D., Frankel, A., Banerjee, D., Wahba, M., Dasgupta, I., & Bain, S. (2018). Managing hyperglycaemia in patients with diabetes and diabetic nephropathy–chronic kidney disease Summary of recommendations 2018. British Journal of Diabetes, 18(2), 78-89.
https://doi.org/10.15277/bjd.2018.172, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa40521
Field, B., Nayar, R., Kilvert, A., Baxter, M., Hickey, J., Cummings, M., Bain, S., & Bain, S. (2018). A retrospective observational study of people with Type 1 diabetes with self-reported severe hypoglycaemia reveals high level of ambulance attendance but low levels of therapy change and specialist intervention. Diabetic Medicine, 35(9), 1223-1231.
https://doi.org/10.1111/dme.13670, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa39203
Verma, S., Bhatt, D., Bain, S., Buse, J., Mann, J., Marso, S., Nauck, M., Poulter, N., Pratley, R., Zinman, B., Michelsen, M., Fries, T., Rasmussen, S., Leiter, L., & Bain, S. (2018). Effect of Liraglutide on Cardiovascular Events in Patients With Type 2 Diabetes Mellitus and Polyvascular Disease. Circulation, 137(20), 2179-2183.
https://doi.org/10.1161/CIRCULATIONAHA.118.033898, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38874
Thong, K., Yadagiri, M., Barnes, D., Morris, D., Chowdhury, T., Chuah, L., Robinson, A., Bain, S., Adamson, K., Ryder, R., & Bain, S. (2018). Clinical risk factors predicting genital fungal infections with sodium–glucose cotransporter 2 inhibitor treatment: The ABCD nationwide dapagliflozin audit. Primary Care Diabetes
https://doi.org/10.1016/j.pcd.2017.06.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa34717
Dasgupta, I., Banerjee, D., Chowdhury, T., De, P., Wahba, M., Bain, S., Frankel, A., Fogarty, D., Pokrajac, A., Winocour, P., & Bain, S. (2017). Association of British Clinical Diabetologists (ABCD) and Renal Association clinical guidelines: Hypertension management and renin-angiotensin-aldosterone system blockade in patients with diabetes, nephropathy and/or chronic kidney disease. British Journal of Diabetes, 17(4), 160-164.
https://doi.org/10.15277/bjd.2017.152, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa37652
Reed, J., Kanamarlapudi, V., Bain, S., & Bain, S. (2017). Mechanism of cardiovascular disease benefit of glucagon-like peptide 1 agonists. Cardiovascular Endocrinology, 7(1), 18-23.
https://doi.org/10.1097/XCE.0000000000000147, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa37335
Barnard, K., Kropff, J., Choudhary, P., Neupane, S., Bain, S., Kapitza, C., Forst, T., Link, M., Mdingi, C., DeVries, J., & Bain, S. (2017). Acceptability of Implantable Continuous Glucose Monitoring Sensor. Journal of Diabetes Science and Technology, 193229681773512
https://doi.org/10.1177/1932296817735123, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa35082
Chudleigh, R. & Bain, S. (2017). Cardiovascular safety of liraglutide for the treatment of Type 2 diabetes. Expert Opinion on Drug Safety
https://doi.org/10.1080/14740338.2017.1313225, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa32907
Moser, O., Eckstein, M., McCarthy, O., Deere, R., Bain, S., Haahr, H., Zijlstra, E., & Bracken, R. (2017). Poor glycaemic control is associated with reduced exercise performance and oxygen economy during cardio-pulmonary exercise testing in people with type 1 diabetes. Diabetology & Metabolic Syndrome, 9(1)
https://doi.org/10.1186/s13098-017-0294-1, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa37329
Chudleigh, R., Bain, S., & Bain, S. (2017). Semaglutide. GLP-1 receptor agonist, Treatment of type 2 diabetes. Drugs of the Future, 42(8), 479
https://doi.org/10.1358/dof.2017.042.08.2653526, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa35930
Aroda, V., Bain, S., Cariou, B., Piletič, M., Rose, L., Axelsen, M., Rowe, E., & DeVries, J. (2017). Efficacy and safety of once-weekly semaglutide versus once-daily insulin glargine as add-on to metformin (with or without sulfonylureas) in insulin-naive patients with type 2 diabetes (SUSTAIN 4): a randomised, open-label, parallel-group, multicentre, multinational, phase 3a trial. The Lancet Diabetes and Endocrinology, 5(5), 355-366.
https://doi.org/10.1016/S2213-8587(17)30085-2, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa31639
Sorli, C., Harashima, S., Tsoukas, G., Unger, J., Karsbøl, J., Hansen, T., & Bain, S. (2017). Efficacy and safety of once-weekly semaglutide monotherapy versus placebo in patients with type 2 diabetes (SUSTAIN 1): a double-blind, randomised, placebo-controlled, parallel-group, multinational, multicentre phase 3a trial. The Lancet Diabetes & Endocrinology, 5(4), 251-260.
https://doi.org/10.1016/s2213-8587(17)30013-x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa31739
Bain, S., Druyts, E., Balijepalli, C., Baxter, C., Currie, C., Das, R., Donnelly, R., Khunti, K., Langerman, H., Leigh, P., Siliman, G., Thorlund, K., Toor, K., Vora, J., & Mills, E. (2017). Cardiovascular events and all-cause mortality associated with sulfonylureas compared to other antihyperglycaemic drugs: A Bayesian meta-analysis of survival data. Diabetes, Obesity and Metabolism, 19(3), 329-335.
https://doi.org/10.1111/dom.12821, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa31167
Parsons, S., Luzio, S., Bain, S., Harvey, J., McKenna, J., Khan, A., Rice, S., Watkins, A., Owens, D., & Bain, S. (2017). Self-monitoring of Blood Glucose in Non-Insulin Treated Type 2 Diabetes (The SMBG Study): study protocol for a randomised controlled trial. BMC Endocrine Disorders, 17(1)
https://doi.org/10.1186/s12902-017-0154-x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa32118
Kropff, J., Choudhary, P., Neupane, S., Barnard, K., Bain, S., Kapitza, C., Forst, T., Link, M., Dehennis, A., & DeVries, J. (2017). Accuracy and Longevity of an Implantable Continuous Glucose Sensor in the PRECISE Study: A 180-Day, Prospective, Multicenter, Pivotal Trial. Diabetes Care, 40(1), dc161525
https://doi.org/10.2337/dc16-1525, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30843
Kumar, A., Awata, T., Bain, S., Ceriello, A., Fulcher, G., Unnikrishnan, A., Arechavaleta, R., Gonzalez-Gálvez, G., Hirose, T., Home, P., Kaku, K., Litwak, L., Madsbad, S., Pinget, M., Mehta, R., Mithal, A., Tambascia, M., Tibaldi, J., Christiansen, J., & Bain, S. (2016). Clinical use of the co-formulation of insulin degludec and insulin aspart. International Journal of Clinical Practice, 70(8), 657-667.
https://doi.org/10.1111/ijcp.12821, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27110
Marso, S., Bain, S., Consoli, A., Eliaschewitz, F., Jódar, E., Leiter, L., Lingvay, I., Rosenstock, J., Seufert, J., Warren, M., Woo, V., Hansen, O., Holst, A., Pettersson, J., & Vilsbøll, T. (2016). Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes. New England Journal of Medicine, 375, 1834-1844.
https://doi.org/10.1056/NEJMoa1607141, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30129
Evans, P., Bain, S., & Bain, S. (2016). Omarigliptin for the treatment of type 2 diabetes mellitus. Expert Opinion on Pharmacotherapy, 17(14), 1947-1952.
https://doi.org/10.1080/14656566.2016.1218472, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30131
Bain, S., Feher, M., Russell-Jones, D., Khunti, K., & Bain, S. (2016). Management of type 2 diabetes: the current situation and key opportunities to improve care in the UK. Diabetes, Obesity and Metabolism
https://doi.org/10.1111/dom.12760, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30130
Petrie, J., Marso, S., Bain, S., Franek, E., Jacob, S., Masmiquel, L., Leiter, L., Haluzik, M., Satman, I., Omar, M., Shestakova, M., Van Gaal, L., Mann, J., Baeres, F., Zinman, B., Poulter, N., & Bain, S. (2016). LEADER-4. Journal of Hypertension, 34(6), 1140-1150.
https://doi.org/10.1097/HJH.0000000000000890, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26029
Turner, D., Gray, B., Luzio, S., Dunseath, G., Bain, S., Hanley, S., Richards, A., Rhydderch, D., Ayles, M., Kilduff, L., Campbell, M., West, D., & Bracken, R. (2016). Similar magnitude of post-exercise hyperglycemia despite manipulating resistance exercise intensity in type 1 diabetes individuals. Scandinavian Journal of Medicine & Science in Sports, 26(4), 404-412.
https://doi.org/10.1111/sms.12472, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa20927
E, F., GEHM, R., Orsted, D., Mota, M., Jacob, S., Baeres, F., Bain, S., Vidal, J., Haluzik, M., & Bain, S. (2016). Leader 8: Type 2 Diabetes Patients: A Comparison of Baseline Characteristics of Eastern and Western European Participants with Established Cardiovascular Disease in the LEADER Trial. Journal of Diabetes & Metabolism, 07(02)
https://doi.org/10.4172/2155-6156.1000646, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26027
Masmiquel, L., Leiter, L., Vidal, J., Bain, S., Petrie, J., Franek, E., Raz, I., Comlekci, A., Jacob, S., van Gaal, L., Baeres, F., Marso, S., Eriksson, M., & Bain, S. (2016). LEADER 5: prevalence and cardiometabolic impact of obesity in cardiovascular high-risk patients with type 2 diabetes mellitus: baseline global data from the LEADER trial. Cardiovascular Diabetology, 15(1)
https://doi.org/10.1186/s12933-016-0341-5, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25945
Heise, T., Bain, S., Bracken, R., Zijlstra, E., Nosek, L., Stender‐Petersen, K., Rabøl, R., Rowe, E., & Haahr, H. (2016). Similar risk of exercise‐related hypoglycaemia for insulin degludec to that for insulin glargine in patients with type 1 diabetes: a randomized cross‐over trial. Diabetes, Obesity and Metabolism, 18(2), 196-199.
https://doi.org/10.1111/dom.12588, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27008
http://dx.doi.org/10.1111/dom.12588
Davies, M., Bain, S., Atkin, S., Rossing, P., Scott, D., Shamkhalova, M., Bosch-Traberg, H., Syrén, A., Umpierrez, G., & Bain, S. (2016). Efficacy and Safety of Liraglutide Versus Placebo as Add-on to Glucose-Lowering Therapy in Patients With Type 2 Diabetes and Moderate Renal Impairment (LIRA-RENAL): A Randomized Clinical Trial. Diabetes Care, 39(2), 222-230.
https://doi.org/10.2337/dc14-2883, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25946
Turner, D., Luzio, S., Gray, B., Dunseath, G., Rees, E., Kilduff, L., Campbell, M., West, D., Bain, S., Bracken, R., Kilduff, L., Bracken, R., Bain, S., Dunseath, G., & Luzio, S. (2014). Impact of single and multiple sets of resistance exercise in type 1 diabetes. Scandinavian Journal of Medicine & Science in Sports, n/a-n/a.
https://doi.org/10.1111/sms.12202, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa18537
Turner, D., Luzio, S., Kilduff, L., Gray, B., Dunseath, G., Bain, S., Campbell, M., West, D., Bracken, R., Kilduff, L., Bracken, R., Bain, S., Dunseath, G., & Luzio, S. (2014). Reductions in resistance exercise-induced hyperglycaemic episodes are associated with circulating interleukin-6 in Type 1 diabetes. Diabetic Medicine, 31(8), 1009-1013.
https://doi.org/10.1111/dme.12462, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa18538
Campbell, M., West, D., Bain, S., Kingsley, M., Foley, P., Kilduff, L., Turner, D., Gray, B., Stephens, J., Bracken, R., Kilduff, L., Bracken, R., Stephens, J., & Bain, S. (2014). Simulated games activity vs continuous running exercise: A novel comparison of the glycemic and metabolic responses in T1DM patients. Scandinavian Journal of Medicine & Science in Sports, n/a-n/a.
https://doi.org/10.1111/sms.12192, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa19808
Vora, J., Christensen, T., Rana, A., & Bain, S. (2014). Insulin Degludec Versus Insulin Glargine in Type 1 and Type 2 Diabetes Mellitus: A Meta-Analysis of Endpoints in Phase 3a Trials. Diabetes Therapy, 5(2), 435-446.
https://doi.org/10.1007/s13300-014-0076-9, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa20199
Rosenstock, J., Rodbard, H., Bain, S., D’Alessio, D., Seufert, J., Thomsen, A., Svendsen, C., DeVries, J., & Bain, S. (2013). One-year sustained glycemic control and weight reduction in type 2 diabetes after addition of liraglutide to metformin followed by insulin detemir according to HbA1c target. Journal of Diabetes and its Complications, 27(5), 492-500.
https://doi.org/10.1016/j.jdiacomp.2013.04.008, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa16197
Mathieu, C., Hollander, P., Miranda-Palma, B., Cooper, J., Franek, E., Russell-Jones, D., Larsen, J., Tamer, S., Bain, S., & Bain, S. (2013). Efficacy and Safety of Insulin Degludec in a Flexible Dosing Regimen vs Insulin Glargine in Patients With Type 1 Diabetes (BEGIN: Flex T1): A 26-Week Randomized, Treat-to-Target Trial With a 26-Week Extension. Journal of Clinical Endocrinology & Metabolism, 98(3), 1154-1162.
https://doi.org/10.1210/jc.2012-3249, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa16198
DeVries, J., Bain, S., Rodbard, H., Seufert, J., D'Alessio, D., Thomsen, A., Zychma, M., Rosenstock, J., & Bain, S. (2012). Sequential Intensification of Metformin Treatment in Type 2 Diabetes With Liraglutide Followed by Randomized Addition of Basal Insulin Prompted by A1C Targets. Diabetes Care, 35(7), 1446-1454.
https://doi.org/10.2337/dc11-1928, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10748
Mehers, K., Long, A., Slik, A., Aitken, R., Nathwani, V., Wong, F., Bain, S., Gill, G., Roep, B., Bingley, P., Gillespie, K., & Bain, S. (2011). An increased frequency of NK cell receptor and HLA-C group 1 combinations in early-onset type 1 diabetes. Diabetologia, 54(12), 3062-3070.
https://doi.org/10.1007/s00125-011-2299-x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10317
WEST, D., MORTON, R., Stephens, J., BAIN, S., Kilduff, L., LUZIO, S., STILL, R., Bracken, R., Bain, S., & Luzio, S. (2011). Isomaltulose Improves Postexercise Glycemia by Reducing CHO Oxidation in T1DM. Medicine & Science in Sports & Exercise, 43(2), 204
https://doi.org/10.1249/MSS.0b013e3181eb6147, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa9799
Prior, S., Gable, D., Cooper, J., Bain, S., Hurel, S., Humphries, S., Stephens, J., & Bain, S. (2009). Association between the adiponectin promoter rs266729 gene variant and oxidative stress in patients with diabetes mellitus. European Heart Journal, 30(10), 1263
https://doi.org/10.1093/eurheartj/ehp090, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa9796
Savage, D., Patterson, C., Deloukas, P., Whittaker, P., McKnight, A., Morrison, J., Boulton, A., Demaine, A., Marshall, S., Millward, B., Thomas, S., Viberti, G., Walker, J., Sadlier, D., Maxwell, A., Bain, S., & Bain, S. (2008). Genetic association analyses of non-synonymous single nucleotide polymorphisms in diabetic nephropathy. Diabetologia, 51(11), 1998-2002.
https://doi.org/10.1007/s00125-008-1142-5, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa9798
Daousi, C., Bain, S., Barnett, A., Gill, G., & Bain, S. (2008). Hypertriglyceridaemia is associated with an increased likelihood of albuminuria in extreme duration (> 50 years) Type 1 diabetes. Diabetic Medicine, 25(10), 1234
https://doi.org/10.1111/j.1464-5491.2008.02534.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa9797
Barnett, A., Bain, S., Bouter, P., Karlberg, B., Madsbad, S., Jervell, J., Mustonen, J., & Bain, S. (2004). Angiotensin-Receptor Blockade versus Converting–Enzyme Inhibition in Type 2 Diabetes and Nephropathy. New England Journal of Medicine, 351(19), 1952-1961.
https://doi.org/10.1056/NEJMoa042274, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1340
Gillespie, K., Bain, S., Barnett, A., Bingley, P., Christie, M., Gill, G., Gale, E., & Bain, S. (2004). The rising incidence of childhood type 1 diabetes and reduced contribution of high-risk HLA haplotypes. The Lancet, 364(9446), 1699-1700.
https://doi.org/10.1016/S0140-6736(04)17357-1, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1341
Amer, S. & Bain, S. (n.d.) Sleep disturbance due to hand discomfort. Diabetic Medicine
https://doi.org/10.1111/dme.15330, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65983
http://dx.doi.org/10.1111/dme.15330
Seidu, S., Alabraba, V., Davies, S., Newland-Jones, P., Fernando, K., Bain, S., Diggle, J., Evans, M., James, J., Kanumilli, N., Milne, N., Viljoen, A., Wheeler, D., & Wilding, J. (n.d.) SGLT2 Inhibitors – The New Standard of Care for Cardiovascular, Renal and Metabolic Protection in Type 2 Diabetes: A Narrative Review. Diabetes Therapy
https://doi.org/10.1007/s13300-024-01550-5, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65982
http://dx.doi.org/10.1007/s13300-024-01550-5
Chowdhury, S., Sadouki, F., Collins, E., Keen, F., Bhagi, R., Lim, Y., Cozma, S., & Bain, S. (n.d.) Real-World Use of Oral and Subcutaneous Semaglutide in Routine Clinical Practice in the UK: A Single-Centre, Retrospective Observational Study. Diabetes Therapy
https://doi.org/10.1007/s13300-024-01551-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65730
http://dx.doi.org/10.1007/s13300-024-01551-4

Other Research Outputs

Bain, S. (2020). Lowering of Hemoglobin A1C and Risk of Cardiovascular Outcomes and All-Cause Mortality, A Meta-Regression Analysis [Expert Comment on article published in: Journal of Diabetes and Its Complications 2020 Jul 31;[EPub Ahead of Print], M Fralick, M Colacci, A Odutayo, R Siemieniuk, RJ Glynne]
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55061
https://www.practiceupdate.com/content/lowering-of-hemoglobin-a1c-and-risk-of-cardiovascular-outcomes/104435/65/8/1

Supervision

Acute Kidney Injury in Wales (awarded 2023)

MD

Other supervisor: Prof Ronan Lyons
Swansea Stroke Scale (SSS) for bedside assessment of Stroke sufferers by non-specialists (current)

PhD

Other supervisor: Dr Roderick Thomas
An investigation of Continuous Glucose Monitoring and Glycaemic management in an athletic cohort and its potential impact on exercise performance. (current)

PhD

Other supervisor: Prof Richard Bracken
Characterising the aerobic exercise-induced glycaemic response in individuals with type 1 diabetes using insulin Fiasp and Aspart (current)

PhD

Other supervisor: Prof Richard Bracken
Furthering the understanding of interstitial glucose on ECG metrics in people with type 1 diabetes. (awarded 2023)

MSc

Other supervisor: Prof Richard Bracken

Taught Modules

PM-344 Capstone Project

The aim of this module is to provide a capstone experience to students¿ learning, through participating in their own enquiry-based research project, with guidance from an academic supervisor. The project may be laboratory or non-laboratory based, but it will always involve a research question that is drawn from the literature, and focused on a topic relevant to the life sciences. It will ask a research question and involve the critical analysis of research findings. Students will refine their oral and written communication skills to a graduate level through an oral presentation and dissertation on their research findings and conclusions.
PM-356 The Sweet Sickness: Advances in Diabetes and Related Disorders

7% of the population suffers from diabetes. This prevalence is set to rise with an ageing population and increasing rates of obesity. The problem is especially acute in Wales, where over half the adult population is obese. According to Diabetes Wales, there are 177,000 people in the country living with diabetes, and estimates suggest a further 70,000 people have diabetes but are either unaware or have no confirmed diagnosis. If current trends continue, by 2025, it is estimated that 300,000 people in Wales will have diabetes. This module will provide an overview of diabetes and the public health challenges it presents. The world-leading research of the Diabetes Research Group, located here at Swansea University Medical School, will be a particular focus with basic, clinical, epidemiological, social care and health services research discussed.
PMDM05 Diabetes Management II

This module is delivered primarily as a 5-day residential that aims to enhance the students¿ knowledge of the advanced treatments for diabetes. It will explore continuous/flash glucose monitoring and all aspects of pump technologies and pregnancy usage. This will enable the students to see and handle these new technologies that are not necessarily common place in clinics, and appreciate the concept of treatment planning and progression using these devices. The module will be delivered primarily on campus (5-day residential) with extra online content, and both in situ and online assessments.
PMDM101 Diabetic Practice

Diabetes has reached world wide epidemic proportions and is fast becoming the defining disease of the 21st century. It also represents a major challenge to health organizations in chronic disease management. This module provides the basis for health care professionals to deliver high quality multidisciplinary diabetes care is an accredited qualification in Diabetes Care from the Swansea University. The module enables students to extend their network of contacts with others working in diabetes care, share experiences and develop supportive relationships.
PMZM17 Diabetes Management II

This core module is delivered as a 5-day residential that aims to enhance the students¿ knowledge of the advanced treatments for diabetes. It will explore continuous/flash glucose monitoring and all aspects of pump technologies and pregnancy usage. This will enable the students to see and handle these new technologies that are not necessarily common place in clinics, and appreciate the concept of treatment planning and progression using these devices. This module will be delivered through via a 5 day residential.
PMZM18 Diabetic Practice

Diabetes has reached world wide epidemic proportions and is fast becoming the defining disease of the 21st century. It also represents a major challenge to health organizations in chronic disease management. This module provides the basis for health care professionals to deliver high quality multidisciplinary diabetes care is an accredited qualification in Diabetes Care from the Swansea University. The module enables students to extend their network of contacts with others working in diabetes care, share experiences and develop supportive relationships.

Professor Steve Bain

Telephone number

Email address