Dr Sanjiv Sharma

Uwch-ddarlithydd mewn Peirianneg Feddygol, Biomedical Engineering

sanjiv.sharma@abertawe.ac.uk

420
Pedwerydd Llawr
Adeilad Gogleddol Peirianneg
Campws y Bae

Ar gael ar gyfer Goruchwyliaeth Ôl-raddedig

Dolenni Ymchwil

https://orcid.org/0000-0003-3828-737X

Google Scholar

ResearcherID

Trosolwg

Derbyniodd Dr Sanjiv Sharma ei PhD am ymchwil ar ddatblygu dulliau dadansoddol ar gyfer penderfynu ar rai cynhyrchion fferyllol a'u metabolion gan ddefnyddio system wahanu fychanedig yn 2001. Roedd ei PhD, wedi’i oruchwylio gan Dr Sunil Kumar Sanghi, yn rhan o brosiect ymchwil Indo-Ewropeaidd ar y cyd ar system wahanu fychanedig mewn cydweithrediad â Phrifysgol Amsterdam. Yna fe wnaeth ymchwil ôl-ddoethurol ym meysydd dilyniannu trwybwn uchel, proteomeg glinigol a systemau dadansoddol bychanedig yn Ffrainc a'r Almaen rhwng 2001 a 2004. Yn 2004, dyfarnwyd Cymrodoriaeth Technoleg Chevening iddo i weithio gyda'r Athro Andrew deMello ar systemau microadwaith microhylifol yn yr Adran Gemeg yng Ngholeg Imperial Llundain.

Ar ôl cwblhau ei gymrodoriaeth ymunodd â'r Sefydliad Peirianneg Biofeddygol, Coleg Imperial Llundain i weithio gyda'r Athro Tony Cass ym maes Bionanotechnoleg a Biosynwyryddion. Yma datblygodd ficronodwyddau minimol fewnwthiol, o wnethuriad ffotolithograffig i wneuthuriad trwybwn uchel, gan fynd â'r micronodwyddau hyn o'r labordy i'r clinig. Roedd Sanjiv yn rhan o brosiect ymchwil a ariannwyd gan NIHR (i4i) a oedd yn cynnwys astudiaethau clinigol mewn gwirfoddolwyr iach a chyfranogwyr gyda T1D gyda Chlinigwyr Endocrinoleg enwog: Yr Athro Desmond Johnston a'r Athro Nick Oliver. Mae wedi cyhoeddi dros 50 o erthyglau ymchwil ac mae ganddo batentau wedi'u ffeilio yn yr Almaen, y DU a'r Unol Daleithiau.

Ar hyn o bryd mae Sanjiv yn Uwch Ddarlithydd mewn Peirianneg Feddygol yng Ngholeg Peirianneg Prifysgol Abertawe. Yn Abertawe, mae'n gweithio ar ddarparu cyffuriau therapiwtig a chymwysiadau diagnostig (theranostig) micronodwyddau polymerig.

Meysydd Arbenigedd

Micronodwyddau
Synwyryddion minimol fewnwthiol
Monitro glwcos parhaus (CGM)
Monitro lactos parhaus (CLM)
Monitro cyffuriau therapiwtig interstitaidd (iTDM)

Cyhoeddiadau

Uchafbwyntiau Ymchwil

Rawson, T., Gowers, S., Freeman, D., Wilson, R., Sharma, S., Gilchrist, M., MacGowan, A., Lovering, A., Bayliss, M., Kyriakides, M., Georgiou, P., Cass, A., O'Hare, D., & Holmes, A. (2019). Microneedle biosensors for real-time, minimally invasive drug monitoring of phenoxymethylpenicillin: a first-in-human evaluation in healthy volunteers. The Lancet Digital Health, 1(7), e335-e343.
https://doi.org/10.1016/s2589-7500(19)30131-1, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51460
http://dx.doi.org/10.1016/s2589-7500(19)30131-1
Bollella, P., Sharma, S., Cass, A., Tasca, F., & Antiochia, R. (2019). Minimally Invasive Glucose Monitoring Using a Highly Porous Gold Microneedles-Based Biosensor: Characterization and Application in Artificial Interstitial Fluid. Catalysts, 9(7), 580
https://doi.org/10.3390/catal9070580, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa50906
Guy, O., Sharma, S., Howells, O., Rajendran, N., Mcintyre, S., Amini-Asl, S., Henri, P., Liu, Y., Guy, O., Cass, A., & Morris, M. (2019). Microneedle array‐based platforms for future theranostic applications. ChemBioChem
https://doi.org/10.1002/cbic.201900112, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa49693
Sharma, S. (2019). Recent Developments in Continuous Monitoring Diagnostics with Microneedle Arrays. In 7th International Conference on the Development of Biomedical Engineering in Vietnam (BME7)BME7 Conference.
https://doi.org/10.1007/978-981-13-5859-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48663
Bollella, P., Sharma, S., Cass, A., & Antiochia, R. (2019). Minimally-invasive Microneedle-based Biosensor Array for Simultaneous Lactate and Glucose Monitoring in Artificial Interstitial Fluid. Electroanalysis, 31(2), 374-382.
https://doi.org/10.1002/elan.201800630, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48159
Bollella, P., Sharma, S., Cass, A., & Antiochia, R. (2019). Microneedle-based biosensor for minimally-invasive lactate detection. Biosensors and Bioelectronics, 123, 152-159.
https://doi.org/10.1016/j.bios.2018.08.010, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa43849
Sharma, S., El-Laboudi, A., Reddy, M., Jugnee, N., Sivasubramaniyam, S., Sharkawy, M., Georgiou, P., Johnston, D., Oliver, N., & Cass, A. (2018). A pilot study in humans of microneedle sensor arrays for continuous glucose monitoring. Analytical Methods, 10(18), 2088-2095.
https://doi.org/10.1039/C8AY00264A, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa39114
Rawson, T., O’Hare, D., Herrero, P., Sharma, S., Moore, L., Barra, E., Roberts, J., Gordon, A., Hope, W., Georgiou, P., Cass, A., Holmes, A., & Sharma, S. (2017). Delivering precision antimicrobial therapy through closed-loop control systems. Journal of Antimicrobial Chemotherapy
https://doi.org/10.1093/jac/dkx458, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa37320
https://academic.oup.com/jac/advance-article/doi/10.1093/jac/dkx458/4688914
Ghoreishizadeh, S., Zhang, X., Sharma, S., & Georgiou, P. (2017). Study of Electrochemical Impedance of a Continuous Glucose Monitoring Sensor and its Correlation with Sensor Performance. IEEE Sensors Letters, 1-1.
https://doi.org/10.1109/LSENS.2017.2778248, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa37061
Rawson, T., Sharma, S., Georgiou, P., Holmes, A., Cass, A., & O'Hare, D. (2017). Towards a minimally invasive device for beta-lactam monitoring in humans. Electrochemistry Communications, 82, 1-5.
https://doi.org/10.1016/j.elecom.2017.07.011, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36437
https://spiral.imperial.ac.uk/handle/10044/1/52776

Holl Ymchwil

Erthyglau Cylchgronau

Vulpe, G., Liu, G., Oakley, S., Yang, G., Ajith Mohan, A., Waldron, M., & Sharma, S. (2024). Lab on skin: real-time metabolite monitoring with polyphenol film based subdermal wearable patches. Lab on a Chip, 24(7), 2039-2048.
https://doi.org/10.1039/d4lc00073k, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65673
Rahbari, R., Francis, L., Guy, O., Sharma, S., Ruhland, C., & Xia, Z. (2023). Microneedle-Assisted Transfersomes as a Transdermal Delivery System for Aspirin. Pharmaceutics, 16(1), 57
https://doi.org/10.3390/pharmaceutics16010057, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65386
http://dx.doi.org/10.3390/pharmaceutics16010057
Oliveira, D., Correia, B., Sharma, S., & Moreira, F. (2022). Molecular Imprinted Polymers on Microneedle Arrays for Point of Care Transdermal Sampling and Sensing of Inflammatory Biomarkers. ACS Omega, 7(43), 39039-39044.
https://doi.org/10.1021/acsomega.2c04789, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa61543
Howells, O., Blayney, G., Gualeni, B., Birchall, J., Eng, P., Ashraf, H., Sharma, S., & Guy, O. (2022). Design, fabrication, and characterisation of a silicon microneedle array for transdermal therapeutic delivery using a single step wet etch process. European Journal of Pharmaceutics and Biopharmaceutics, 171, 19-28.
https://doi.org/10.1016/j.ejpb.2021.06.005, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57114
Ali, M., Mitchell, J., Burwell, G., Rejnhard, K., Mitchell, C., Daghigh Ahmadi, E., Sharma, S., & Guy, O. (2021). Application of Molecular Vapour Deposited Al2O3 for Graphene-Based Biosensor Passivation and Improvements in Graphene Device Homogeneity. Nanomaterials, 11(8), 2121
https://doi.org/10.3390/nano11082121, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa58054
An, J., Chen, M., Liu, G., Hu, Y., Chen, R., Lyu, Y., Sharma, S., & Liu, Y. (2021). Water-stable perovskite-on-polymer fluorescent microspheres for simultaneous monitoring of pH, urea, and urease. Analytical and Bioanalytical Chemistry, 413(6), 1739-1747.
https://doi.org/10.1007/s00216-020-03144-z, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56139
Bollella, P., Sharma, S., Cass, A., Tasca, F., & Antiochia, R. (2019). Minimally Invasive Glucose Monitoring Using a Highly Porous Gold Microneedles-Based Biosensor: Characterization and Application in Artificial Interstitial Fluid. Catalysts, 9(7), 580
https://doi.org/10.3390/catal9070580, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa50906
Guy, O., Sharma, S., Howells, O., Rajendran, N., Mcintyre, S., Amini-Asl, S., Henri, P., Liu, Y., Guy, O., Cass, A., & Morris, M. (2019). Microneedle array‐based platforms for future theranostic applications. ChemBioChem
https://doi.org/10.1002/cbic.201900112, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa49693
Bollella, P., Sharma, S., Cass, A., & Antiochia, R. (2019). Minimally-invasive Microneedle-based Biosensor Array for Simultaneous Lactate and Glucose Monitoring in Artificial Interstitial Fluid. Electroanalysis, 31(2), 374-382.
https://doi.org/10.1002/elan.201800630, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48159
Bollella, P., Sharma, S., Cass, A., & Antiochia, R. (2019). Microneedle-based biosensor for minimally-invasive lactate detection. Biosensors and Bioelectronics, 123, 152-159.
https://doi.org/10.1016/j.bios.2018.08.010, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa43849
Rawson, T., Gowers, S., Freeman, D., Wilson, R., Sharma, S., Gilchrist, M., MacGowan, A., Lovering, A., Bayliss, M., Kyriakides, M., Georgiou, P., Cass, A., O'Hare, D., & Holmes, A. (2019). Microneedle biosensors for real-time, minimally invasive drug monitoring of phenoxymethylpenicillin: a first-in-human evaluation in healthy volunteers. The Lancet Digital Health, 1(7), e335-e343.
https://doi.org/10.1016/s2589-7500(19)30131-1, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51460
http://dx.doi.org/10.1016/s2589-7500(19)30131-1
Sharma, S., El-Laboudi, A., Reddy, M., Jugnee, N., Sivasubramaniyam, S., Sharkawy, M., Georgiou, P., Johnston, D., Oliver, N., & Cass, A. (2018). A pilot study in humans of microneedle sensor arrays for continuous glucose monitoring. Analytical Methods, 10(18), 2088-2095.
https://doi.org/10.1039/C8AY00264A, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa39114
Rawson, T., O’Hare, D., Herrero, P., Sharma, S., Moore, L., Barra, E., Roberts, J., Gordon, A., Hope, W., Georgiou, P., Cass, A., Holmes, A., & Sharma, S. (2017). Delivering precision antimicrobial therapy through closed-loop control systems. Journal of Antimicrobial Chemotherapy
https://doi.org/10.1093/jac/dkx458, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa37320
https://academic.oup.com/jac/advance-article/doi/10.1093/jac/dkx458/4688914
Ghoreishizadeh, S., Zhang, X., Sharma, S., & Georgiou, P. (2017). Study of Electrochemical Impedance of a Continuous Glucose Monitoring Sensor and its Correlation with Sensor Performance. IEEE Sensors Letters, 1-1.
https://doi.org/10.1109/LSENS.2017.2778248, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa37061
Rawson, T., Sharma, S., Georgiou, P., Holmes, A., Cass, A., & O'Hare, D. (2017). Towards a minimally invasive device for beta-lactam monitoring in humans. Electrochemistry Communications, 82, 1-5.
https://doi.org/10.1016/j.elecom.2017.07.011, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36437
https://spiral.imperial.ac.uk/handle/10044/1/52776
Sharma, S., Saeed, A., Johnson, C., Gadegaard, N., & Cass, A. (2017). Rapid, low cost prototyping of transdermal devices for personal healthcare monitoring. Sensing and Bio-Sensing Research, 13, 104-108.
https://doi.org/10.1016/j.sbsr.2016.10.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36253
Sharma, S., Huang, Z., Rogers, M., Boutelle, M., & Cass, A. (2016). Evaluation of a minimally invasive glucose biosensor for continuous tissue monitoring. Analytical and Bioanalytical Chemistry, 408(29), 8427-8435.
https://doi.org/10.1007/s00216-016-9961-6, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36255
Perevedentsev, A., Sonnefraud, Y., Belton, C., Sharma, S., Cass, A., Maier, S., Kim, J., Stavrinou, P., & Bradley, D. (2015). Dip-pen patterning of poly(9,9-dioctylfluorene) chain-conformation-based nano-photonic elements. Nature Communications, 6(1), 5977
https://doi.org/10.1038/ncomms6977, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36439
Moreira, F., Sharma, S., Dutra, R., Noronha, J., Cass, A., & Sales, M. (2015). Detection of cardiac biomarker proteins using a disposable based on a molecularly imprinted polymer grafted onto graphite. Microchimica Acta, 182(5-6), 975-983.
https://doi.org/10.1007/s00604-014-1409-0, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36614
Le, T., Adamiak, B., Benton, D., Johnson, C., Sharma, S., Fenton, R., McCauley, J., Iqbal, M., & Cass, A. (2014). Aptamer-based biosensors for the rapid visual detection of flu viruses. Chem. Commun., 50(98), 15533-15536.
https://doi.org/10.1039/C4CC07888H, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36440
http://pubs.rsc.org/-/content/articlelanding/2014/cc/c4cc07888h/unauth#!divAbstract
Moreira, F., Sharma, S., Dutra, R., Noronha, J., Cass, A., & Sales, M. (2014). Protein-responsive polymers for point-of-care detection of cardiac biomarker. Sensors and Actuators B: Chemical, 196, 123-132.
https://doi.org/10.1016/j.snb.2014.01.038, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36442
http://www.sciencedirect.com/science/article/pii/S0925400514000550
El-Laboudi, A., Sharma, S., Oliver, N., Cass, A., Johnston, D., & Sharma, S. (2013). DEVELOPMENT OF A NOVEL MICROPROBE ARRAY CONTINUOUS GLUCOSE MONITOR: MECHANICAL CHARACTERIZATION. Diabetes Technology & Therapeutics, 15
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36455
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000315467200165&KeyUID=WOS:000315467200165
Salehi-Reyhani, A., Sharma, S., Burgin, E., Barclay, M., Cass, A., Neil, M., Ces, O., Willison, K., & Klug, D. (2013). Scaling advantages and constraints in miniaturized capture assays for single cell protein analysis. Lab on a Chip, 13(11), 2066
https://doi.org/10.1039/C3LC41388H, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36443
http://pubs.rsc.org/-/content/articlelanding/2013/lc/c3lc41388h/unauth#!divAbstract
Moreira, F., Sharma, S., Dutra, R., Noronha, J., Cass, A., & Sales, M. (2013). Smart plastic antibody material (SPAM) tailored on disposable screen printed electrodes for protein recognition: Application to myoglobin detection. Biosensors and Bioelectronics, 45, 237-244.
https://doi.org/10.1016/j.bios.2013.02.012, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36444
http://www.sciencedirect.com/science/article/pii/S0956566313001103
Trzebinski, J., Sharma, S., Radomska-Botelho Moniz, A., Michelakis, K., Zhang, Y., & Cass, A. (2012). Microfluidic device to investigate factors affecting performance in biosensors designed for transdermal applications. Lab Chip, 12(2), 348-352.
https://doi.org/10.1039/C1LC20885C, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36258
http://pubs.rsc.org/en/content/articlelanding/2012/lc/c1lc20885c#!divAbstract
Sharma, S., Michelakis, K., Cass, A., Intisar, E., Santhanam, H., Salehi-Reyhani, A., Bahrami, A., & Sharma, S. (2012). Method for fabricating nanostructures via nanotemplates using dip-pen nanolithography. Micro & Nano Letters, 7(10), 1038-1040.
https://doi.org/10.1049/mnl.2012.0698, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36446
http://digital-library.theiet.org/content/journals/10.1049/mnl.2012.0698
Moniz, A., Michelakis, K., Trzebinski, J., Sharma, S., Johnston, D., Oliver, N., & Cass, A. (2012). Minimally Invasive Enzyme Microprobes: An Alternative Approach for Continuous Glucose Monitoring. Journal of Diabetes Science and Technology, 6(2), 479-480.
https://doi.org/10.1177/193229681200600239, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36447
http://journals.sagepub.com/doi/metrics/10.1177/193229681200600239#articleCitationDownloadContainer
Trzebinski , J., Moniz, A., Sharma, S., Burugapalli, K., Moussy, F., & Cass, A. (2011). Hydrogel Membrane Improves Batch-to-Batch Reproducibility of an Enzymatic Glucose Biosensor. Electroanalysis, 23(12), 2789-2795.
https://doi.org/10.1002/elan.201100286, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36259
Azarbadegan, A., Eames, I., Sharma, S., Cass, A., & Sharma, S. (2011). Computational study of parallel valveless micropumps. Sensors and Actuators B: Chemical, 158(1), 432-440.
https://doi.org/10.1016/j.snb.2011.04.085, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36448
http://www.sciencedirect.com/science/article/pii/S0925400511003820
Sharma, S., Moniz, A., Triantis, I., Michelakis, K., Trzebinski, J., Azarbadegan, A., Field, B., Toumazou, C., Eames, I., & Cass, A. (2010). An integrated silicon sensor with microfluidic chip for monitoring potassium and pH. Microfluidics and Nanofluidics, 10(5), 1119-1125.
https://doi.org/10.1007/s10404-010-0740-y, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36449
https://link.springer.com/article/10.1007/s10404-010-0740-y
Winkle, R., Nagy, J., Cass, A., & Sharma, S. (2008). Towards microfluidic technology-based MALDI-MS platforms for drug discovery: a review. Expert Opinion on Drug Discovery, 3(11), 1281-1292.
https://doi.org/10.1517/17460441.3.11.1281, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36450
http://www.tandfonline.com/doi/abs/10.1517/17460441.3.11.1281
Huebner, A., Sharma, S., Srisa-Art, M., Hollfelder, F., Edel, J., & deMello, A. (2008). Microdroplets: A sea of applications?. Lab on a Chip, 8(8), 1244
https://doi.org/10.1039/B806405A, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36451
http://pubs.rsc.org/en/content/articlelanding/2008/lc/b806405a/unauth#!divAbstract
Sharma, S., Buchholz, K., Luber, S., Rant, U., Tornow, M., Abstreiter, G., & Sharma, S. (2006). Silicon-on-Insulator Microfluidic Device With Monolithic Sensor Integration for<tex>$murm TAS$</tex>Applications. Journal of Microelectromechanical Systems, 15(2), 308-313.
https://doi.org/10.1109/JMEMS.2006.872222, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36452
http://ieeexplore.ieee.org/abstract/document/1618715/?reload=true
Bruneel, A., Labas, V., Mailloux, A., Sharma, S., Royer, N., Vinh, J., Pernet, P., Vaubourdolle, M., & Baudin, B. (2005). Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis. PROTEOMICS, 5(15), 3876-3884.
https://doi.org/10.1002/pmic.200401239, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36453
http://onlinelibrary.wiley.com/doi/10.1002/pmic.200401239/full
Durgbanshi, A., Sharma, S., Shelke, M., Bose, D., Asthana, A., Sanghi, S., & Sharma, S. (2004). Determination of amino acids separated by micellar electrokinetic chromatography after pre-column derivatization with o-phthalaldehyde. Indian Journal of Chemistry Section a-Inorganic Bio-Inorganic Physical Theoretical & Analytical Chemistry, 43
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36612
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000221518400012&KeyUID=WOS:000221518400012
Sharma, S. (2004). Determination of amino acids separated by micellar electrokinetic chromatography after pre-column derivatization with o-phthalaldehyde. Indian Journal of Chemistry Section A
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36609
http://nopr.niscair.res.in/handle/123456789/18149
Sharma, S. (2003). Simultaneous assay of salbutamol sulphate and guaiphenesin in pharmaceutical preparations by microbore column liquid chromatography. Indian Drugs
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36610
Bruneel, A., Labas, V., Mailloux, A., Sharma, S., Vinh, J., Vaubourdolle, M., & Baudin, B. (2003). Proteomic study of human umbilical vein endothelial cells in culture. PROTEOMICS, 3(5), 714-723.
https://doi.org/10.1002/pmic.200300409, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36261
Sharma, S. (2000). Determination of benzodiazepines by reverse phase liquid chromatography. Indian Drugs
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36611
McNamee, M., Wong, S., Guy, O., & Sharma, S. (n.d.) Microneedle technology for potential SARS-CoV-2 vaccine delivery. Expert Opinion on Drug Delivery, 1-16.
https://doi.org/10.1080/17425247.2023.2209718, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63375
http://dx.doi.org/10.1080/17425247.2023.2209718
Correia, B., Oliveira, D., Vulpe, G., Tavares, A., Sales, M., Duarte, A., Sharma, S., & Moreira, F. (n.d.) A cork based substrate coupled with artificial antibodies for point-of-care detection of pro-inflammatory cytokine biomarkers. Sensors & Diagnostics
https://doi.org/10.1039/d3sd00022b, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63391
http://dx.doi.org/10.1039/d3sd00022b

Penodau Llyfrau

Ghoreishizadeh, S. & Sharma, S. (2021). Continuous Glucose Monitoring Sensors for Management of Diabetes. Handbook of Biochips (pp. 1-17). Springer New York
https://doi.org/10.1007/978-1-4614-6623-9_58-1, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57080
http://dx.doi.org/10.1007/978-1-4614-6623-9_58-1
Cass, A. & Sharma, S. (2017). Microneedle Enzyme Sensor Arrays for Continuous In Vivo Monitoring. Enzymes as Sensors (pp. 413-427). Elsevier
https://doi.org/10.1016/bs.mie.2017.02.002, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36254
Sharma, S., Srisa-Art, M., Scott, S., Asthana, A., & Cass, A. (2012). Droplet-Based Microfluidics. Microfluidic Diagnostics (pp. 207-230). Humana Press
https://doi.org/10.1007/978-1-62703-134-9_15, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36257
Srisa-Art, M. & Sharma, S. (2012). Microfluidic Diagnostics. Droplet-Based Microfluidics for Binding Assays and Kinetics Based on FRET (pp. 231-240).
https://doi.org/10.1007/978-1-62703-134-9_16, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36445
Triantis, I., Radomska-Botelho Moniz, A., Michelakis, K., Sharma, S., Trzebinski, J., Garner, B., & Eftekhar, A. (2011). Ionic Neural Sensing. Springer Handbook of Medical Technology (pp. 1059-1072). Springer Berlin Heidelberg
https://doi.org/10.1007/978-3-540-74658-4_56, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36260

Cyfraniadau Cynadleddau

Sharma, S. (2019). Recent Developments in Continuous Monitoring Diagnostics with Microneedle Arrays. In 7th International Conference on the Development of Biomedical Engineering in Vietnam (BME7)BME7 Conference.
https://doi.org/10.1007/978-981-13-5859-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48663
Sharma, S., Takagi, E., Cass, T., Tsugawa, W., & Sode, K. (2017). Minimally Invasive Microneedle Array Electrodes Employing Direct Electron Transfer Type Glucose Dehydrogenase for the Development of Continuous Glucose Monitoring Sensors. In Procedia Technology (pp. 208-209).
https://doi.org/10.1016/j.protcy.2017.04.087, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36438
http://www.sciencedirect.com/science/article/pii/S2212017317300889
Hu, Y., Sharma, S., Weatherwax, J., Cass, A., & Georgiou, P. (2016). Live demonstration: A portable multi-channel potentiostat for real-time amperometric measurement of multi-electrode sensor arrays. (pp. 2373-2373). IEEE.
https://doi.org/10.1109/iscas.2016.7539064, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36256
Sharma, S. (2016). Abstracts from ATTD 2016 9th International Conference on Advanced Technologies & Treatments for DiabetesMilan, Italy–February 3–6, 2016. In Diabetes Technology & Therapeutics (pp. A-1-A-140).
https://doi.org/10.1089/dia.2016.2525, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36605
http://online.liebertpub.com/doi/full/10.1089/dia.2016.2525
Sharma, S. (2015). Abstracts from ATTD 20158th International Conference on Advanced Technologies & Treatments for DiabetesParis, France—February 18–21, 2015. In Diabetes Technology & Therapeutics (pp. A-1-A-180).
https://doi.org/10.1089/dia.2015.1525, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36606
http://online.liebertpub.com/doi/10.1089/dia.2015.1525
Sharma, S. (2014). DEVELOPMENT OF A NOVEL MICROPROBE ARRAY CONTINUOUS GLUCOSE SENSOR FOR TYPE 1 DIABETES: INTERFERENCE STUDIES. In DIABETES TECHNOLOGY & THERAPEUTICS
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36607
Sharma, S. (2013). Development of a novel microprobe array continuous glucose monitor: pre-clinical validation. SPRINGER.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36615
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000329196902278&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Cynnyrch Ymchwil Arall

Sharma, S. (2014). Multi-probe microstructured arrays
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36441
https://patents.google.com/patent/EP3169234A1/en?inventor=Tony+CASS
Sharma, S. (2012). Maskless micro- and nano-templating
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36608
https://patents.google.com/patent/WO2012156732A1/en?q=nanotemplate&inventor=Sanjiv+sharma
Sharma, S. (2005). On-chip integrated detector for analyzing fluids
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36454
https://www.google.com/patents/US20050212016

Goruchwyliaeth

Development of Graphene Based Biosensors for Early Detection of Alzheimer's Disease (dyfarnwyd 2023)

PhD

Goruchwyliwr arall: Dr Zari Tehrani

Goruchwyliwr arall: Prof Owen Guy
Creation and Optimisation of Plasma Etch Processes for the Manufacture of Silicon Microstructures (dyfarnwyd 2023)

PhD

Goruchwyliwr arall: Prof Owen Guy
Microneedles for Theranostics (cyfredol)

PhD

Goruchwyliwr arall: Prof Owen Guy
Development of Microneedles for Diagnostics and Therapeutics (dyfarnwyd 2023)

PhD

Goruchwyliwr arall: Prof Owen Guy
Coated subdermal wearable patches for real time continuous monitoring (cyfredol)

EngD

Goruchwyliwr arall: Prof Keir Lewis
The Development of Silicon Microneedles (cyfredol)

EngD

Goruchwyliwr arall: Dr Hari Arora

Modiwlau a Addysgir

EG-385 Polymers: Properties and Design

To instil an understanding of design methods with polymeric materials, dealing especially with viscoelastic behaviour. ¿ Mechanical properties and design with rubber. ¿ General mechanical properties of polymers; viscoelasticity, time and temperature dependence, creep, recovery and stress relaxation. ¿ Design using deformation data; creep curves, pseudo-elastic design methodology, time and temperature dependant modulus, limiting strain. ¿ Mathematical modelling of viscoelasticity; equations for creep, recovery, relaxation, Maxwell and Voigt models, 4-element model, standard linear solid model. ¿ Boltzmann superposition principle and its use with complex stress histories. ¿ Strength and fracture of polymers; energy approach, toughness, ductile / brittle transitions, yield strength, ductility factor. ¿ Creep failure of plastics; fracture mechanics approach, fatigue failure, effects of cycle frequency, waveform, fracture mechanics approach to fatigue.
EGA109 Chemistry for Engineers

The module introduces the basic principles of chemistry to Engineers. It covers a wide range of topics ranging from reactions in organic and inorganic compounds to the physicochemical properties of compounds. We will also explore the principles of thermodynamics and chemical kinetics in chemical reactions.
EGDM03 Individual Research Design Project

This module involves the application of advanced scientific and engineering principles to the solution of a practical problem coming from outside engineering. It mainly involves project to design solutions for complex biomedical engineering problems and evidences some originality and meets a combination of societal, user, business and customer needs as appropriate. This project will involve consideration of applicable health and safety, diversity, inclusion, cultural, societal, environmental and commercial matters, codes of practice and industry standards. The student will be working independently on a substantial, individually assigned research design, using accepted planning procedures. It will require and develop self-organisation and a critical evaluation of options and results, as well as developing technical knowledge in the topic of research design. The student will develop a clear view on the integration of biomedical engineering in a professional environment.
EGM403 Implant Engineering 2

This module is an advanced look at the design, fabrication and optimisation of medical implants and prosthetics. Case studies will be used to bring together engineering concepts and apply them to key devices that are used to treat disease and assist patients.
EGNM07 Principles of Nanomedicine

This module will cover the broad range of subjects which encompass the discipline nanomedicine. Building on the foundation of a knowledge of nanotechnology this module will focus on medical applications including biological markers, diagnostics, therapeutics and drug delivery vehicles.
EGTM89 Polymers: Properties and Design

To instil an understanding of design methods with polymeric materials, dealing especially with viscoelastic behaviour. ¿ Mechanical properties and design with rubber. ¿ General mechanical properties of polymers; viscoelasticity, time and temperature dependence, creep, recovery and stress relaxation. ¿ Design using deformation data; creep curves, pseudo-elastic design methodology, time and temperature dependant modulus, limiting strain. ¿ Mathematical modelling of viscoelasticity; equations for creep, recovery, relaxation, Maxwell and Voigt models, 4-element model, standard linear solid model. ¿ Boltzmann superposition principle and its use with complex stress histories. ¿ Strength and fracture of polymers; energy approach, toughness, ductile / brittle transitions, yield strength, ductility factor. ¿ Creep failure of plastics; fracture mechanics approach, fatigue failure, effects of cycle frequency, waveform, fracture mechanics approach to fatigue.

Cyflwyniadau, Darlithoedd a Chynadleddau a wahoddwyd

Continuous monitoring diagnostics with microneedle arrays

2019

Prifysgol Montpelier, Ffrainc
Microneedles for Interstitial Fluid Physiology

Tachwedd 2019

Cyfarfod Technoleg Diabetes
Development of a minimally invasive continuous lactate monitoring sensor for clinical and sports applications

Mehefin 2019

BioSensing Tech
Towards a fully scalable minimally invasive, continuous glucose monitoring sensor, Type 1 diabetes

Mehefin 2018

Cyngres Biosynwyryddion y Byd
Microneedle array-based platform for future theranostic applications

Mehefin 2018

28fed Cyngres Biosynwyryddion y Byd - UDA
Minimally invasive, continuous glucose monitoring in human subjects

Mai 2017

5ed Gyngres Ryngwladol ar Dechnolegau Bio-Synhwyro

Grantiau a Phrosiectau Allweddol

Dyfeisiau brechu clyfar ar gyfer heintiau COVID-19 2020 - 2021

Llywodraeth Cymru, £99,538.15
Ysgoloriaethau PhD Sgiliau'r Economi Wybodaeth (KESS) (2) 2018 - 2021

Llywodraeth Cymru a Chronfeydd Cymdeithasol Ewrop, £110,000
Smartexpertise - Technoleg Ysgythru Lled-ddargludyddion Penodol (ASSET) 2019 - 2022

Llywodraeth Cymru a Chronfa Datblygu Rhanbarthol Ewrop, £556,511.98
Monitro dŵr gwastraff o bell a pharhaus ar gyfer goruchwylio pandemig COVID19 yng Nghymru 2020 - 2021

Llywodraeth Cymru, £79,169.54

Dr Sanjiv Sharma

Cyfeiriad ebost

Dolenni Ymchwil

Trosolwg

Meysydd Arbenigedd

Uchafbwyntiau Ymchwil

Holl Ymchwil

Development of Graphene Based Biosensors for Early Detection of Alzheimer's Disease (dyfarnwyd 2023)

Creation and Optimisation of Plasma Etch Processes for the Manufacture of Silicon Microstructures (dyfarnwyd 2023)

Microneedles for Theranostics (cyfredol)

Development of Microneedles for Diagnostics and Therapeutics (dyfarnwyd 2023)

Coated subdermal wearable patches for real time continuous monitoring (cyfredol)

The Development of Silicon Microneedles (cyfredol)

EG-385 Polymers: Properties and Design

EGA109 Chemistry for Engineers

EGDM03 Individual Research Design Project

EGM403 Implant Engineering 2

EGNM07 Principles of Nanomedicine

EGTM89 Polymers: Properties and Design

Continuous monitoring diagnostics with microneedle arrays

Microneedles for Interstitial Fluid Physiology

Development of a minimally invasive continuous lactate monitoring sensor for clinical and sports applications

Towards a fully scalable minimally invasive, continuous glucose monitoring sensor, Type 1 diabetes

Microneedle array-based platform for future theranostic applications

Minimally invasive, continuous glucose monitoring in human subjects

Dyfeisiau brechu clyfar ar gyfer heintiau COVID-19 2020 - 2021

Ysgoloriaethau PhD Sgiliau'r Economi Wybodaeth (KESS) (2) 2018 - 2021

Smartexpertise - Technoleg Ysgythru Lled-ddargludyddion Penodol (ASSET) 2019 - 2022

Monitro dŵr gwastraff o bell a pharhaus ar gyfer goruchwylio pandemig COVID19 yng Nghymru 2020 - 2021