Yr Athro Paul Dyson

Athro, Biomedical Sciences

+44 (0) 1792 295667

p.j.dyson@abertawe.ac.uk

Swyddfa Academaidd - 532
Pumed Llawr - Microbiology
Y Sefydliad Gwyddor Bywyd 1
Campws Singleton

Ar gael ar gyfer Goruchwyliaeth Ôl-raddedig

Dolenni Ymchwil

https://orcid.org/0000-0002-0558-2666

ResearchGate

ResearcherID

Scopus

Trosolwg

Athro Dyson yw'r Microbiolegydd moleciwlaidd sy'n arwain grŵp ymchwil sy'n canolbwyntio ar ymelwa ar facteria defnyddiol ar gyfer meddygaeth a biotechnoleg.

Graddiodd yr Athro Dyson gyda BSc o Brifysgol East Anglia, PhD o Brifysgol Glasgow a DSc o Brifysgol Abertawe. Roedd ei yrfa ymchwil yn cynnwys cyfnodau yng Nghanada, yr Almaen a Ffrainc.

Mae ei ymchwil wedi arwain at 4 patent sy'n ymdrin â meysydd fel bacteria pridd sy'n cynhyrchu gwrthfiotigau, gan ddefnyddio bacteria symbiotig i dawelu mynegiant genynnau mewn pryfed, a manteisio ar facteria sy'n targedu tiwmor er mwyn canfod canser yn gynnar a darparu therapi.

Meysydd Arbenigedd

Geneteg
Bacteria Streptomyces sy'n cynhyrchu gwrthfiotigau
Trin genynnau o facteria
Ymyrraeth RNA mewn fectorau pryfed clefyd
Bacteria sy'n targedu tiwmor
Dadansoddiad mynegiant genynnau
Trawsosodiadau mewn bacteria

Uchafbwyntiau Gyrfa

Diddordebau Addysgu

Mae'r Athro Dyson yn cyfrannu at y cynlluniau gradd Geneteg a Biocemeg. Mae'n dysgu ac yn cydlynu modiwl blwyddyn olaf ar Ddatblygu Anifeiliaid, ac yn cyfrannu at fodiwlau ar Ficrobioleg Foleciwlaidd, Geneteg Dynol a Biotechnoleg. Mae'n fentor academaidd ar gyfer myfyrwyr israddedig ac ôl-raddedig ac mae'n goruchwylio sawl prosiect ymchwil israddedig a meistr bob blwyddyn.

Ymchwil Prif Wobrau Cydweithrediadau

Cyhoeddiadau

Uchafbwyntiau Ymchwil

Quinn, G. & Dyson, P. (2024). Going to extremes: progress in exploring new environments for novel antibiotics. npj Antimicrobials and Resistance, 2(1)
https://doi.org/10.1038/s44259-024-00025-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65922
Williams, J., Higgins, A., Stott, K., Thomas, C., Farrell, L., Bonnet, C., Peneva, S., Powell, A., Hay, T., Wang, T., Morgan, C., Dwyer, S., D’Ambrogio, J., Hogan, C., Smalley, M., Parry, L., & Dyson, P. (2024). Enhanced bacterial cancer therapy delivering therapeutic RNA interference of c-Myc. Cell and Bioscience, 14(1)
https://doi.org/10.1186/s13578-024-01206-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65889
Walker, M., Xue, Q., Taning, C., James, R., Smagghe, G., Sol, R., Hitchings, M., & Dyson, P. (2023). A narrow host-range and lack of persistence in two non-target insect species of a bacterial symbiont exploited to deliver insecticidal RNAi in Western Flower Thrips. Frontiers in Insect Science, 3
https://doi.org/10.3389/finsc.2023.1093970, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62479
http://dx.doi.org/10.3389/finsc.2023.1093970
Facey, P., Sevcikova, B., Novakova, R., Hitchings, M., Crack, J., Kormanec, J., Dyson, P., & Del Sol Abascal, R. (2011). Correction: The dpsA Gene of Streptomyces coelicolor: Induction of Expression from a Single Promoter in Response to Environmental Stress or during Development. PLoS ONE, 6(11)
https://doi.org/10.1371/annotation/8fedd9bb-d84e-4d7b-bc71-3321e652198d, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63747
http://dx.doi.org/10.1371/annotation/8fedd9bb-d84e-4d7b-bc71-3321e652198d
Ratcliffe, N., Mello, C., Castro, H., Dyson, P., & Barbosa Figueiredo Santangelo, M. (2024). Immune Reactions of Vector Insects to Parasites and Pathogens. Microorganisms, 12(3), 568
https://doi.org/10.3390/microorganisms12030568, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65880
Ratcliffe, N., Castro, H., Gonzalez, M., Mello, C., & Dyson, P. (2022). Reaching the Final Endgame for Constant Waves of COVID-19. Viruses, 14(12), 2637
https://doi.org/10.3390/v14122637, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62082
Sun, H., Tai, X., Chen, Y., Gao, T., Zhang, W., Liu, G., Chen, X., & Dyson, P. (2022). Efficient degradation of hydroquinone by a metabolically engineered Pseudarthrobacter sulfonivorans strain. Archives of Microbiology, 204(9)
https://doi.org/10.1007/s00203-022-03214-z, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa61748
Dyson, P., Walker, M., Andongma, A., & Barbosa Figueiredo Santangelo, M. (2021). Symbiont-Mediated RNA Interference (SMR): Using Symbiotic Bacteria as Vectors for Delivering RNAi to Insects.
https://doi.org/10.1007/978-1-0716-1633-8_21, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60220
Ratcliffe, N., Pacheco, J., Dyson, P., Castro, H., Gonzalez, M., Azambuja, P., & Mello, C. (2022). Overview of paratransgenesis as a strategy to control pathogen transmission by insect vectors. Parasites & Vectors, 15(1)
https://doi.org/10.1186/s13071-021-05132-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59749
Andongma, A., WHITTEN, M., Del Sol Abascal, R., Hitchings, M., & Dyson, P. (2022). Bacterial Competition Influences the Ability of Symbiotic Bacteria to Colonize Western Flower Thrips. Frontiers in Microbiology, 13
https://doi.org/10.3389/fmicb.2022.883891, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60193
http://dx.doi.org/10.3389/fmicb.2022.883891
Chen, X., Li, S., Zhang, B., Sun, H., Wang, J., Zhang, W., Meng, W., Chen, T., Dyson, P., & Liu, G. (2022). A new bacterial tRNA enhances antibiotic production in Streptomyces by circumventing inefficient wobble base-pairing. Nucleic Acids Research, 50(12), 7084-7096.
https://doi.org/10.1093/nar/gkac502, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60219
Vieira, C., Figueiredo, M., Moraes, C., Pereira, S., Dyson, P., Mello, C., Castro, D., & Azambuja, P. (2021). Azadirachtin interferes with basal immunity and microbial homeostasis in the Rhodnius prolixus midgut. Developmental & Comparative Immunology, 114, 103864
https://doi.org/10.1016/j.dci.2020.103864, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55174
Quinn, G., Abdelhameed, A., Banat, A., Alharbi, N., Baker, L., Castro, H., Dyson, P., Facey, P., Cobice, D., Terra, L., Adu, S., Swain, M., & Banat, I. (2021). Streptomyces Isolates from the Soil of an Ancient Irish Cure Site, Capable of Inhibiting Multi-Resistant Bacteria and Yeasts. Applied Sciences, 11(11), 4923
https://doi.org/10.3390/app11114923, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56959
Coombes, J., Gammon, J., Dyson, P., & Nigam, Y. (2021). Systematic review of hand rub active ingredients
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa58003
https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=247864
Araújo, C., Pacheco, J., Waniek, P., Geraldo, R., Sibajev, A., Santos, A., Evangelho, V., Dyson, P., Azambuja, P., Ratcliffe, N., Castro, H., & Mello, C. (2021). A rhamnose-binding lectin from Rhodnius prolixus and the impact of its silencing on gut bacterial microbiota and Trypanosoma cruzi. Developmental & Comparative Immunology, 114, 103823
https://doi.org/10.1016/j.dci.2020.103823, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55004
http://dx.doi.org/10.1016/j.dci.2020.103823
Andongma, A., Greig, C., Dyson, P., Flynn, N., & Walker, M. (2020). Optimization of dietary RNA interference delivery to western flower thrips Frankliniella occidentalis and onion thrips Thrips tabaci. Archives of Insect Biochemistry and Physiology, 103(3)
https://doi.org/10.1002/arch.21645, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52659
Zhang, B., Chen, T., Guo, J., Wu, M., Yang, R., Chen, X., Wu, X., Zhang, W., Kang, S., Liu, G., & Dyson, P. (2020). Microbial mercury methylation profile in terminus of a high-elevation glacier on the northern boundary of the Tibetan Plateau. Science of The Total Environment, 708, 135226
https://doi.org/10.1016/j.scitotenv.2019.135226, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52945
Terra, L., Dyson, P., Ratcliffe, N., Castro, H., & Vicente, A. (2020). Biotechnological Potential of Streptomyces Siderophores as New Antibiotics. Current Medicinal Chemistry, 27
https://doi.org/10.2174/0929867327666200510235512, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54197
Sol, R., Armstrong, I., Wright, C., Dyson, P., Dyson, P., Wright, C., & Del Sol Abascal, R. (2006). Characterization of Changes to the Cell Surface during the Life Cycle of Streptomyces coelicolor: Atomic Force Microscopy of Living Cells. Journal of Bacteriology, 189(6), 2219-2225.
https://doi.org/10.1128/JB.01470-06, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1416
Sol, R., Mullins, J., Grantcharova, N., Flardh, K., Dyson, P., Dyson, P., Del Sol Abascal, R., & Mullins, J. (2006). Influence of CrgA on Assembly of the Cell Division Protein FtsZ during Development of Streptomyces coelicolor. Journal of Bacteriology, 188(4), 1540
https://doi.org/10.1128/JB.188.4.1540-1550.2006, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1418
Eddy, F., Powell, A., Gregory, S., Nunan, L., Lightner, D., Dyson, P., Rowley, A., Shields, R., Rowley, A., Dyson, P., & Powell, A. (2007). A novel bacterial disease of the European shore crab, Carcinus maenas molecular pathology and epidemiology. Microbiology, 153(9), 2839
https://doi.org/10.1099/mic.0.2007/008391-0, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1467
Lamb, D., Lei, L., Zhao, B., Yuan, H., Jackson, C., Warrilow, A., Skaug, T., Dyson, P., Dawson, E., Kelly, S., Hachey, D., & Waterman, M. (2010). Streptomyces coelicolor A3(2) CYP102 Protein, a Novel Fatty Acid Hydroxylase Encoded as a Heme Domain without an N-Terminal Redox Partner. Applied and Environmental Microbiology, 76(6), 1975-1980.
https://doi.org/10.1128/AEM.03000-09, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa6357
Jones, G., Sol, R., Dudley, E., Dyson, P., & Del Sol Abascal, R. (2011). Forkhead-associated proteins genetically linked to the serine/threonine kinase PknB regulate carbon flux towards antibiotic biosynthesis in Streptomyces coelicolor. Microbial Biotechnology, 4(2), 263
https://doi.org/10.1111/j.1751-7915.2010.00237.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa9836
Facey, P., Hitchings, M., Saavedra-Garcia, P., Fernandez-Martinez, L., Dyson, P., Abascal, R., Dyson, P., Del Sol Abascal, R., Hitchings, M., & Facey, P. (2009). Streptomyces coelicolor Dps-like proteins: Differential dual roles in response to stress during vegetative growth and in nucleoid condensation during reproductive cell division. Molecular Microbiology, 73(6), 1186-202.
https://doi.org/10.1111/j.1365-2958.2009.06848.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa9837
Mistry, B., Sol, R., Wright, C., Findlay, K., Dyson, P., Dyson, P., Wright, C., & Del Sol Abascal, R. (2008). FtsW Is a Dispensable Cell Division Protein Required for Z-Ring Stabilization during Sporulation Septation in Streptomyces coelicolor. Journal of Bacteriology, 190(16), 5555-5566.
https://doi.org/10.1128/JB.00398-08, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa9839
Shah, F., Greig, C., Hutwimmer, S., Strasser, H., Dyson, P., Carlile, B., & Butt, T. (2010). Evaluation of the effects of the insect pathogenic fungus Metarhizium anisopliae on microbial populations of disparate plant growing media. Fungal Ecology, 3(3), 185-194.
https://doi.org/10.1016/j.funeco.2009.08.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa910
Akpe San Roman, S., Facey, P., Fernandez-Martinez, L., Rodriguez, C., Vallin, C., Del Sol, R., Dyson, P., Dyson, P., Del Sol Abascal, R., & Facey, P. (2010). A heterodimer of EsxA and EsxB is involved in sporulation and is secreted by a type VII secretion system in Streptomyces coelicolor. Microbiology, 156(6), 1719-1729.
https://doi.org/10.1099/mic.0.037069-0, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10232
Hitchings, M., Facey, P., Sevikova, B., Novakova, R., Hitchings, M., Crack, J., Kormanec, J., Dyson, P., Abascal, R., Dyson, P., Del Sol Abascal, R., & Facey, P. (2011). The dpsA Gene of Streptomyces coelicolor: Induction of Expression from a Single Promoter in Response to Environmental Stress or during. PlosOne, 6(9), e25593
https://doi.org/10.1371/journal.pone.0025593, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10243
Corradi, N., Liman, R., Facey, P., Keulen, G., Dyson, P., Sol, R., Del Sol Abascal, R., & Van Keulen, G. (2013). A Laterally Acquired Galactose Oxidase-Like Gene Is Required for Aerial Development during Osmotic Stress in Streptomyces coelicolor. PLoS ONE, 8(1), e54112
https://doi.org/10.1371/journal.pone.0054112, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13761
Pachebat, J., Keulen, G., Whitten, M., Girdwood, S., Sol, R., Dyson, P., Facey, P., Dyson, P., Walker, M., Del Sol Abascal, R., Van Keulen, G., & Facey, P. (2013). Draft Genome Sequence of Rhodococcus rhodnii Strain LMG5362, a Symbiont of Rhodnius prolixus (Hemiptera, Reduviidae, Triatominae), the Principle Vector of Trypanosoma cruzi. Genome Announcements, 1(3), e00329-13-e00329-13.
https://doi.org/10.1128/genomeA.00329-13, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa14827
Del Sol , R., Jones, H., Dyson, P., Del Sol Abascal, R., Hitchings, M., & Facey, P. (2014). A tale of tails: deciphering the contribution of terminal tails to the biochemical properties of two Dps proteins from Streptomyces coelicolor.. Cell Mol Life Sci
https://doi.org/10.1007/s00018-014-1658-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa18070
Sun, H., Gao, T., Chen, X., Hitchings, M., Li, S., Chen, T., Zhang, H., An, L., & Dyson, P. (2016). Complete genome sequence of a psychotrophic Arthrobacter strain A3 (CGMCC 1.8987), a novel long-chain hydrocarbons producer. Journal of Biotechnology, 222, 23-24.
https://doi.org/10.1016/j.jbiotec.2016.02.010, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26369
Del Sol Abascal, R., Dyson, P., Walker, M., Hitchings, M., Facey, P., & Meric, G. (2015). Draft genomes, phylogenetic reconstruction and comparative genomics of two novel cohabiting bacterial symbionts isolated from Frankliniella occidentalis.. Genome Biology and Evolution
https://doi.org/10.1093/gbe/evv136, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa22772
http://gbe.oxfordjournals.org/content/early/2015/07/15/gbe.evv136.long
Mejia, A., Millan-Pacheco, C., Barrios-Gonzalez, J., Sol, R., Dyson, P., Godinez, O., & Del Sol Abascal, R. (2015). Targeting the Osmotic Stress Response for Strain Improvement of an Industrial Producer of Secondary Metabolites. Journal of Microbiology and Biotechnology, 25(11), 1787-1795.
https://doi.org/10.4014/jmb.1503.03042, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa22773
http://www.jmb.or.kr/journal/viewJournal.html?doi=10.4014/jmb.1503.03042
Whitten, M., Dyson, P., & Walker, M. (2017). Gene silencing in non-model insects: Overcoming hurdles using symbiotic bacteria for trauma-free sustainable delivery of RNA interference. BioEssays, 39(3), 1600247
https://doi.org/10.1002/bies.201600247, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa32367
Chen, X., Hitchings, M., Mendoza, J., Balanza, V., Facey, P., Dyson, P., Bielza, P., Sol, R., & Del Sol Abascal, R. (2017). Comparative Genomics of Facultative Bacterial Symbionts Isolated from European Orius Species Reveals an Ancestral Symbiotic Association. Frontiers in Microbiology, 8
https://doi.org/10.3389/fmicb.2017.01969, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa35991
Zhang, B., Tang, S., Chen, X., Zhang, G., Zhang, W., Chen, T., Liu, G., Li, S., Dos Santos, L., Castro, H., Facey, P., Hitchings, M., & Dyson, P. (2018). Streptomyces qaidamensis sp. nov., isolated from sand in the Qaidam Basin, China. The Journal of Antibiotics
https://doi.org/10.1038/s41429-018-0080-9, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa41085
Terra, L., Dyson, P., Hitchings, M., Thomas, L., Abdelhameed, A., Banat, I., Gazze, S., Vujaklija, D., Facey, P., Francis, L., Quinn, G., & Dyson, P. (2018). A Novel Alkaliphilic Streptomyces Inhibits ESKAPE Pathogens. Frontiers in Microbiology, 9
https://doi.org/10.3389/fmicb.2018.02458, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa44961
http://dx.doi.org/10.3389/fmicb.2018.02458
Zhang, B., Wu, X., Tai, X., Sun, L., Wu, M., Zhang, W., Chen, X., Zhang, G., Chen, T., Liu, G., & Dyson, P. (2019). Variation in Actinobacterial Community Composition and Potential Function in Different Soil Ecosystems Belonging to the Arid Heihe River Basin of Northwest China. Frontiers in Microbiology, 10
https://doi.org/10.3389/fmicb.2019.02209, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52174
Zhang, B., Tang, S., Yang, R., Chen, X., Zhang, D., Zhang, W., Li, S., Chen, T., Liu, G., & Dyson, P. (2019). Streptomyces dangxiongensis sp. nov., isolated from soil of Qinghai-Tibet Plateau. International Journal of Systematic and Evolutionary Microbiology
https://doi.org/10.1099/ijsem.0.003550, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa50961
Ansari, M., Walker, M., Dyson, P., & Walker, M. (2019). Fungi as Biocontrol Agents of Culicoides Biting Midges, the Putative Vectors of Bluetongue Disease. Vector-Borne and Zoonotic Diseases
https://doi.org/10.1089/vbz.2018.2300, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa49699
Sherratt, D., Arthur, A., & Dyson, P. (1981). Site-specific recombination. Nature, 294(5842), 608-610.
https://doi.org/10.1038/294608a0, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45444
Dyson, P. (1983). Transposon-encoded site-specific recombination: nature of the Tn3 DNA sequences which constitute the recombination site res..
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45442
Dyson, P. (1984). Site-specific recombination in transposition and plasmid stability.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45441
Dyson, P. (1987). Relationship of an unstable argG gene to a 5.7-kilobase amplifiable DNA sequence in Streptomyces lividans 66.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45440
Dyson, P. (1987). Genetic instability and DNA amplification in Streptomyces lividans 66.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45439
Ray, T. & Dyson, P. (1992). Tris-dependent site-specific cleavage of Streptomyces lividans DNA. FEMS Microbiology Letters, 96(2-3), 247-252.
https://doi.org/10.1016/0378-1097(92)90412-H, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45438
Dyson, P. (1993). Pulsed-field gel electrophoresis of Streptomyces lividans DNA.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45437
Dyson, P. (1994). Characterization of a Streptomyces-lividans-type site-specific DNA modification system in the avermectin-producer Streptomyces avermitilis permits investigation of two novel giant linear plasmids, pSA1 and pSA2.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45436
Ray, T., Mills, A., & Dyson, P. (1995). Tris-dependent oxidative DNA strand scission during electrophoresis. Electrophoresis, 16(1), 888-894.
https://doi.org/10.1002/elps.11501601149, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45435

Holl Ymchwil

Erthyglau Cylchgronau

Quinn, G. & Dyson, P. (2024). Going to extremes: progress in exploring new environments for novel antibiotics. npj Antimicrobials and Resistance, 2(1)
https://doi.org/10.1038/s44259-024-00025-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65922
Williams, J., Higgins, A., Stott, K., Thomas, C., Farrell, L., Bonnet, C., Peneva, S., Powell, A., Hay, T., Wang, T., Morgan, C., Dwyer, S., D’Ambrogio, J., Hogan, C., Smalley, M., Parry, L., & Dyson, P. (2024). Enhanced bacterial cancer therapy delivering therapeutic RNA interference of c-Myc. Cell and Bioscience, 14(1)
https://doi.org/10.1186/s13578-024-01206-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65889
Ratcliffe, N., Mello, C., Castro, H., Dyson, P., & Barbosa Figueiredo Santangelo, M. (2024). Immune Reactions of Vector Insects to Parasites and Pathogens. Microorganisms, 12(3), 568
https://doi.org/10.3390/microorganisms12030568, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65880
Walker, M., Xue, Q., Taning, C., James, R., Smagghe, G., Sol, R., Hitchings, M., & Dyson, P. (2023). A narrow host-range and lack of persistence in two non-target insect species of a bacterial symbiont exploited to deliver insecticidal RNAi in Western Flower Thrips. Frontiers in Insect Science, 3
https://doi.org/10.3389/finsc.2023.1093970, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62479
http://dx.doi.org/10.3389/finsc.2023.1093970
Ratcliffe, N., Castro, H., Gonzalez, M., Mello, C., & Dyson, P. (2022). Reaching the Final Endgame for Constant Waves of COVID-19. Viruses, 14(12), 2637
https://doi.org/10.3390/v14122637, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62082
Sun, H., Tai, X., Chen, Y., Gao, T., Zhang, W., Liu, G., Chen, X., & Dyson, P. (2022). Efficient degradation of hydroquinone by a metabolically engineered Pseudarthrobacter sulfonivorans strain. Archives of Microbiology, 204(9)
https://doi.org/10.1007/s00203-022-03214-z, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa61748
Chen, X., Li, S., Zhang, B., Sun, H., Wang, J., Zhang, W., Meng, W., Chen, T., Dyson, P., & Liu, G. (2022). A new bacterial tRNA enhances antibiotic production in Streptomyces by circumventing inefficient wobble base-pairing. Nucleic Acids Research, 50(12), 7084-7096.
https://doi.org/10.1093/nar/gkac502, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60219
Andongma, A., WHITTEN, M., Del Sol Abascal, R., Hitchings, M., & Dyson, P. (2022). Bacterial Competition Influences the Ability of Symbiotic Bacteria to Colonize Western Flower Thrips. Frontiers in Microbiology, 13
https://doi.org/10.3389/fmicb.2022.883891, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60193
http://dx.doi.org/10.3389/fmicb.2022.883891
Ratcliffe, N., Pacheco, J., Dyson, P., Castro, H., Gonzalez, M., Azambuja, P., & Mello, C. (2022). Overview of paratransgenesis as a strategy to control pathogen transmission by insect vectors. Parasites & Vectors, 15(1)
https://doi.org/10.1186/s13071-021-05132-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59749
Quinn, G., Abdelhameed, A., Banat, A., Alharbi, N., Baker, L., Castro, H., Dyson, P., Facey, P., Cobice, D., Terra, L., Adu, S., Swain, M., & Banat, I. (2021). Streptomyces Isolates from the Soil of an Ancient Irish Cure Site, Capable of Inhibiting Multi-Resistant Bacteria and Yeasts. Applied Sciences, 11(11), 4923
https://doi.org/10.3390/app11114923, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56959
Vieira, C., Figueiredo, M., Moraes, C., Pereira, S., Dyson, P., Mello, C., Castro, D., & Azambuja, P. (2021). Azadirachtin interferes with basal immunity and microbial homeostasis in the Rhodnius prolixus midgut. Developmental & Comparative Immunology, 114, 103864
https://doi.org/10.1016/j.dci.2020.103864, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55174
Araújo, C., Pacheco, J., Waniek, P., Geraldo, R., Sibajev, A., Santos, A., Evangelho, V., Dyson, P., Azambuja, P., Ratcliffe, N., Castro, H., & Mello, C. (2021). A rhamnose-binding lectin from Rhodnius prolixus and the impact of its silencing on gut bacterial microbiota and Trypanosoma cruzi. Developmental & Comparative Immunology, 114, 103823
https://doi.org/10.1016/j.dci.2020.103823, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55004
http://dx.doi.org/10.1016/j.dci.2020.103823
Terra, L., Dyson, P., Ratcliffe, N., Castro, H., & Vicente, A. (2020). Biotechnological Potential of Streptomyces Siderophores as New Antibiotics. Current Medicinal Chemistry, 27
https://doi.org/10.2174/0929867327666200510235512, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54197
Zhang, B., Chen, T., Guo, J., Wu, M., Yang, R., Chen, X., Wu, X., Zhang, W., Kang, S., Liu, G., & Dyson, P. (2020). Microbial mercury methylation profile in terminus of a high-elevation glacier on the northern boundary of the Tibetan Plateau. Science of The Total Environment, 708, 135226
https://doi.org/10.1016/j.scitotenv.2019.135226, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52945
Andongma, A., Greig, C., Dyson, P., Flynn, N., & Walker, M. (2020). Optimization of dietary RNA interference delivery to western flower thrips Frankliniella occidentalis and onion thrips Thrips tabaci. Archives of Insect Biochemistry and Physiology, 103(3)
https://doi.org/10.1002/arch.21645, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52659
Ansari, M., Walker, M., Dyson, P., & Walker, M. (2019). Fungi as Biocontrol Agents of Culicoides Biting Midges, the Putative Vectors of Bluetongue Disease. Vector-Borne and Zoonotic Diseases
https://doi.org/10.1089/vbz.2018.2300, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa49699
Zhang, B., Tang, S., Yang, R., Chen, X., Zhang, D., Zhang, W., Li, S., Chen, T., Liu, G., & Dyson, P. (2019). Streptomyces dangxiongensis sp. nov., isolated from soil of Qinghai-Tibet Plateau. International Journal of Systematic and Evolutionary Microbiology
https://doi.org/10.1099/ijsem.0.003550, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa50961
Zhang, B., Wu, X., Tai, X., Sun, L., Wu, M., Zhang, W., Chen, X., Zhang, G., Chen, T., Liu, G., & Dyson, P. (2019). Variation in Actinobacterial Community Composition and Potential Function in Different Soil Ecosystems Belonging to the Arid Heihe River Basin of Northwest China. Frontiers in Microbiology, 10
https://doi.org/10.3389/fmicb.2019.02209, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52174
Terra, L., Dyson, P., Hitchings, M., Thomas, L., Abdelhameed, A., Banat, I., Gazze, S., Vujaklija, D., Facey, P., Francis, L., Quinn, G., & Dyson, P. (2018). A Novel Alkaliphilic Streptomyces Inhibits ESKAPE Pathogens. Frontiers in Microbiology, 9
https://doi.org/10.3389/fmicb.2018.02458, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa44961
http://dx.doi.org/10.3389/fmicb.2018.02458
Zhang, B., Tang, S., Chen, X., Zhang, G., Zhang, W., Chen, T., Liu, G., Li, S., Dos Santos, L., Castro, H., Facey, P., Hitchings, M., & Dyson, P. (2018). Streptomyces qaidamensis sp. nov., isolated from sand in the Qaidam Basin, China. The Journal of Antibiotics
https://doi.org/10.1038/s41429-018-0080-9, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa41085
Dyson, P. (2018). Using microbes for precision insect pest control. Microbiology Today
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45416
https://microbiologysociety.org/publication/past-issues/modern-microbes-microbial-tools/article/using-microbes-for-precision-insect-pest-control.html
Chen, X., Li, J., Sun, H., Li, S., Chen, T., Liu, G., & Dyson, P. (2017). High-level heterologous production and Functional Secretion by recombinant Pichia pastoris of the shortest proline-rich antibacterial honeybee peptide Apidaecin. Scientific Reports, 7(1)
https://doi.org/10.1038/s41598-017-15149-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36658
Chen, X., An, L., Fan, X., Ju, F., Zhang, B., Sun, H., Xiao, J., Hu, W., Qu, T., Guan, L., Tang, S., Chen, T., Liu, G., & Dyson, P. (2017). A trehalose biosynthetic enzyme doubles as an osmotic stress sensor to regulate bacterial morphogenesis. PLOS Genetics, 13(10), e1007062
https://doi.org/10.1371/journal.pgen.1007062, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36636
Chen, X., Hitchings, M., Mendoza, J., Balanza, V., Facey, P., Dyson, P., Bielza, P., Sol, R., & Del Sol Abascal, R. (2017). Comparative Genomics of Facultative Bacterial Symbionts Isolated from European Orius Species Reveals an Ancestral Symbiotic Association. Frontiers in Microbiology, 8
https://doi.org/10.3389/fmicb.2017.01969, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa35991
Whitten, M., Dyson, P., & Walker, M. (2017). Gene silencing in non-model insects: Overcoming hurdles using symbiotic bacteria for trauma-free sustainable delivery of RNA interference. BioEssays, 39(3), 1600247
https://doi.org/10.1002/bies.201600247, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa32367
Zhang, B., Dyson, P., Zhang, W., Tang, S., Zhang, L., Liu, G., Zhang, G., Chen, X., Chen, T., & Li, S. (2016). Streptomyces lacrimifluminis sp. nov., a novel actinobacterium that produces antibacterial compounds isolated from soil from the Qinghai-Tibet Plateau. International Journal of Systematic and Evolutionary Microbiology
https://doi.org/10.1099/ijsem.0.001456, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30357
Fuchino, K., Flärdh, K., Dyson, P., & Ausmees, N. (2016). Cell-biological studies of osmotic shock response in Streptomyces spp.. Journal of Bacteriology, 199(1), JB.00465-16
https://doi.org/10.1128/JB.00465-16, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa31099
Zhang, H., Sun, H., Yang, R., Li, S., Zhou, M., Gao, T., An, L., Chen, X., & Dyson, P. (2016). Complete genome sequence of a psychotrophic Pseudarthrobacter sulfonivorans strain Ar51 (CGMCC 4.7316), a novel crude oil and multi benzene compounds degradation strain. Journal of Biotechnology, 231, 81-82.
https://doi.org/10.1016/j.jbiotec.2016.04.010, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa29536
Sun, H., Gao, T., Chen, X., Hitchings, M., Li, S., Chen, T., Zhang, H., An, L., & Dyson, P. (2016). Complete genome sequence of a psychotrophic Arthrobacter strain A3 (CGMCC 1.8987), a novel long-chain hydrocarbons producer. Journal of Biotechnology, 222, 23-24.
https://doi.org/10.1016/j.jbiotec.2016.02.010, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26369
Facey, P., Fernández-Martínez, L., Evans, M., Mitchell, J., Bodger, O., Dyson, P., Walker, M., & Del Sol Abascal, R. (2016). Symbiont-mediated RNA interference in insects. Proceedings of the Royal Society B: Biological Sciences, 283(1825), 20160042
https://doi.org/10.1098/rspb.2016.0042, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26533
Zhang, B., Wu, X., Zhang, W., Chen, X., Zhang, G., Ai, X., Sun, L., Zhang, B., Liu, G., Chen, T., & Dyson, P. (2015). Diversity and succession of Actinobacteria in the forelands of the Tianshan Glacier, China. Geomicrobiology Journal, 00-00.
https://doi.org/10.1080/01490451.2015.1085468, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa24541
Chen, X., Zhang, B., Xiao, J., Ju, F., Li, S., Ren, C., An, L., Chen, T., Liu, G., Facey, P., Mullins, J., & Dyson, P. (2015). RfiA, a novel PAP2 domain-containing polytopic membrane protein that confers resistance to the FtsZ inhibitor PC190723. Future Microbiology, 10(3), 325-335.
https://doi.org/10.2217/fmb.14.131, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa20615
http://www.futuremedicine.com/doi/abs/10.2217/fmb.14.131?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dwww.ncbi.nlm.nih.gov
Kämpfer, P., Glaeser, S., Parkes, L., van Keulen, G., & Dyson, P. (2015). The Family Streptomycetaceae. The Prokaryotes-1010.
https://doi.org/10.1007/978-3-642-30138-4_184, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa20118
Del Sol Abascal, R., Dyson, P., Walker, M., Hitchings, M., Facey, P., & Meric, G. (2015). Draft genomes, phylogenetic reconstruction and comparative genomics of two novel cohabiting bacterial symbionts isolated from Frankliniella occidentalis.. Genome Biology and Evolution
https://doi.org/10.1093/gbe/evv136, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa22772
http://gbe.oxfordjournals.org/content/early/2015/07/15/gbe.evv136.long
Mejia, A., Millan-Pacheco, C., Barrios-Gonzalez, J., Sol, R., Dyson, P., Godinez, O., & Del Sol Abascal, R. (2015). Targeting the Osmotic Stress Response for Strain Improvement of an Industrial Producer of Secondary Metabolites. Journal of Microbiology and Biotechnology, 25(11), 1787-1795.
https://doi.org/10.4014/jmb.1503.03042, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa22773
http://www.jmb.or.kr/journal/viewJournal.html?doi=10.4014/jmb.1503.03042
Zhang, W., Wu, X., Liu, G., Dong, Z., Zhang, G., Chen, T., & Dyson, P. (2014). Tag-encoded pyrosequencing analysis of bacterial diversity within different alpine grassland ecosystems of the Qinghai-Tibet Plateau, China. Environmental Earth Sciences, 72(3), 779-786.
https://doi.org/10.1007/s12665-013-3001-z, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa20133
van Keulen, G. & Dyson, P. (2014). Production of Specialized Metabolites by Streptomyces coelicolor A3(2). Adv Appl Microbiol, 89, 217-266.
https://doi.org/10.1016/B978-0-12-800259-9.00006-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa18368
Del Sol , R., Jones, H., Dyson, P., Del Sol Abascal, R., Hitchings, M., & Facey, P. (2014). A tale of tails: deciphering the contribution of terminal tails to the biochemical properties of two Dps proteins from Streptomyces coelicolor.. Cell Mol Life Sci
https://doi.org/10.1007/s00018-014-1658-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa18070
Pachebat, J., Keulen, G., Whitten, M., Girdwood, S., Sol, R., Dyson, P., Facey, P., Dyson, P., Walker, M., Del Sol Abascal, R., Van Keulen, G., & Facey, P. (2013). Draft Genome Sequence of Rhodococcus rhodnii Strain LMG5362, a Symbiont of Rhodnius prolixus (Hemiptera, Reduviidae, Triatominae), the Principle Vector of Trypanosoma cruzi. Genome Announcements, 1(3), e00329-13-e00329-13.
https://doi.org/10.1128/genomeA.00329-13, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa14827
Chen, X., Zhang, B., Zhang, W., Wu, X., Zhang, M., Chen, T., Liu, G., Dyson, P., & Dyson, P. (2013). Genome Sequence of Streptomyces violaceusniger Strain SPC6, a Halotolerant Streptomycete That Exhibits Rapid Growth and Development. Genome Announcements, 1(4), e00494-13-e00494-13.
https://doi.org/10.1128/genomeA.00494-13, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa18370
Dyson, P., Del Sol Abascal, R., Francis, L., & Facey, P. (2013). A novel bifunctional histone protein in Streptomyces: a candidate for structural coupling between DNA conformation and transcription during development and stress?. Nucleic Acids Research
https://doi.org/10.1093/nar/gkt180, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa14456
Dale, C., Facey, P., Hitchings, M., Williams, J., Skibinski, D., Dyson, P., Sol, R., & Del Sol Abascal, R. (2013). The Evolution of an Osmotically Inducible dps in the Genus Streptomyces. PLoS ONE, 8(4)
https://doi.org/10.1371/journal.pone.0060772, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa14547
Corradi, N., Liman, R., Facey, P., Keulen, G., Dyson, P., Sol, R., Del Sol Abascal, R., & Van Keulen, G. (2013). A Laterally Acquired Galactose Oxidase-Like Gene Is Required for Aerial Development during Osmotic Stress in Streptomyces coelicolor. PLoS ONE, 8(1), e54112
https://doi.org/10.1371/journal.pone.0054112, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13761
Gregory, S., Dyson, P., Fletcher, D., Gatland, P., & Shields, R. (2012). Nitrogen removal and changes to microbial communities in model flood/drain and submerged biofilters treating aquaculture wastewater. Aquacultural Engineering
https://doi.org/10.1016/j.aquaeng.2012.03.006, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa11276
Zhang, W., Zhang, G., Liu, G., Dong, Z., Chen, T., Zhang, M., Dyson, P., & Lizhe, A. (2012). Bacterial diversity and distribution in the southeast edge of the Tengger Desert and their correlation with soil enzyme activities. Journal of Environmental Sciences, 24(11), 2004-2011.
https://doi.org/10.1016/S1001-0742(11)61037-1, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13887
Chen, X., Jiang, Y., Li, Y., Zhang, H., Li, J., Chen, X., Zhao, Q., Zhao, J., Si, J., Lin, Z., Zhang, H., Dyson, P., & An, L. (2011). Regulation of expression of trehalose-6-phosphate synthase during cold shock in Arthrobacter strain A3. Extremophiles, 15(4), 499-508.
https://doi.org/10.1007/s00792-011-0380-5, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45418
Cheng, X., Jiang, Y., Li, Y., & Dyson, P. (2011). Regulation of expression of trehalose-6-phosphate synthase during cold shock in Arthrobacter strain A3.. Extremophiles, 15, 499-508.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10164
Jones, G., Sol, R., Dudley, E., & Dyson, P. (2011). Forkhead-associated proteins genetically linked to the serine/threonine kinase PknB regulate carbon flux towards antibiotic biosynthesis in Streptomyces coelicolor.. Microbial Biotechnology, 4, 263-74.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10223
Fernandez-Martinez, L., Sol, R., Evans, M., Dyson, P., & Del Sol Abascal, R. (2011). A transposon insertion single-gene knockout library and new ordered cosmid library for the model organism Streptomyces coelicolor A3(2). Antonie Van Leeuwenhoek, 99, 515-22.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10224
Hitchings, M., Facey, P., Sevikova, B., Novakova, R., Hitchings, M., Crack, J., Kormanec, J., Dyson, P., Abascal, R., Dyson, P., Del Sol Abascal, R., & Facey, P. (2011). The dpsA Gene of Streptomyces coelicolor: Induction of Expression from a Single Promoter in Response to Environmental Stress or during. PlosOne, 6(9), e25593
https://doi.org/10.1371/journal.pone.0025593, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10243
Jones, G., Sol, R., Dudley, E., Dyson, P., & Del Sol Abascal, R. (2011). Forkhead-associated proteins genetically linked to the serine/threonine kinase PknB regulate carbon flux towards antibiotic biosynthesis in Streptomyces coelicolor. Microbial Biotechnology, 4(2), 263
https://doi.org/10.1111/j.1751-7915.2010.00237.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa9836
Facey, P., Sevcikova, B., Novakova, R., Hitchings, M., Crack, J., Kormanec, J., Dyson, P., & Del Sol Abascal, R. (2011). Correction: The dpsA Gene of Streptomyces coelicolor: Induction of Expression from a Single Promoter in Response to Environmental Stress or during Development. PLoS ONE, 6(11)
https://doi.org/10.1371/annotation/8fedd9bb-d84e-4d7b-bc71-3321e652198d, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63747
http://dx.doi.org/10.1371/annotation/8fedd9bb-d84e-4d7b-bc71-3321e652198d
Lamb, D., Lei, L., Zhao, B., Yuan, H., Jackson, C., Warrilow, A., Skaug, T., Dyson, P., Dawson, E., Kelly, S., Hachey, D., & Waterman, M. (2010). Streptomyces coelicolor A3(2) CYP102 Protein, a Novel Fatty Acid Hydroxylase Encoded as a Heme Domain without an N-Terminal Redox Partner. Applied and Environmental Microbiology, 76(6), 1975-1980.
https://doi.org/10.1128/AEM.03000-09, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa6357
Shah, F., Greig, C., Hutwimmer, S., Strasser, H., Dyson, P., Carlile, B., & Butt, T. (2010). Evaluation of the effects of the insect pathogenic fungus Metarhizium anisopliae on microbial populations of disparate plant growing media. Fungal Ecology, 3(3), 185-194.
https://doi.org/10.1016/j.funeco.2009.08.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa910
Gregory, S., Shields, R., Fletcher, D., & Dyson, P. (2010). Bacterial community responses to increasing ammonia concentrations in model recirculating vertical flow saline biofilters. Ecol Eng, 36, 1485-1491.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10225
Jiang, Y., Chen, X., Liu, Y., Yuan-Ting, L., Zhang, H., Dyson, P., Sheng, H., & Li-Zhe, A. (2010). The catalytic efficiency of trehalose-6-phosphate synthase is effected by the N-loop at low temperatures. Archives of Microbiology, 192(11), 937-943.
https://doi.org/10.1007/s00203-010-0625-1, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa11668
Akpe San Roman, S., Facey, P., Fernandez-Martinez, L., Rodriguez, C., Vallin, C., Del Sol, R., Dyson, P., Dyson, P., Del Sol Abascal, R., & Facey, P. (2010). A heterodimer of EsxA and EsxB is involved in sporulation and is secreted by a type VII secretion system in Streptomyces coelicolor. Microbiology, 156(6), 1719-1729.
https://doi.org/10.1099/mic.0.037069-0, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10232
Facey, P., Hitchings, M., Saavedra-Garcia, P., & Dyson, P. (2009). Streptomyces coelicolor Dps-like proteins: Differential dual roles in response to stress during vegetative growth and in nucleoid condensation during reproductive cell division. Molecular Microbiology, 73, 1186-1202.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa9858
Martínez, L., Bishop, A., Parkes, L., Sol, R., Salerno, P., Sevcikova, B., Mazurakova, V., Kormanec, J., Dyson, P., & Del Sol Abascal, R. (2009). Osmoregulation inStreptomyces coelicolor: modulation of SigB activity by OsaC. Molecular Microbiology, 71(5), 1250-1262.
https://doi.org/10.1111/j.1365-2958.2009.06599.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa9859
Facey, P., Hitchings, M., Saavedra-Garcia, P., Fernandez-Martinez, L., Dyson, P., Abascal, R., Dyson, P., Del Sol Abascal, R., Hitchings, M., & Facey, P. (2009). Streptomyces coelicolor Dps-like proteins: Differential dual roles in response to stress during vegetative growth and in nucleoid condensation during reproductive cell division. Molecular Microbiology, 73(6), 1186-202.
https://doi.org/10.1111/j.1365-2958.2009.06848.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa9837
Mistry, B., Sol, R., Wright, C., & Dyson, P. (2008). FtsW is a dispensable cell division protein required for Z-ring stabilisation during sporulation septation in Streptomyces coelicolor.. Journal of Bacteriology, 190, 5555-5566.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa9856
Mistry, B., Sol, R., Wright, C., Findlay, K., Dyson, P., Dyson, P., Wright, C., & Del Sol Abascal, R. (2008). FtsW Is a Dispensable Cell Division Protein Required for Z-Ring Stabilization during Sporulation Septation in Streptomyces coelicolor. Journal of Bacteriology, 190(16), 5555-5566.
https://doi.org/10.1128/JB.00398-08, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa9839
Eddy, F., Powell, A., Gregory, S., Nunan, L., Lightner, D., Dyson, P., Rowley, A., Shields, R., Rowley, A., Dyson, P., & Powell, A. (2007). A novel bacterial disease of the European shore crab, Carcinus maenas molecular pathology and epidemiology. Microbiology, 153(9), 2839
https://doi.org/10.1099/mic.0.2007/008391-0, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1467
Dyson, P. (2007). Characterization of Changes to the Cell Surface during the Life Cycle of Streptomyces coelicolor: Atomic Force Microscopy of Living Cells. Journal of Bacteriology, 189(6)-2225.
https://doi.org/10.1128/JB.01470-06, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa14545
Jones, G., Dyson, P., & Dyson, P. (2006). Evolution of Transmembrane Protein Kinases Implicated in Coordinating Remodeling of Gram-Positive Peptidoglycan: Inside versus Outside. Journal of Bacteriology, 188(21), 7470-7476.
https://doi.org/10.1128/JB.00800-06, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1387
Sol, R., Armstrong, I., Wright, C., Dyson, P., Dyson, P., Wright, C., & Del Sol Abascal, R. (2006). Characterization of Changes to the Cell Surface during the Life Cycle of Streptomyces coelicolor: Atomic Force Microscopy of Living Cells. Journal of Bacteriology, 189(6), 2219-2225.
https://doi.org/10.1128/JB.01470-06, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1416
Sol, R., Mullins, J., Grantcharova, N., Flardh, K., Dyson, P., Dyson, P., Del Sol Abascal, R., & Mullins, J. (2006). Influence of CrgA on Assembly of the Cell Division Protein FtsZ during Development of Streptomyces coelicolor. Journal of Bacteriology, 188(4), 1540
https://doi.org/10.1128/JB.188.4.1540-1550.2006, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1418
Dyson, P. (2004). Transposon Express, a software application to report the identity of insertions obtained by comprehensive transposon mutagenesis of sequenced genomes: analysis of the preference for in vitro Tn5 transposition into GC-rich DNA..
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45423
Herron, P. & Dyson, P. (2004). Transposon Express, a software application to report the identity of insertions obtained by comprehensive transposon mutagenesis of sequenced genomes: analysis of the preference for in vitro Tn5 transposition into GC-rich DNA. Nucleic Acids Research, 32(14), e113-e113.
https://doi.org/10.1093/nar/gnh112, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1385
Bishop, A. & Dyson, P. (2004). Systematic Insertional Mutagenesis of a Streptomycete Genome: A Link Between Osmoadaptation and Antibiotic Production. Genome Research, 14(5), 893-900.
https://doi.org/10.1101/gr.1710304, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1386
Sol, R., Pitman, A., Herron, P., Dyson, P., Dyson, P., & Del Sol Abascal, R. (2003). The Product of a Developmental Gene, crgA, That Coordinates Reproductive Growth in Streptomyces Belongs to a Novel Family of Small Actinomycete-Specific Proteins. Journal of Bacteriology, 185(22), 6678-6685.
https://doi.org/10.1128/JB.185.22.6678-6685.2003, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1384
Dyson, P. (2002). Osmotic regulation of the Streptomyces lividans thiostrepton-inducible promoter, ptipA.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45425
Pitman, A., Herron, P., & Dyson, P. (2002). Cointegrate resolution following transposition of Tn1792 in Streptomyces avermitilis facilitates analysis of transposon-tagged genes. Journal of Microbiological Methods, 49(1), 89-96.
https://doi.org/10.1016/S0167-7012(01)00353-0, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45424
Herron, P. & Dyson, P. (1999). Low target site specificity of an IS6100-based mini-transposon, Tn1792, developed for transposon mutagenesis of antibiotic-producing Streptomyces. FEMS Microbiology Letters, 171(2), 215-221.
https://doi.org/10.1016/S0378-1097(98)00608-9, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45429
Dyson, P. (1999). Genetic instability associated with insertion of IS6100 into one end of the Streptomyces lividans chromosome.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45428
Dyson, P. (1998). Transposon mutagenesis with IS6100 in the avermectin-producer Streptomyces avermitilis.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45432
Boybek, A., Ray, T., Evans, M., Dyson, P., & Dyson, P. (1998). Novel site-specific DNA modification in Streptomyces: Analysis of preferred intragenic modification sites present in a 5.7 kb amplified DNA sequence. Nucleic Acids Research, 26(14), 3364-3371.
https://doi.org/10.1093/nar/26.14.3364, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45431
Dyson, P. & Dyson, P. (1998). Novel post-replicative DNA modification in Streptomyces: analysis of the preferred modification site of plasmid pIJ101. Nucleic Acids Research, 26(5), 1248-1253.
https://doi.org/10.1093/nar/26.5.1248, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45430
Dyson, P. & Evans, M. (1996). pUCS75, a stable high-copy-number Streptomyces—Escherichia coli shuttle vector which facilitates subcloning from pUC plasmid and M 13 phage vectors. Gene, 171(1), 71-73.
https://doi.org/10.1016/0378-1119(96)00064-9, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45433
Ray, T., Mills, A., & Dyson, P. (1995). Tris-dependent oxidative DNA strand scission during electrophoresis. Electrophoresis, 16(1), 888-894.
https://doi.org/10.1002/elps.11501601149, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45435
Dyson, P. (1995). Inducible transposition in Streptomyces lividans of insertion sequence IS6100 from Mycobacterium fortuitum.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45434
Dyson, P. (1994). Characterization of a Streptomyces-lividans-type site-specific DNA modification system in the avermectin-producer Streptomyces avermitilis permits investigation of two novel giant linear plasmids, pSA1 and pSA2.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45436
Dyson, P. (1993). Pulsed-field gel electrophoresis of Streptomyces lividans DNA.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45437
Ray, T. & Dyson, P. (1992). Tris-dependent site-specific cleavage of Streptomyces lividans DNA. FEMS Microbiology Letters, 96(2-3), 247-252.
https://doi.org/10.1016/0378-1097(92)90412-H, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45438
Dyson, P. (1987). Relationship of an unstable argG gene to a 5.7-kilobase amplifiable DNA sequence in Streptomyces lividans 66.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45440
Dyson, P. (1987). Genetic instability and DNA amplification in Streptomyces lividans 66.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45439
Dyson, P. (1984). Site-specific recombination in transposition and plasmid stability.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45441
Dyson, P. (1983). Transposon-encoded site-specific recombination: nature of the Tn3 DNA sequences which constitute the recombination site res..
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45442
Sherratt, D., Arthur, A., & Dyson, P. (1981). Site-specific recombination. Nature, 294(5842), 608-610.
https://doi.org/10.1038/294608a0, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45444

Llyfrau Awdurol

Dyson, P. (2002). Streptomyces coelicolor A3(2): from genome sequence to function
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45426
Dyson, P. (1999). Genetic Methods for Diverse Prokaryotes
https://doi.org/10.1016/S0580-9517(08)70115-6, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45427

Penodau Llyfrau

Dyson, P. (2014). Streptomyces. Reference Module in Biomedical Sciences Elsevier
https://doi.org/10.1016/B978-0-12-801238-3.02306-0, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa20130

Cynnyrch Ymchwil Arall

Dyson, P., Walker, M., Andongma, A., & Barbosa Figueiredo Santangelo, M. (2021). Symbiont-Mediated RNA Interference (SMR): Using Symbiotic Bacteria as Vectors for Delivering RNAi to Insects.
https://doi.org/10.1007/978-1-0716-1633-8_21, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60220
Coombes, J., Gammon, J., Dyson, P., & Nigam, Y. (2021). Systematic review of hand rub active ingredients
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa58003
https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=247864

Goruchwyliaeth

Enhancing translation efficiency to improve antibiotic production by streptomyces (cyfredol)

PhD

Goruchwyliwr arall: Dr Ricardo Del Sol Abascal
A comprehensive investigation of the clinical outcomes of alcohol free hand rubs. (cyfredol)

PhD

Goruchwyliwr arall: Prof Yamni Nigam

Goruchwyliwr arall: Prof John Gammon
Identification and Characterisation of The Immune Response to Salmonella-mediated Cancer Therapy and Its Use in Developing Combination Cancer Therapy (cyfredol)

PhD

Goruchwyliwr arall: Dr Nick Jones
Facultative bacterial symbionts from European Orius species: Evidence for an ancestral symbiotic association. (dyfarnwyd 2022)

PhD

Goruchwyliwr arall: Dr Ricardo Del Sol Abascal
Bacterial Targeting and Manipulation of Tumour Cell Metabolism (cyfredol)

PhD

Goruchwyliwr arall: Dr Claire Morgan

Modiwlau a Addysgir

PM-226 Human and Medical Genetics

The course is designed to introduce fundamental concepts in the study of human genetics with particular reference to the application of the principles to medicine. The course covers the role of genetics in human health and disease and methods for the detection of genetic variability in human populations.
PM-251 Microbial Molecular Genetics

The control systems governing gene expression in prokaryotic cells are explored and the molecular basis for gene regulation introduced. Practical skills in obtaining and analysing data on a bacterial system are developed. The module then assesses the structure of the bacterial genome and how genetic analysis can be used to investigate structure and function of individual components of that genome. Specific examples explored in depth are the genetics of recombination and DNA repair. The technologies used for functional genomic analysis of fully sequenced bacteria are described with reference to analysis of human pathogens. Finally, the module includes examples of synthetic biology applied to bacteria.
PM-280 Skills for Researchers

The modern scientist graduate is expected to have gained extensive laboratory-based experience and this is certainly essential for any student intent on pursuing a research-based career. Skills for Researchers provides students with the opportunity to acquire the core skills to be able to conduct, analyse, interpret and present scientific experiments. A proportion of the module will be spent in the laboratory gaining hands-on experience. Skills acquired in this module will form the basis for future experimental work, including the final year project. Students will have the opportunity to provide feedback to peers and engage with a variety of online learning materials.
PM-308 Animal Development

The module provides an understanding of the principles of animal development, introducing critical genes and their products that play roles in regulating metazoan development. Classical embryology will be integrated with contemporary molecular investigations into developmental mechanisms.
PM-344 Capstone Project

The aim of this module is to provide a capstone experience to students¿ learning, through participating in their own enquiry-based research project, with guidance from an academic supervisor. The project may be laboratory or non-laboratory based, but it will always involve a research question that is drawn from the literature, and focused on a topic relevant to the life sciences. It will ask a research question and involve the critical analysis of research findings. Students will refine their oral and written communication skills to a graduate level through an oral presentation and dissertation on their research findings and conclusions.
PM-400 Advanced Research Project A

The advanced research project is a key component of the final year of study, providing students with experience of conducting cutting-edge research in the Institute of Life Science and Centre for Nanohealth over an extended period of time. The project will fall into one of the current medically-related research themes: Biomarkers and Genes; Microbes and Immunity; Devices and health informatics. Students will employ a range of advanced analytical procedures to investigate a specific topic. In addition, they will gain experience in preparing a research proposal and presenting their data in various formats. Research topics will be assigned that are appropriate to a specific degree title. For example, a Genetics student could be assigned a project investigating gene function in an insect vector of a tropical disease, using the technique of RNA interference. The advanced research project is divided between 2 modules, PM-400 and PM-405.
PM-405 Advanced Research Project Dissertation

The advanced research project is a key component of the final year of study, providing students with experience of conducting cutting-edge research in the Institute of Life Science and Centre for Nanohealth over an extended period. The projects undertaken will fall into one of the current medically-related research themes. Students will employ a range of advanced analytical procedures to investigate a specific topic. In addition, they will gain experience in preparing a research proposal and presenting their data in various formats. Research topics will be assigned that are appropriate to a specific degree title.

Yr Athro Paul Dyson

Rhif ffôn

Cyfeiriad ebost

LinkedIn Account

Dolenni Ymchwil

Trosolwg

Meysydd Arbenigedd

Uchafbwyntiau Gyrfa

Cyhoeddiadau

Uchafbwyntiau Ymchwil

Holl Ymchwil

Erthyglau Cylchgronau

Llyfrau Awdurol

Penodau Llyfrau

Cynnyrch Ymchwil Arall

Goruchwyliaeth

Enhancing translation efficiency to improve antibiotic production by streptomyces (cyfredol)

A comprehensive investigation of the clinical outcomes of alcohol free hand rubs. (cyfredol)

Identification and Characterisation of The Immune Response to Salmonella-mediated Cancer Therapy and Its Use in Developing Combination Cancer Therapy (cyfredol)

Facultative bacterial symbionts from European Orius species: Evidence for an ancestral symbiotic association. (dyfarnwyd 2022)

Bacterial Targeting and Manipulation of Tumour Cell Metabolism (cyfredol)

Modiwlau a Addysgir

PM-226 Human and Medical Genetics

PM-251 Microbial Molecular Genetics

PM-280 Skills for Researchers

PM-308 Animal Development

PM-344 Capstone Project

PM-400 Advanced Research Project A

PM-405 Advanced Research Project Dissertation