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Introduction . topb(1).gif (622 bytes)
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Two very important positions on the committee will be available at the Swansea meeting next year – see below for details. Nominations for the UKEMS Young Scientist Award for 2000 are now closed, and we are delighted to have to consider two outstanding candidates. The judges will be making their deliberations in the next few weeks. Finally, please could all members ensure Kevin has their E-mail address, as there may come a time when we can contact all members by E-mail and save a great deal of paper and postage. Merry Christmas everyone.


Meetings . topb(1).gif (622 bytes)
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Included with this Newsletter is an outline programme for the Millennium meeting in Swansea. The "Careers in Genetic Toxicology Discussion Group for young scientists" on the Sunday evening provides an opportunity for students, post-docs and young technicians to hear more senior scientists from Pharmaceutical, CRO and academic backgrounds talking about career and job prospects available to young people in our field of interest. Drinks and snacks will be provided, but we hope you will come for the discussion, too.

At last months committee meeting, we discussed how important it is for students to get to the annual scientific meetings, and decided that registration for Swansea 2000 will be free to all students and young scientists who wish to attend. Furthermore, any applications from students for travel bursaries to this, to EEMS in Budapest, and to any other relevant meetings, will be considered seriously, particularly if the applicant is presenting a poster or paper at the meeting.

UKEMS Committee . topb(1).gif (622 bytes)
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As Michael ends his two years as president at the 2000 AGM, and Barry takes over this post, we will need to appoint a new Vice-President. This is a critical appointment since the candidate becomes the President after two years. We are also seeking a Treasurer-Elect, to work alongside Kevin from July of next year with a view to taking over as treasurer at the 2001 AGM. Again, this is an important post looking after all financial and membership aspects of the Society. A nomination form is attached and completed forms should be sent to me by the end of February 2000.


IGG News . topb(1).gif (622 bytes)

At the September IGG Committee meeting, Julie Clements was elected as Chairperson – thanks are due to the outgoing Peter Jenkinson for his contribution over the past few years. At the time of writing, the next IGG meeting at the Royal Society of Medicine on 6 December is fast approaching. The theme will be "Cytotoxicity in vitro", with emphasis on the mammalian cell assays. The day will begin with some general talks on mechanisms of cytotoxicity and then we will compare and contrast the measures of cytotoxicity used in various genotoxicity assays. A questionnaire has prompted an excellent response and several laboratories have data to present so this promises to be a lively session. Different approaches to measurement of cytotoxicity, and interpretation of data which are generated at highly cytotoxic concentrations, will be covered. Towards the end of the day there will be an opportunity to hear about new or alternative ways of measuring cytotoxicity.

Other issues to note: The May meeting on "Ethical use of animals in genotoxicity testing" has stimulated some interesting discussion. IGG members have also provided feedback on a variety of issues to COM (Committee on Mutagenicity, an Advisory committee of the UK Department of Health) who are currently revising their guidelines. At the UKEMS Committee meeting last month it was decided that a co-ordinated response will be prepared for the end of January 2000 and it is likely that working groups will need to be established to formulate new UKEMS guidelines on the in vitro micronucleus and COMET assays.

Finally, several key speakers from international regulatory authorities have agreed to speak at the session being organised by IGG on "Worldwide genotoxicology testing strategies", part of the UKEMS 2000 meeting in Swansea.

The IGG committee are always keen to hear your thoughts or ideas eg is there a survey you would find useful or an issue that could be resolved by a small, focussed collaborative study? Julie can be reached by email at


MEG News . topb(1).gif (622 bytes)

The Molecular Epidemiology Group held their Winter 1-day meeting entitled 'Gene-environment interactions' at the Scientific Societies' Lecture Theatre, London on Monday 22 November 1999. CRC and UKEMS are thanked for their sponsorship of this meeting, which was very successful. The topics included coronary artery disease (Prof Stephen Humphries, UCL, London), ionising radiation (Dr Janet Hall, IARC, France), and Parkinson's disease (Dr Nick Wood, UCL, London). The keynote lecture was given by Dr Douglas Bell (NIEHS, USA) on 'Genetic modulation of exposure-induced disease risk’.

The programme for the MEG workshop on Hazard and Risk at the Millennium meeting in Swansea (Monday 3 July 2000) has now been finalised and includes what should be an exciting and stimulating range of speakers. Dr Frank Duckworth (Royal Statistical Society) will speak on comparison of risks in our lives, followed by Prof Janet Bainbridge (University of Teeside) on the safety of genetically-modified food. Dr Joellen Lewtas (University of Washington, USA) and Prof David Kay (University of Aberystwyth) will talk about risks from air pollution and water respectively. The final invited speaker is Dr Jerry Rice (IARC, Lyon, France) who will show how data on mechanisms of carcinogenesis can be used for carcinogenic risk evaluation. The MEG AGM will be held during this meeting.

The most ambitious MEG meeting in 2000 is a BACR/UKEMS Molecular Epidemiology Group Special Conference on 'Applicability and relevance of methods used for molecular cancer epidemiology'. This will be held on 21-23 September 2000 at the beautiful location of the Low Wood Hotel, Lake Windermere, Cumbria. We are hoping for 75-100 participants. The speakers are all internationally recognised and most have already accepted invitations to attend. This workshop will be held in the style of a Gordon conference and should combine excellent science with an opportunity to enjoy the attractions of the Lake District. Further information is at the following web-site, which is available through the UKEMS' home page.

The 1-day MEG Winter meeting in 2000 is entitled ‘Infections’ and will be held at the Scientific Societies' Lecture Theatre, London on Monday 4 December. A programme is currently being prepared. Plans are still underway for participation in an international MEG meeting to be held in Italy, probably in the first week of May 2001.

For further information on any MEG activities, please contact Jenny Duckmanton, Dept of Biology, University of York, PO Box 373, York YO10 5YW - email


EEMS News . topb(1).gif (622 bytes)

The 30th Annual Meeting of the European Environmental Mutagenicity Society is to be held in Budapest, Hungary, between the 22nd and 26th of August 2000. The overall theme for the meeting is "Challenges of Mutation Research for the XXIst Century", and the four main session headings are: Mutagenesis and Carcinogenesis; Genes and Environmental Interactions; Risk Assessment; Ethical aspects. The venue for the meeting is the Thermal Hotel Helia, a mineral spa hotel on the banks of the river Danube. The First Announcement has previously been mailed, with a return date of 15 November 1999, in order to receive the Second Announcement containing further details of the meeting, in Jan 2000. The Meeting Secretariat and address for correspondence for requesting the second announcement appears in the "More meetings of Interest" section, below.

At the last business council meeting in Copenhagen it was decided to abolish the International Scientific Program Committee. The objective of this committee was to advise the organizers of the annual meeting as to the scientific content, but it was not effective as an advisory committee. For the future meetings, a scientific committee will consist of representatives for the local committee, the EEMS past president and chairmen of the relevant speciality sections. It was advised that national societies could influence the program by suggesting themes, symposia or specific speakers to the program. As chairman of the committee Herman Autrup I would like EEMS Councillors, on behalf of the national society, to make suggestions for the next annual meeting in Belgium in 2001. Proposals should be submitted to Professor Autrup before January 15.

A reminder, too, that we have a new EEMS Councillor in Barry Elliott, who has taken over this role from Jim Parry. If you have general comments, questions or suggestions about our field, or EEMS itself, please don’t hesitate to contact Barry. He can be reached by e-mail at or by fax on 01625 517 911.


Financial Matters . topb(1).gif (622 bytes)
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The Society's financial position has continued to strengthen, in particular following the outstanding success of UKEMS99 in Coleraine. Valerie McKelvey-Martin and her team put together a great conference both from the scientific and social aspects and managed to make a profit of 5000. With a healthy bank balance that looks set to keep on growing, we need to ensure that funds are released to further the aims of the Society. This mainly covers various bursaries, travel grants and awards aimed at the student membership. Any enquiries about how to claim awards should be forwarded to the Treasurer. All student members are encouraged to pursue this line of funding.

Other creative uses of our funding will continue to be discussed by the UKEMS committee and any suggestions will be gratefully received. Finally, another reminder that we have reviewed the conditions for sustaining membership. The annual fee will now be 500 and each Sustaining Member organisation will receive space on the UKEMS website, the opportunity to place a one-page flier in each Newsletter mailing, three free registrations at the annual meeting, acknowledgement in the meeting programme and, of course, the highly prized certificate.

Other Matters . topb(1).gif (622 bytes)
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As always, don’t forget that this Newsletter is a good opportunity to circulate information on vacancies, studentships, workshops, meetings etc, to all UKEMS members, and it’s free of charge to academic and non-profit organisations. We would also welcome other contributions, such as commentaries, opinions, reviews etc. which might interest our members and perhaps stimulate some discussion.

Steve Dean (Secretary)


More Meetings of Interest . topb(1).gif (622 bytes)
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19-23 March 2000, Philadelphia, USA, 39th Annual Meeting of the Society of Toxicology. (Contact SOT, 1767 Business Centre Drive, Suite 302, Reston, Virginia 22090-5332; Tel: +1 703 438 3115, Fax: +1 703 438 3113).

26-28 March 2000, University of York, British Toxicology Society Spring Meeting. (Contact Dr TJB Gray, Meetings Secretary, Sanofi Research, Willowburn Avenue, Alnwick, Northumberland NE66 2JH, England. Tel: +44 (0)1665 607370; Fax: +44 (0)1665 607510).

8-13 April 2000, New Orleans, USA, EMS Annual Meeting. (Contact Jim Tucker, e-mail: and website at

2-5 July 2000, Swansea, UKEMS Millennium Meeting, with sessions organised by both IGG and MEG (Contact Jim Parry, e-mail:

10-14 July 2000, Stresa, Lake Maggiore, Italy 13th International Symposium on microsomes and drug oxidations, MDO 2000. (Contact Prof Francesco De Matteis, Fax: +39 011 670 77 88; e-mail:

22-26 August 2000, 30th annual EEMS meeting, Budapest. Contact Diamond Congress Ltd, EEMS 2000, H-1027 Budapest, Fo u. 68, Hungary. Phone: +36-1-214 7701; Fax: +36-1-201 2680, E-mail: and the conference homepage is located at:

17-20 September 2000, London, EUROTOX 2000, the 38th Congress of the European Societies of Toxicology. (Contact the EUROTOX 2000 secretariat, Tel +44 20 8661 0877, Fax +44 20 8661 9036, e-mail:, or Alan Boobis, e-mail:

21-23 September 2000, Lake District, MEG/BACR Special Conference on Applicability and relevance of methods used for cancer epidemiology. (Contact Jenny Duckmanton, e-mail:

4 December 2000, London, MEG Winter meeting on the topic of infections. (Contact Jenny Duckmanton, e-mail:

26-29 March 2001, San Francisco, USA, 40th SOT.

May 2001, Rome, Italy, AACR MEG and European MEG joint meeting (Contact Jenny Duckmanton, e-mail:

 4-6 July 2001, Nottingham, UKEMS Annual Scientific Meeting (Contact Mike O’Donovan, e-mail: mike.o’

8-13 July 2001, Brisbane, Australia, 9th International Congress of Toxicology (Contact ASCEPT Secretariat, 145 Macquarie Street, Sydney, NSW 2000, Australia, Tel: +61 2 2565456; Fax: +61 2 2523310).

2001, ICEM, Japan.

18-22 March, 2002, Nashville, USA, 41st SOT.

1-3 July 2002, Plymouth, UKEMS Annual Scientific Meeting (Contact Awadhesh Jha)

July 2003, Aberdeen, EEMS Annual Scientific Meeting (Contact Andrew Collins)

2005, ICEM, USA.


Current Committee Members . topb(1).gif (622 bytes)
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Michael Green                      (President, 1998-2000)
Barry Elliott                          (Vice-President, 1998-2000, EEMS Councillor, 1999>)
Steve Dean                          (Secretary, 1996-2002)
Kevin Adams                       (Treasurer & Membership Secretary, 1995-2001)
Jim Parry                             (Mutagenesis Editor, <2000)
Peter Jenkinson                   (Seconded for Swansea 2000, 1999-2000)
Julie Clements                      (IGG chairperson, 1999-2002)
Peter Farmer                       (MEG Chairperson, 1998>)
Brian Burlinson                   (Committee Member, 1998-2001)
Mike O’Donovan                (Committee Member, 1998-2001)
Andrew Collins                   (Committee Member, 1999-2002)


Swansea 2000, UKEMS Annual Meeting

(December 1999, for July 2000 new members)


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For further information contact:
University of Wales Swansea