Dr Alan Williams
Professor
Medicine
Telephone: (01792) 513453
Room: Academic Office - 144
First Floor
Institute of Life Science 1
Singleton Campus

Publications

  1. & The ryanodine receptor: advances in structure and organization. Current Opinion in Physiology 1, 1-6.
  2. & Massive Accumulation of Myofibroblasts in the Critical Isthmus Is Associated With Ventricular Tachycardia Inducibility in Post-Infarct Swine Heart. JACC: Clinical Electrophysiology 3(7), 703-714.
  3. & Questioning flecainide's mechanism of action in the treatment of catecholaminergic polymorphic ventricular tachycardia. The Journal of Physiology 594(21), 6431-6432.
  4. & Unambiguous observation of blocked states reveals altered, blocker-induced, cardiac ryanodine receptor gating. Scientific Reports 6(1)
  5. & Structural insights into Ca2+-activated long-range allosteric channel gating of RyR1. Cell Research 26(9), 977-994.

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Teaching

  • PM-266 The Cardiovascular System

    Leading on from the first year Human Physiology Module (PM-139), the Cardiovascular Module will introduce and define the fundamental cellular mechanisms that regulate the physiology of healthy cardiovascular function. The Module will describe the processes that allow regular heartbeat and blood vessel function and how perturbations in the systems covered may lead to pathophysiological conditions. There will be an emphasis on experimental approaches used to study the cardiovascular mechanisms described.