Publications

Journal Articles

  1. & Comparison of the composition of bile acids in bile of patients with adenocarcinoma of the pancreas and benign disease. The Journal of Steroid Biochemistry and Molecular Biology 174, 290-295.
  2. & Defective cholesterol metabolism in amyotrophic lateral sclerosis. Journal of Lipid Research 58(1), 267-278.
  3. & The role of microRNA-155/liver X receptor pathway in experimental and idiopathic pulmonary fibrosis. Journal of Allergy and Clinical Immunology 139(6), 1946-1956.
  4. & Reduced Plasma Levels of 25-Hydroxycholesterol and Increased Cerebrospinal Fluid Levels of Bile Acid Precursors in Multiple Sclerosis Patients. Molecular Neurobiology
  5. & Current trends in oxysterol research. Biochemical Society Transactions 44(2), 652-658.
  6. & Sterols and oxysterols in plasma from Smith-Lemli-Opitz syndrome patients. The Journal of Steroid Biochemistry and Molecular Biology
  7. et. al. An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway. PLOS Biology 14(3), e1002364
  8. & Revised sample preparation for the analysis of oxysterols by enzyme-assisted derivatisation for sterol analysis (EADSA). Analytical and Bioanalytical Chemistry 407(17), 5235-5239.
  9. & Cholesterol metabolites exported from human brain. Steroids 99, 189-193.
  10. & The oxysterol and cholestenoic acid profile of mouse cerebrospinal fluid. Steroids 99, 172-177.
  11. et. al. Cholestenoic acids regulate motor neuron survival via liver X receptors. Journal of Clinical Investigation 124(11), 4829-4842.
  12. & Quantitative Charge-Tags for Sterol and Oxysterol Analysis. Clinical Chemistry 61(2), 400-411.
  13. & Oxysterols in the brain of the cholesterol 24-hydroxylase knockout mouse. Biochemical and Biophysical Research Communications 446(3), 768-774.
  14. & Studies on the analysis of 25-hydroxyvitamin D3 by isotope-dilution liquid chromatography–tandem mass spectrometry using enzyme-assisted derivatisation. Biochemical and Biophysical Research Communications 446(3), 745-750.
  15. & Evaluation of novel derivatisation reagents for the analysis of oxysterols. Biochemical and Biophysical Research Communications 446(3), 756-761.
  16. & A new derivative for oxosteroid analysis by mass spectrometry. Biochemical and Biophysical Research Communications 446(3), 762-767.
  17. & Liver disease in infancy caused by oxysterol 7α-hydroxylase deficiency: successful treatment with chenodeoxycholic acid. Journal of Inherited Metabolic Disease 37(5), 851-861.
  18. et. al. Effects of a Disrupted Blood-Brain Barrier on Cholesterol Homeostasis in the Brain. Journal of Biological Chemistry 289(34), 23712-23722.
  19. et. al. On the formation of 7-ketocholesterol from 7-dehydrocholesterol in patients with CTX and SLO. The Journal of Lipid Research 55(6), 1165-1172.
  20. & 24S,25-Epoxycholesterol in mouse and rat brain. Biochemical and Biophysical Research Communications 449(2), 229-234.
  21. et. al. The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response. Immunity 38(1), 106-118.
  22. et. al. Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis. Nature Chemical Biology 9(2), 126-133.
  23. et. al. Shotgun cholanomics of ileal fluid. Biochimie 95(3), 461-463.
  24. & Methods for oxysterol analysis: Past, present and future. Biochemical Pharmacology 86(1), 3-14.
  25. & Analysis by liquid chromatography–mass spectrometry of sterols and oxysterols in brain of the newborn Dhcr7Δ3-5/T93M mouse: A model of Smith–Lemli–Opitz syndrome. Biochemical Pharmacology 86(1), 43-55.
  26. et. al. Synthesis and biological activity of (24E)- and (24Z)-26-hydroxydesmosterol. Bioorganic & Medicinal Chemistry 21(18), 5794-5798.
  27. & Nano-liquid chromatography–tandem mass spectrometry analysis of oxysterols in brain: monitoring of cholesterol autoxidation. Chemistry and Physics of Lipids 164(6), 411-424.
  28. & Are 15-oxygenated sterols present in the human circulation?. The Journal of Lipid Research 52(1), 4-5.
  29. & On the future of “omics”: lipidomics. Journal of Inherited Metabolic Disease 34(3), 583-592.
  30. et. al. Detecting oxysterols in the human circulation. Nature Immunology 12(7), 577-577.
  31. & Cerebrospinal Fluid Steroidomics: Are Bioactive Bile Acids Present in Brain?. Journal of Biological Chemistry 285(7), 4666-4679.
  32. & Cerebrospinal fluid steroidomics: Are bioactive bile acids present in brain. Journal of Biological Chemistry 285, 4666-79.
  33. & Sterol lipidomics in health and disease: Methodologies and applications. European Journal of Lipid Science and Technology 111(1), 14-38.
  34. & The Importance of Steroidomics in the Study of Neurodegenerative Disease and Ageing. Combinatorial Chemistry & High Throughput Screening 12(2), 212-228.
  35. & Mass spectrometry: from proteomics to metabolomics and lipidomics. Chemical Society Reviews 38(7), 1882
  36. & Analysis of neurosterols by GC–MS and LC–MS/MS. Journal of Chromatography B 877(26), 2778-2805.
  37. & Quantitative Proteomics Characterization of a Mouse Embryonic Stem Cell Model of Down Syndrome. Molecular & Cellular Proteomics 8(4), 585-595.
  38. & Multiple-Approaches to the Identification and Quantification of Cytochromes P450 in Human Liver Tissue by Mass Spectrometry.. J Proteome Res 8, 1672-81.
  39. & Targeted lipidomic analysis of oxysterols in the embryonic central nervous system. Molecular BioSystems 5, 529-41.
  40. & Multiple-Approaches to the Identification and Quantification of Cytochromes P450 in Human Liver Tissue by Mass Spectrometry. Journal of Proteome Research 8(4), 1672-1681.
  41. & Capillary liquid chromatography combined with tandem mass spectrometry for the study of neurosteroids and oxysterols in brain. Neurochemistry International 52(4-5), 506-521.
  42. & Potential of Sterol Analysis by Liquid Chromatography-Tandem Mass Spectrometry for the Prenatal Diagnosis of Smith-Lemli-Opitz Syndrome. Clinical Chemistry 54(8), 1317-1324.
  43. & The Effect of 24S-Hydroxycholesterol on Cholesterol Homeostasis in Neurons: Quantitative Changes to the Cortical Neuron Proteome. Journal of Proteome Research 7(4), 1606-1614.
  44. & Discovering Oxysterols in Plasma: A Window on the Metabolome. Journal of Proteome Research 7(8), 3602-3612.
  45. & Comparative Cytochrome P450 Proteomics in the Livers of Immunodeficient Mice Using18O Stable Isotope Labeling. Molecular & Cellular Proteomics 6(6), 953-962.
  46. & Modern Methods of Bile Acid Analysis by Mass Spectrometry: A View into the Metabolome. Current Analytical Chemistry 3(2), 103-126.
  47. & Analysis of neurosterols and neurosteroids by mass spectrometry. Biochimie 89(2), 182-191.
  48. & Metabolomics and metabolite profiling: past heroes and future developments. European Journal of Mass Spectrometry 13(1), 45
  49. & Liquid chromatography-mass spectrometry utilizing multi-stage fragmentation for the identification of oxysterols. The Journal of Lipid Research 48(4), 976-987.
  50. & Proteomic analysis of cytochromes P450: a mass spectrometry approach. Biochemical Society Transactions 34(6), 1246-1251.
  51. & Analysis of derivatised steroids by matrix-assisted laser desorption/ionisation and post-source decay mass spectrometry. Steroids 71(1), 42-53.
  52. & Matrix-Assisted Laser Desorption/Ionization High-Energy Collision-Induced Dissociation of Steroids:  Analysis of Oxysterols in Rat Brain. Analytical Chemistry 78(1), 164-173.
  53. & Analysis of oxysterols by electrospray tandem mass spectrometry. Journal of the American Society for Mass Spectrometry 17(3), 341-362.
  54. & Analysis of a 17-amino acid residue, virus-neutralizing microantibody. Journal of General Virology 86(6), 1791-1800.
  55. & Antibacterial Activities of the Cathelicidins Prophenin (Residues 62 to 79) and LL-37 in the Presence of a Lung Surfactant Preparation. Antimicrobial Agents and Chemotherapy 48(6), 2097-2100.
  56. & Antibacterial peptides in stimulated human granulocytes. European Journal of Biochemistry 269(2), 512-518.
  57. & Characterisation of variant forms of prophenin: mechanistic aspects of the fragmentation of proline-rich peptides. Rapid Communications in Mass Spectrometry 14(23), 2182-2202.
  58. & Porcine pulmonary surfactant preparations contain the antibacterial peptide prophenin and a C-terminal 18-residue fragment thereof. FEBS Letters 460(2), 257-262.
  59. & Apolipoprotein A-I Binds and Inhibits the Human Antibacterial/Cytotoxic Peptide LL-37. Journal of Biological Chemistry 273(50), 33115-33118.
  60. & Determination of Proteins, Phosphatidylethanolamine, and Phosphatidylserine in Organic Solvent Extracts of Tissue Material by Analysis of Phenylthiocarbamyl Derivatives. Analytical Biochemistry 265(1), 97-102.

Books

  1. & Mass Spectrometry Handbook.
  2. & Molecular Analysis and Genome Discovery.

Book Chapters

  1. & Targeted metabolomics and mass spectrometry. In -83).