Publications

  1. & Cytochrome P450 20A1 in zebrafish: Cloning, regulation and potential involvement in hyperactivity disorders. Toxicology and Applied Pharmacology 296, 73-84.
  2. & Genetic and structural analyses of cytochrome P450 hydroxylases in sex hormone biosynthesis: Sequential origin and subsequent coevolution. Molecular Phylogenetics and Evolution 94, 676-687.
  3. & Structure-Functional Characterization of Cytochrome P450 Sterol 14α-Demethylase (CYP51B) fromAspergillus fumigatusand Molecular Basis for the Development of Antifungal Drugs. Journal of Biological Chemistry 290(39), 23916-23934.
  4. & Azole Antifungal Agents To Treat the Human Pathogens Acanthamoeba castellanii and Acanthamoeba polyphaga through Inhibition of Sterol 14α-Demethylase (CYP51). Antimicrobial Agents and Chemotherapy 59(8), 4707-4713.
  5. & Identification, modeling and ligand affinity of early deuterostome CYP51s, and functional characterization of recombinant zebrafish sterol 14α-demethylase. Biochimica et Biophysica Acta (BBA) - General Subjects 1840(6), 1825-1836.

Supervision

  • 'Exploring the roles of novel secondary metabolites in streptomycetes' (awarded 2014)

    Student name:
    PhD
    Other supervisor: Prof David Lamb
    Other supervisor: Prof Paul Dyson
    Other supervisor: Prof Steven Kelly
  • Gene deletion studies in analysis of the role of cytochrome P450 in flaviolin metabolism in Streptomyces coelicolor. (awarded 2009)

    Student name:
    MPhil
    Other supervisor: Prof Steven Kelly
    Other supervisor: Prof David Lamb