Professor Venkat Kanamarlapudi

Professor Venkat Kanamarlapudi
Professor of Molecular Cell Biology
Swansea University Medical School
Telephone: (01792) 295012

Areas of Expertise

  • Cell Biology
  • Cell Signalling
  • Molecular Mechanisms of disease
  • Biochemistry
  • Molecular Biology
  • Diabetes
  • Cancer
  • Host pathogen interactions
  • Phagocytosis
  • Membrane trafficking
  • Drug discovery
  • Endocytosis
  • Glucagon like peptide-1 (GLP-1)
  • Arf6
  • G protein coupled receptor (GPCR)
  • Neuroscience

Publications

  1. & Luteinizing hormone/chorionic gonadotrophin receptor overexpressed in granulosa cells from polycystic ovary syndrome ovaries is functionally active. Reproductive BioMedicine Online
  2. & Molecular Characterisation of Small Molecule Agonists Effect on the Human Glucagon Like Peptide-1 Receptor Internalisation. PLOS ONE 11(4), e0154229
  3. & Signal transducer and activator of transcription-3 licenses Toll-like receptor 4-dependent interleukin (IL)-6 and IL-8 production via IL-6 receptor-positive feedback in endometrial cells. Mucosal Immunology
  4. & The regions within the N-terminus critical for human glucagon like peptide-1 receptor (hGLP-1R) cell Surface expression. Scientific Reports 4, 7410
  5. Exchange factor EFA6R requires C-terminal targeting to the plasma membrane to promote cytoskeletal rearrangement through the activation of ARF6. Journal of Biological Chemistry 289(48), 33378-33390.

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Teaching

  • PM-304 Biomolecular Research Project

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Supervision

  • Functional characterisation of EFA6R, a possible biomarker for ovarian cancer. (current)

    Student name:
    PhD
    Other supervisor: Prof Venkat Kanamarlapudi
    Other supervisor: Dr William Walker
  • Analysis of the effect of mechanical heart pumps on the blood components (current)

    Student name:
    PhD
    Other supervisor: Prof Venkat Kanamarlapudi
    Other supervisor: Dr Karl Hawkins
  • Studying the underlying mechanisms of the GLP-1 receptor agonists treatment for diabesity (current)

    Student name:
    PhD
    Other supervisor: Prof Venkat Kanamarlapudi
    Other supervisor: Prof Steve Bain
  • Targeting the interleukin-13 receptor (IL-13R)alpha2 expressing pancreatic cancer by a novel hybrid lytic peptide drug (current)

    Student name:
    PhD
    Other supervisor: Prof Venkat Kanamarlapudi
    Other supervisor: Dr William Walker
  • Untitled (current)

    Student name:
    PhD
    Other supervisor: Dr Lloyd Bridge
    Other supervisor: Prof Venkat Kanamarlapudi