Chris was born and brought up in the Cynon Valley and studied Biochemistry at Cardiff University. After a PhD investigating the role of calcium signals in regulating cell-to-cell communication, Chris moved into heart research at Cardiff University’s Medical School. Keen to take responsibility for his own mistakes, Chris got a British Heart Foundation Intermediate Fellowship in 2000. Successive BHF Lectureship and Senior Basic Science Research Fellowship awards between 2004 and 2015 funded him to combine new molecular and cellular imaging tools with network theory to explore the links between calcium signaling, cellular behavior and the early events leading to the destruction of normal heart rhythm. As a member of the Molecular Cardiology group, Chris became a Professor at Swansea University’s Medical School in 2017. His research is now focused on investigating the mechanisms that underpin the variability and predictability of response of populations of stem-cell derived heart cells to genetic mutations and drugs. The work will improve therapeutic approaches for tackling genetic and acquired heart disease and is also being incorporated into new frameworks for early drug screening and drug development. He is a Senior Editor of the British Journal of Pharmacology and is a member of the editorial board of Frontiers in Physiology and Artery Research. Chris currently serves on the grants assessment panel for the National Centre for Replacement, Refinement and Reduction of Animals in Research (NC3R).