Journal Articles

  1. & Respiratory hazard assessment of combined exposure to complete gasoline exhaust and respirable volcanic ash in a multicellular human lung model at the air-liquid interface. Environmental Pollution 238, 977-987.
  2. et. al. Current characterization methods for cellulose nanomaterials. Chemical Society Reviews 47(8), 2609-2679.
  3. & Biological response of an in vitro human 3D lung cell model exposed to brake wear debris varies based on brake pad formulation. Archives of Toxicology
  4. & Profibrotic Activity of Multiwalled Carbon Nanotubes Upon Prolonged Exposures in Different Human Lung Cell Types. Applied In Vitro Toxicology
  5. & Aligning nanotoxicology with the 3Rs: What is needed to realise the short, medium and long-term opportunities?. Regulatory Toxicology and Pharmacology 91, 257-266.
  6. & Nanomaterials Versus Ambient Ultrafine Particles: An Opportunity to Exchange Toxicology Knowledge. Environmental Health Perspectives 125(10)
  7. & Characteristics and properties of nano-LiCoO2 synthesized by pre-organized single source precursors: Li-ion diffusivity, electrochemistry and biological assessment. Journal of Nanobiotechnology 15(1)
  8. & Abstracts of the 40th Annual Meeting of the United Kingdom Environmental Mutagen Society, 25th–28th June 2017 at the Park Inn Hotel, Leuven, Belgium. Mutagenesis 32(6), 607-628.
  9. & A novel technique to determine the cell type specific response within an in vitro co-culture model via multi-colour flow cytometry. Scientific Reports 7(1)
  10. & Human Asthmatic Bronchial Cells Are More Susceptible to Subchronic Repeated Exposures of Aerosolized Carbon Nanotubes At Occupationally Relevant Doses Than Healthy Cells. ACS Nano 11(8), 7615-7625.
  11. & The 3Rs as a framework to support a 21st century approach for nanosafety assessment. Nano Today 12, 10-13.
  12. & Critical review of the current and future challenges associated with advanced in vitro systems towards the study of nanoparticle (secondary) genotoxicity. Mutagenesis 32(1), 233-241.
  13. & Combined exposure of diesel exhaust particles and respirable Soufrière Hills volcanic ash causes a (pro-)inflammatory response in an in vitro multicellular epithelial tissue barrier model. Particle and Fibre Toxicology 13(1)
  14. & A critical review of the current knowledge regarding the biological impact of nanocellulose. Journal of Nanobiotechnology 14(1)
  15. & Decoupling the shape parameter to assess gold nanorod uptake by mammalian cells. Nanoscale 8(36), 16416-16426.
  16. & Synthesis, characterization, antibacterial activity and cytotoxicity of hollow TiO2-coated CeO2nanocontainers encapsulating silver nanoparticles for controlled silver release. J. Mater. Chem. B 4(6), 1166-1174.
  17. & Elucidating the Potential Biological Impact of Cellulose Nanocrystals. Fibers 4(3), 21
  18. & Nanofibers: Friend or Foe?. Fibers 4(3), 25
  19. & A biological perspective toward the interaction of theranostic nanoparticles with the bloodstream – what needs to be considered?. Frontiers in Chemistry 3
  20. & Uptake efficiency of surface modified gold nanoparticles does not correlate with functional changes and cytokine secretion in human dendritic cells in vitro. Nanomedicine: Nanotechnology, Biology and Medicine 11(3), 633-644.
  21. & Uptake and Intracellular Fate of Peptide Surface-Functionalized Silica Hybrid Magnetic Nanoparticles In Vitro. Particle & Particle Systems Characterization 32(2), 188-196.
  22. & Repeated exposure to carbon nanotube-based aerosols does not affect the functional properties of a 3D human epithelial airway model. Nanotoxicology 9(8), 983-993.
  23. & Investigating the role of shape on the biological impact of gold nanoparticlesin vitro. Nanomedicine 10(17), 2643-2657.
  24. Gagnon, J., Clift, M.J.D., Vanhecke, D., Kuhn, D.A., Weber, P., Petri-Fink, A., Rothen-Rutishauser, B., Fromm, K.M. Integrating silver compounds and nanoparticles into ceria nanocontainers for antimicrobial applications. J. Mater. Chem. B 3(9), 1760-1768.
  25. & Fate of Cellulose Nanocrystal Aerosols Deposited on the Lung Cell Surface In Vitro. Biomacromolecules 16(4), 1267-1275.
  26. & Assessment of a panel of interleukin-8 reporter lung epithelial cell lines to monitor the pro-inflammatory response following zinc oxide nanoparticle exposure under different cell culture conditions. Particle and Fibre Toxicology 12(1)
  27. Vanhecke, D., Rodriguez-Lorenzo, L., Clift, M.J.D., Blank, F., Petri-Fink, A., Rothen-Rutishauser, B. Quantification of nanoparticles at the single-cell level: an overview about state-of-the-art techniques and their limitations. Nanomedicine 9(12), 1885-1900.
  28. & Polyvinyl Alcohol as a Biocompatible Alternative for the Passivation of Gold Nanorods. Angewandte Chemie International Edition 53, n/a-n/a.
  29. & Modeling Nanoparticle–Alveolar Epithelial Cell Interactions under Breathing Conditions Using Captive Bubble Surfactometry. Langmuir 30(17), 4924-4932.
  30. Carrillo-Carrión, C., Nazarenus, M., Paradinas, S.S., Carregal-Romero, S., Almendral, M.J., Fuentes, M., Pelaz, B., Del Pino, P., Hussain, I., Clift, M.J.D., Rothen-Rutishauser, B., Liang, X.-J., Parak, W.J. Metal ions in the context of nanoparticles toward biological applications. Current Opinion in Chemical Engineering 4, 88-96.
  31. Nazarenus, M., Zhang, Q., Soliman, M.G., del Pino, P., Pelaz, B., Carregal-Romero, S., Rejman, J., Rothen-Rutishauser, B., Clift, M.J.D., Zellner, R., Nienhaus, G.U., Delehanty, J.B., Medintz, I.L., Parak, W.J. In vitro interaction of colloidal nanoparticles with mammalian cells: What have we learned thus far?. Beilstein Journal of Nanotechnology 5, 1477-1490.
  32. & An in vitro testing strategy towards mimicking the inhalation of high aspect ratio nanoparticles. Particle and Fibre Toxicology 11(1)
  33. & A Comparative Study of Different In Vitro Lung Cell Culture Systems to Assess the Most Beneficial Tool for Screening the Potential Adverse Effects of Carbon Nanotubes. Toxicological Sciences 137(1), 55-64.
  34. & Mimicking exposures to acute and lifetime concentrations of inhaled silver nanoparticles by two different in vitro approaches. Beilstein Journal of Nanotechnology 5, 1357-1370.
  35. Hirsch, V., Kinnear, C., Moniatte, M., Rothen-Rutishauser, B., Clift, M.J.D., Fink, A. Surface charge of polymer coated SPIONs influences the serum protein adsorption, colloidal stability and subsequent cell interaction in vitro. Nanoscale 5(9), 3723
  36. Endes, C., Müller, S., Schmid, O., Vanhecke, D., Foster, E.J., Petri-Fink, A., Rothen-Rutishauser, B., Weder, C., Clift, M.J.D. Risk assessment of released cellulose nanocrystals – mimicking inhalatory exposure. Journal of Physics: Conference Series 429, 012008
  37. Jud, C., Clift, M.J.D., Petri-Fink, A., Rothen-Rutishauser, B. Nanomaterials and the human lung: what is known and what must be deciphered to realise their potential advantages?. Swiss Medical Weekly 143
  38. Kinnear, C., Dietsch, H., Clift, M.J.D., Endes, C., Rothen-Rutishauser, B., Petri-Fink, A. Gold Nanorods: Controlling Their Surface Chemistry and Complete Detoxification by a Two-Step Place Exchange. Angewandte Chemie International Edition 52(7), 1934-1938.
  39. Herzog, F., Clift, M.J.D., Piccapietra, F., Behra, R., Schmid, O., Petri-Fink, A., Rothen-Rutishauser, B. Exposure of silver-nanoparticles and silver-ions to lung cells in vitro at the air-liquid interface. Particle and Fibre Toxicology 10(1), 11
  40. Clift, M.J.D., Raemy, D.O., Endes, C., Ali, Z., Lehmann, A.D., Brandenberger, C., Petri-Fink, A., Wick, P., Parak, W.J., Gehr, P., Schins, R.P.F., Rothen-Rutishauser, B. Can the Ames test provide an insight into nano-object mutagenicity? Investigating the interaction between nano-objects and bacteria. Nanotoxicology 7(8), 1373-1385.
  41. Behra, R., Sigg, L., Clift, M.J.D., Herzog, F., Minghetti, M., Johnston, B., Petri-Fink, A., Rothen-Rutishauser, B. Bioavailability of silver nanoparticles and ions: from a chemical and biochemical perspective. Journal of The Royal Society Interface 10(87), 20130396-20130396.
  42. Clift, M.J.D., Stone, V. Quantum Dots: An Insight and Perspective of Their Biological Interaction and How This Relates to Their Relevance for Clinical Use. Theranostics 2(7), 668-680.
  43. Gasser, M., Wick, P., Clift, M.J.D., Blank, F., Diener, L., Yan, B., Gehr, P., Krug, H.F., Rothen-Rutishauser, B. Pulmonary surfactant coating of multi-walled carbon nanotubes (MWCNTs) influences their oxidative and pro-inflammatory potential in vitro. Particle and Fibre Toxicology 9(1), 17
  44. Rivera-Gil, P., Clift, M.J., Rutishauser, B.R., Parak, W.J. Methods for understanding the interaction between nanoparticles and cells.. Methods in molecular biology (Clifton, N.J.) 926
  45. Solomon, P.A., Gehr, P., Bennett, D.H., Phalen, R.F., Méndez, L.B., Rothen-Rutishauser, B., Clift, M., Brandenberger, C., Mühlfeld, C. Macroscopic to microscopic scales of particle dosimetry: from source to fate in the body. Air Quality, Atmosphere & Health 5(2), 169-187.
  46. Müller, L., Comte, P., Czerwinski, J., Kasper, M., Mayer, A.C.R., Schmid, A., Rosinus, L., Clift, M.J.D., Steiner, S., Gehr, P., Rothen-Rutishauser, B. Investigating the potential for different scooter and car exhaust emissions to cause cytotoxic and (pro-)inflammatory responses to a 3Din vitromodel of the human epithelial airway. Toxicological & Environmental Chemistry 94(1), 164-180.
  47. Raemy, D.O., Grass, R.N., Stark, W.J., Schumacher, C.M., Clift, M.J.D., Gehr, P., Rothen-Rutishauser, B. Effects of flame made zinc oxide particles in human lung cells - a comparison of aerosol and suspension exposures. Particle and Fibre Toxicology 9(1), 33
  48. Steiner, S., Mueller, L., Popovicheva, O.B., Raemy, D.O., Czerwinski, J., Comte, P., Mayer, A., Gehr, P., Rothen-Rutishauser, B., Clift, M.J.D. Cerium dioxide nanoparticles can interfere with the associated cellular mechanistic response to diesel exhaust exposure. Toxicology Letters 214(2), 218-225.
  49. Van Berlo, D., Clift, M., Albrecht, C., Schins, R. Carbon nanotubes: an insight into the mechanisms of their potential genotoxicity. Swiss Medical Weekly 142
  50. Griffete, N., Clift, M.J.D., Lamouri, A., Digigow, R.G., Mihut, A.M., Fink, A., Rothen-Rutishauser, B., Dietsch, H. Amino covalent binding approach on iron oxide nanoparticle surface: Toward biological applications. Colloids and Surfaces A: Physicochemical and Engineering Aspects 415, 98-104.
  51. Clift, M.J.D., Brandenberger, C., Rothen-Rutishauser, B., Brown, D.M., Stone, V. The uptake and intracellular fate of a series of different surface coated quantum dots in vitro. Toxicology 286(1-3), 58-68.
  52. Clift, M.J.D., Varet, J., Hankin, S.M., Brownlee, B., Davidson, A.M., Brandenberger, C., Rothen-Rutishauser, B., Brown, D.M., Stone, V. Quantum dot cytotoxicityin vitro: An investigation into the cytotoxic effects of a series of different surface chemistries and their core/shell materials. Nanotoxicology 5(4), 664-674.
  53. Clift, M.J.D., Gehr, P., Rothen-Rutishauser, B. Nanotoxicology: a perspective and discussion of whether or not in vitro testing is a valid alternative. Archives of Toxicology 85(7), 723-731.
  54. Bouwmeester, H., Lynch, I., Marvin, H.J.P., Dawson, K.A., Berges, M., Braguer, D., Byrne, H.J., Casey, A., Chambers, G., Clift, M.J.D., Elia, G., Fernandes, T.F., Fjellsbø, L.B., Hatto, P., Juillerat, L., Klein, C., Kreyling, W.G., Nickel, C., Riediker, M., Stone, V. Minimal analytical characterization of engineered nanomaterials needed for hazard assessment in biological matrices. Nanotoxicology 5(1), 1-11.
  55. Clift, M.J.D., Foster, E.J., Vanhecke, D., Studer, D., Wick, P., Gehr, P., Rothen-Rutishauser, B., Weder, C. Investigating the Interaction of Cellulose Nanofibers Derived from Cotton with a Sophisticated 3D Human Lung Cell Coculture. Biomacromolecules 12(10), 3666-3673.
  56. Wick, P., Clift, M.J.D., Rösslein, M., Rothen-Rutishauser, B. A Brief Summary of Carbon Nanotubes Science and Technology: A Health and Safety Perspective. ChemSusChem 4(7), 905-911.
  57. Clift, M.J.D., Bhattacharjee, S., Brown, D.M., Stone, V. The effects of serum on the toxicity of manufactured nanoparticles. Toxicology Letters 198(3), 358-365.
  58. Rothen-Rutishauser, B., Lehmann, A.D., Clift, M.J.D., Blank, F., Gehr, P. Laser scanning microscopy combined with image restoration to analyse a 3D model of the human epithelial airway barrier. Swiss Medical Weekly 140
  59. Brandenberger, C., Clift, M.J.D., Vanhecke, D., Mühlfeld, C., Stone, V., Gehr, P., Rothen-Rutishauser, B. Intracellular imaging of nanoparticles: Is it an elemental mistake to believe what you see?. Particle and Fibre Toxicology 7(1), 15
  60. Clift, M.J.D., Boyles, M.S.P., Brown, D.M., Stone, V. An investigation into the potential for different surface-coated quantum dots to cause oxidative stress and affect macrophage cell signallingin vitro. Nanotoxicology 4(2), 139-149.
  61. Clift, M.J.D., Rothen-Rutishauser, B., Brown, D.M., Duffin, R., Donaldson, K., Proudfoot, L., Guy, K., Stone, V. The impact of different nanoparticle surface chemistry and size on uptake and toxicity in a murine macrophage cell line. Toxicology and Applied Pharmacology 232(3), 418-427.
  62. Stone, V., Johnston, H., Clift, M.J.D. Air Pollution, Ultrafine and Nanoparticle Toxicology: Cellular and Molecular Interactions. IEEE Transactions on NanoBioscience 6(4), 331-340.

Book Chapters

  1. & Overview of the current knowledge and challenges associated with human exposure to nanomaterials. In Biocatalysis & Nanotechnology. (pp. 775-809).
  2. & An overview of nanoparticle biocompatibility for their use in Nanomedicine. In Cornier, Jean / Owen, Andrew / Kwade, Arno / Van de Voorde, Marcel (Ed.), Pharmaceutical Nanotechnology. (pp. 443-468). Wiley.
  3. & Cellular uptake and intracellular trafficking of nanoparticles. In Nanoparticles in the Lung: Environmental Exposure and Drug Delivery. (pp. 147-166).
  4. & Studying the oxidative stress paradigm in vitro: A theoretical and practical perspective. In Methods in Molecular Biology.
  5. & Bio-Nanotechnology. In Nanoparticle-Lung Interactions and Their Potential Consequences for Human Health. (pp. 749-775).
  6. & Methods for understanding the interaction between nanoparticles and cells. In Methods in Molecular Biology.
  7. & Endocytosis of environmental and engineered micro- and nanosized particles.. In Comprehensive Physiology.
  8. & Endocytosis of environmental and engineered micro- and nanosized particles.. In Comprehensive Physiology. (pp. 1159-1174).
  9. & Human and natural environment effects of nanomaterials. In Sattler K D (Ed.), Handbook of Nanophysics. (pp. 14.1-14.26).
  10. & Environmental and Human Health Impacts of Nanotechnology. In Human Toxicology and Effects of Nanoparticles. (pp. 357-388).
  11. & Nanoparticle toxicology and ecotoxicology: The role of oxidative stress. In Zhao, Y. and Nalwa, H. S. (Ed.), Nanotoxicology. (pp. 281-296).

Conference Contributions

  1. & (2017). In Vitro mechanistic toxicology assessment of the potential hazard posed by few-layer graphene. Presented at Mutagenesis,, 620-621.
  2. & (2016). Environmental and anthropogenic factors affecting the respiratory toxicity of volcanic ash in vitro. Presented at Presented at EGU General Assembly/Geophysical Research Abstracts,, EGU2016-7855-1EGU General Assembly/Geophysical Research Abstracts.
  3. & (2016). Correlating the cytotoxic and genotoxic potential of few-layer graphene flakes with their physicochemical features. Presented at Presented at UKEMS/Mutagenesis,(6), 722-723.United Kingdom Environmental Mutagenesis Society Conference 2016.
  4. & (2015). Can a human 3D in vitro lung model be considered as a predictive tool for inhalation toxicology?;. Presented at 20th Meeting of the International Society for Aerosols in Medicine (ISAM)/ Journal of Aerosol Medicine and Pulmonary Drug Delivery,(3), A-30-A-30. doi:10.1089/jamp.2015.ab01.abstracts
  5. & (2015). A model next-level in vitro strategy to assess the inhalatory hazard of nanofibres.. Presented at In Vitro Toxicology Society (IVTS) UK/ Applied In Vitro Toxicology,(4), A3-A3.
  6. (2014). The role of oxidative stress in nanomaterial related genotoxicity in vitro.. Presented at 43rd Annual Meeting of the European Environmental Mutagen Society (EEMS)/ Mutagenesis,(6), 497-559. doi:10.1093/mutage/geu053
  7. & (2014). Next-level in vitro testing strategy to study the effects of carbon nanotube aerosols.. Presented at 9th World Congress on Alternatives to Animal Testing/ ALTEX,, 144-145.
  8. & (2014). Determination of advanced in vitro systems as valid, alternative test models to assess the potential genotoxicity of carbon nanotubes.
  9. & (2013). Efficiency and efficacy of using a sophisticated 3D in vitro system of the human epithelial airway barrier to gain insight into the hazard posed by nanomaterials. Presented at 49th Association of European Toxicologists and European Societies of Toxicology (EUROTOX) Meeting/ Toxicology Letters,, S146-S147. doi:10.1016/j.toxlet.2013.05.296
  10. Clift, M.J.D., Gehr, P., Rothen-Rutishauser, B. (2011). State of the art toxicological and microscopic assessment of biomedical nanocrystals on the lung in vitro. Presented at Progress in Biomedical Optics and Imaging - Proceedings of SPIE, doi:10.1117/12.875369
  11. & (2011). Comparing the interaction of silver and gold nanoparticles with a 3D model of the epithelial airway barrier. Presented at Journal of Aerosol Medicine and Pulmonary Drug Delivery,(3), A-54-A-54. doi:10.1089/jamp.2011.00A1
  12. & (2011). Exposure of primary macrophages to different functionalized multi-walled carbon nanotubes in vitro: What is the function of the pulmonary surfactant?. Presented at Journal of Aerosol Medicine and Pulmonary Drug Delivery,(3), A-52-A-52. doi:10.1089/jamp.2011.00A1
  13. & (2011). Comparing the effects of zinc oxide nanoparticles when exposed to human lung cells as either an aerosol or in suspension.. Presented at Journal of Aerosol Medicine and Pulmonary Drug Delivery,(3), A-52-A-52. doi:10.1089/jamp.2011.00A1
  14. & (2011). Investigating the effects of cerium dioxide and diesel exhaust co-exposure to the epithelial airway barrier at the air-liquid interface in vitro. Presented at Journal of Aerosol Medicine and Pulmonary Drug Delivery,(3), A-18-A-18. doi:10.1089/jamp.2011.00A1
  15. & (2011). Air-liquid exposure of particles onto lung culture surfaces: A new standard to study particle-cell interactions.. Presented at Journal of Aerosol Medicine and Pulmonary Drug Delivery,(3), A-13-A-13. doi:10.1089/jamp.2011.00A1
  16. & (2011). An evaluation of the potential for inhaled xenobiotics to develop cancer in the lung using a 3D in vitro model of the human epithelial airway-wall. Presented at European Respiratory Society Meeting/ European Respiratory Journal,(Supp 55), 2783
  17. & (2010). Mucosal perspectives in pneumococcal vaccine development: A meeting summary. Presented at Pneumococcal Vaccine Conference/ Vaccine,(1), 2-6. doi:10.1016/j.vaccine.2009.09.048
  18. & (2010). A sophisticated model of the human epithelial airway barrier to study uptake, cell responses and intracellular distribution of nanoparticles. Presented at 3rd International NanoBio Conference/ European Cells and Materials,, 216
  19. & (2010). Dynamics of the interaction of particulate matter with the internal lung surface: a model. Presented at Inflammation Research,(S1), s101-s101. doi:10.1007/s00011-010-0170-z
  20. & (2009). First Approaches to Standard Protocols and Reference Materials for the Assessment of Potential Hazards Associated with Nanomaterials.. European Union Joint Research Centre, Institute for Reference Materials and Measurements, JRC52094.
  21. & (2009). An in vitro model of the human epithelial airway barrier to study the toxicity of nanoparticles. Presented at 46th Congress of the European Societies of Toxicology/ Toxicology Letters,, S35-S36. doi:10.1016/j.toxlet.2009.06.074
  22. & (2006). Proinflammatory and toxicological effects of zinc and nanoparticle interactions are induced via nonoxidative mechanisms. Presented at British Toxicology Society/ Toxicology,, 230-242.Elsevier. doi:10.1016/j.tox.2005.10.021

Other Research Outputs

  1. & (2013). Gold Nanorods: Controlling their Surface Chemistry and Complete Detoxification by a Two-Step Place Exchange. (Chimia No. 67).