Publications

Journal Articles

  1. & Questioning flecainide's mechanism of action in the treatment of catecholaminergic polymorphic ventricular tachycardia. The Journal of Physiology 594(21), 6431-6432.
  2. & Pleiotropic mechanisms of action of perhexiline in heart failure. Expert Opinion on Therapeutic Patents 26(9), 1049-1059.
  3. & Effect of flecainide derivatives on sarcoplasmic reticulum calcium release suggests a lack of direct action on the cardiac ryanodine receptor. British Journal of Pharmacology 173(15), 2446-2459.
  4. & The Mechanism of Flecainide Action in CPVT Does Not Involve a Direct Effect on RyR2. Circulation Research 116(8), 1324-1335.
  5. & The contribution of hydrophobic residues in the pore-forming region of the ryanodine receptor channel to block by large tetraalkylammonium cations andShakerB inactivation peptides. The Journal of General Physiology 140(3), 325-339.
  6. & SERCA2a Gene Transfer Decreases Sarcoplasmic Reticulum Calcium Leak and Reduces Ventricular Arrhythmias in a Model of Chronic Heart Failure. Circulation: Arrhythmia and Electrophysiology 4(3), 362-372.
  7. & Amyloid-β protein impairs Ca2+ release and contractility in skeletal muscle. Neurobiology of Aging 31(12), 2080-2090.
  8. & Endoplasmic Reticulum Stress as a Novel Therapeutic Target in Heart Diseases. Cardiovascular & Hematological Disorders-Drug Targets 7(3), 205-218.
  9. & Peptide Probe Study of the Role of Interaction between the Cytoplasmic and Transmembrane Domains of the Ryanodine Receptor in the Channel Regulation Mechanism†. Biochemistry 46(14), 4272-4279.
  10. & Malignant hyperthermia mutation sites in the Leu2442–Pro2477(DP4) region of RyR1 (ryanodine receptor 1) are clustered in a structurally and functionally definable area. Biochemical Journal 401(1), 333-339.
  11. & Effects of peptide C corresponding to the Glu724–Pro760region of the II–III loop of the DHP (dihydropyridine) receptor α1 subunit on the domain- switch-mediated activation of RyR1 (ryanodine receptor 1) Ca2+channels. Biochemical Journal 394(1), 145-152.
  12. & Dantrolene Stabilizes Domain Interactions within the Ryanodine Receptor. Journal of Biological Chemistry 280(8), 6580-6587.
  13. & Activation of the sheep cardiac Ca2+ release channel by simple heteroaromatics. Biochemical and Biophysical Research Communications 317(2), 397-400.
  14. & Removal of clustered positive charge from dihydropyridine receptor II–III loop peptide augments activation of ryanodine receptors. Biochemical and Biophysical Research Communications 314(3), 667-674.
  15. & Conformation and Ion-Channeling Activity of a 27-Residue Peptide Modeled on the Single-Transmembrane Segment of the IsK (minK) Protein†,‡. Biochemistry 37(22), 8121-8131.