Dr William Walker
Senior Lecturer
Swansea University Medical School
Telephone: (01792) 513482

Areas of Expertise

  • immunology
  • allergy
  • siRNA
  • preclinical

Publications

  1. Development of Pre-Clinical Models for Evaluating the Therapeutic Potential of Candidate siRNA Targeting STAT6. PLoS ONE 9(2), e90338
  2. & Evaluation of nasal epithelium sampling as a tool in the preclinical development of siRNA-based therapeutics for asthma. Journal of Cellular and Molecular Medicine 17(3), 356-364.
  3. & Identification of small interfering RNA targeting signal transducer and activator of transcription-6: characterisation and selection of candidates for pre-clinical development. J. RNAi Gene Silencing 6, 401-10.
  4. & RNA interference of STAT6 rapidly attenuates ongoing interleukin-13-mediated events in lung epithelial cells. Immunology 127, 256-266.
  5. Variation in dinucleotide (GT) repeat sequence in the first exon of the STAT6 gene is associated with atopic asthma and differentially regulates the promoter activity in vitro. Journal of Medical Genetics 41(7), 535-539.

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Teaching

  • PM-304 Biomolecular Research Project

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Supervision

  • Functional characterisation of EFA6R, a possible biomarker for ovarian cancer. (current)

    Student name:
    PhD
    Other supervisor: Prof Venkat Kanamarlapudi
    Other supervisor: Dr William Walker
  • Targeting the interleukin-13 receptor (IL-13R)alpha2 expressing pancreatic cancer by a novel hybrid lytic peptide drug (current)

    Student name:
    PhD
    Other supervisor: Prof Venkat Kanamarlapudi
    Other supervisor: Dr William Walker