Geertje is an Associate Professor in the Institute of Life Science in the Medical School. Geertje’s research focuses on the microbiology of natural antibiosis and resistance to antibiotics and metals, microbial adaptation to drought and bioengineering of water repellency of manmade and natural materials. Her research team works in highly interdisciplinary collaborative projects with soil scientists, materials engineers, hydrologists, nanotechnologists and modellers funded by NERC, EPSRC and the Royal Society. Geertje is a lecturer for our Biochemistry Degree programme and the lead-organiser of Soapbox Science Swansea, an annual public beach science event showcasing the exciting research of women in STEM subjects, and founder member of SwanSTEMWoMen. Geertje tweets about her and other science interests from @GeertjevanK.

Areas of Expertise

  • microbiology
  • biochemistry
  • physiology
  • soil sciences
  • antibiotics
  • streptomyces
  • primary and specialized (secondary) metabolism
  • natural products
  • water repellency
  • bio-organic and protein coatings
  • proteomics
  • soil and metaproteomics
  • metabolomics
  • interdisciplinary sciences
  • functional amyloid proteins
  • C1 metabolism

Publications

  1. & The Family Streptomycetaceae. In Eugene Rosenberg, Edward F. DeLong, Stephen Lory, Erko Stackebrandt, Fabiano Thompson (Ed.), The Prokaryotes. (pp. 889-1010). Berlin Heidelberg: Springer.
  2. & Microbial modulation of soil ecosystem processes. Microbiology Today 42(2), 62-65.
  3. & The integration of nanoscale imaging and quantitation of nanomechanical properties in microbiology. Microbiology Today 43(3), 106-109.
  4. (2016). From nostrils to crocodile blood – ten surprising places to look for antibiotics. (The Conversation).
  5. & Production of Specialized Metabolites by Streptomyces coelicolor A3(2). In Sima Sariaslani and Geoffrey Michael Gadd (Ed.), (pp. 217-266). Elsevier Inc.

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Teaching

  • PM-130 Biochemistry Skills Development

    This module is designed to develop the skills required for students of biochemistry and medical biochemistry. Students meet with their tutors and will be given a series of assignments designed to develop skills in key areas such as essay writing, presentations and general numeracy. Joint session cover generic skills such as internet searching for scientific sources, referencing and plagiarism

  • PM-131 Chemistry of Life

    The module provides a broad study of the interactions between chemical processes and biological systems. It addresses the chemical processes used by organisms to utilize chemicals for energy production, structural functions and as building blocks of macromolecules.

  • PM-240 Carbohydrate Metabolism and Glycobiology

    Saccharides are the major source of energy and carbon that is used by the cell for growth and maintenance. The central roles of glycolysis in providing cellular energy and components from saccharides substrates, and the regulation of these processes are explained. The relationship between glycolysis and glycogen metabolism in mammals is explored as one of the ways in which substrate supply to the pathway is regulated. The complexity of the mechanisms, including hormonal, for controlling glycolysis and gluconeogenesis in mammalian to maintain blood concentrations is compared to glycogen and glucose metabolism in muscle tissue. The role or glycosyltransferases in the synthesis of oligo- and polysaccharides, including glycoprotein assembly, is also explained.

  • PM-245 Metabolic Regulation: Enzymes & Signal Transduction

    This module reviews the basic elements of enzyme kinetics, including their mechanism and inhibition. The control of enzyme function by allosteric mechanisms is considered together with an appreciation of the significance of sigmoid kinetics. An overview of coenzymes and (metal) co-factors in enzyme function is given together with a description of the role played by vitamins in co-enzyme production. The module concludes with an overview of enzymes from extremophiles and their applications.

  • PM-246 Biochemistry Skills Development II

    This module is designed to develop the skills required for students of biochemistry. Students meet with tutors and will be given a series of assignments designed to develop skills in key areas including essay writing, presentation and analysis of research papers.

  • PM-246C Datblygu Sgiliau Biocemeg II

    Nod y modiwl hwn yw datblygu'r sgiliau mae eu hangen ar fyfyrwyr biocemeg. Bydd myfyrwyr yn cwrdd â thiwtoriaid ac yn derbyn cyfres o aseiniadau at ddiben datblygu eu sgiliau mewn meysydd allweddol, gan gynnwys ysgrifennu traethodau, cyflwyno a dadansoddi papurau ymchwil.

  • PM-304 Biomolecular Research Project

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  • PM-314 Biotechnology & Protein Engineering

    The module aims to explain the biological basis of biotechnology and protein engineering: their limitations, industrial and medical importance. Students will develop their skills in gathering and interpreting relevant information.

  • PM-334 Biochemistry Literature Review and Communication

    Students will acquire a detailed knowledge of one topical research area of key importance to their particular degree scheme.

Supervision

  • Development of bio-organic coatings for sustainable pre-finished steels (current)

    Student name:
    EngD
    Other supervisor: Dr Geertje Van Keulen
    Other supervisor: Prof James Sullivan
  • Mass Spectromic investigation of pharmaceuticals in environmental matrices: homogenate analysis (current)

    Student name:
    PhD
    Other supervisor: Dr Ruth Godfrey
    Other supervisor: Dr Geertje Van Keulen
    Other supervisor: Prof Anthony Brenton
  • Study of the correlation between heavy metal content in polluted soils and antibiotic and heavy metal resistance and siderophore/antibiotics biosynthesis. (current)

    Student name:
    PhD
    Other supervisor: Dr Geertje Van Keulen
    Other supervisor: Dr Ricardo Del Sol Abascal