Publications

Journal Articles

  1. & Tissue-Engineered Solutions in Plastic and Reconstructive Surgery: Principles and Practice. 4
  2. & Investigation of J-shaped dose-responses induced by exposure to the alkylating agent N -methyl- N -nitrosourea. Mutation Research/Genetic Toxicology and Environmental Mutagenesis
  3. & Choose your cell model wisely: The in vitro nanoneurotoxicity of differentially coated iron oxide nanoparticles for neural cell labeling. Acta Biomaterialia
  4. & Genetic toxicity assessment of engineered nanoparticles using a 3D in vitro skin model (EpiDerm™). Particle and Fibre Toxicology 13(1)
  5. & Coating of Quantum Dots strongly defines their effect on lysosomal health and autophagy. Acta Biomaterialia
  6. Opinion of the Scientific Committee on consumer safety (SCCS) - Opinion on the use of 2,2′-methylene-bis-(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol) (nano) – S79 – In cosmetic products. Regulatory Toxicology and Pharmacology 76, 215-216.
  7. Wills JW, Johnson GE, Doak SH, Soeteman-Hernández LG, Slob W, White PA Empirical analysis of BMD metrics in genetic toxicology part I: in vitro analyses to provide robust potency rankings and support MOA determinations..
  8. & Cell Type-Dependent Changes in CdSe/ZnS Quantum Dot Uptake and Toxic Endpoints. Toxicological Sciences
  9. & Increased expression of ARF GTPases in prostate cancer tissue. SpringerPlus 4(1)
  10. & The clastogenicity of 4NQO is cell-type dependent and linked to cytotoxicity, length of exposure and p53 proficiency. Mutagenesis, gev069
  11. & New approaches to advance the use of genetic toxicology analyses for human health risk assessment. Toxicol. Res. 4(3), 667-676.
  12. Manshian BB, Soenen SJ, Brown A, Hondow N, Wills J, Jenkins GJ, Doak SH Genotoxic capacity of Cd/Se semiconductor quantum dots with differing surface chemistries. Mutagenesis, gev061
  13. & Quantum dot induced cellular perturbations involving varying toxicity pathways. Toxicol. Res.
  14. & Acute Dosing and p53-Deficiency Promote Cellular Sensitivity to DNA Methylating Agents. Toxicological Sciences
  15. Whiteland H, Spencer-Harty S, Morgan C, Kynaston H, Thomas DH, Bose P, Fenn N, Lewis P, Jenkins S, Doak SH A role for STEAP2 in prostate cancer progression. Clinical & Experimental Metastasis 31(8), 909-920.
  16. et. al. Chromosome Breakage Induced by the Genotoxic Agents Mitomycin C and Cytosine arabinoside is Concentration and p53 Dependent. Toxicological Sciences 140(1), 94-102.
  17. The effect of nanoparticle degradation on poly(methacrylic acid)-coated quantum dot toxicity: The importance of particle functionality assessment in toxicology. Acta Biomaterialia 10(2), 732-741.
  18. Unraveling the effects of siRNA carrier systems on cell physiology: a multiparametric approach demonstrated on dextran nanogels. Nanomedicine 9(1), 61-76.
  19. Recommendations, evaluation and validation of a semi-automated, fluorescent-based scoring protocol for micronucleus testing in human cells. Mutagenesis 29(3), 155-164.
  20. Highly sensitive covalently functionalised integrated silicon nanowire biosensor devices for detection of cancer risk biomarker. Biosensors and Bioelectronics 52, 216-224.
  21. & Automation and validation of micronucleus detection in the 3D EpiDerm  human reconstructed skin assay and correlation with 2D dose responses. Mutagenesis 29(3), 165-175.
  22. & Single-walled carbon nanotubes: differential genotoxic potential associated with physico-chemical properties. Nanotoxicology 7(2), 144
  23. Genotoxicity of nanomaterials: Refining strategies and tests for hazard identification. Environmental and Molecular Mutagenesis 54(4), 229-239.
  24. Fluorescent non-porous silica nanoparticles for long-term cell monitoring: Cytotoxicity and particle functionality. Acta Biomaterialia 9(11), 9183-9193.
  25. & The Role of Adhesion Molecules as Biomarkers for the Aggressive Prostate Cancer Phenotype. PLoS ONE 8(12), e81666
  26. & Putative prognostic epithelial-to-mesenchymal transition biomarkers for aggressive prostate cancer. Experimental and Molecular Pathology 95(2), 220-226.
  27. Influence of DNA Repair on Nonlinear Dose-Responses for Mutation. Toxicological Sciences 132(1), 87-95.
  28. & Pro-oxidant Induced DNA Damage in Human Lymphoblastoid Cells: Homeostatic Mechanisms of Genotoxic Tolerance. Toxicological Sciences 128(2), 387
  29. & Cytotoxic Effects of Gold Nanoparticles: A Multiparametric Study. ACS Nano 6(7), 5767
  30. & In vitro genotoxicity testing strategy for nanomaterials and the adaptation of current OECD guidelines. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 745(1-2), 104
  31. & In vitro genotoxicity testing strategy for nanomaterials and the adptation of curent OECD guidelines.. Mutation Research - Gen tox 745(1-2), 104-11.
  32. & Quantum Dots for Multiplexed Detection and Characterisation of Prostate Cancer Cells Using a Scanning Near-Field Optical Microscope. PLoS ONE 7(2), e31592
  33. & The role of iron redox state in the genotoxicity of ultrafine superparamagnetic iron oxide nanoparticles. Biomaterials 33(1), 163
  34. & Graphene Nano-Biosensors for Detection of Cancer Risk. Materials Science Forum 711, 246-252.
  35. & Mechanisms of cell–cell adhesion identified by immunofluorescent labelling with quantum dots: A scanning near-field optical microscopy approach. Ultramicroscopy 111(8), 1200
  36. & STEM mode in the SEM: A practical tool for nanotoxicology. Nanotoxicology 5(2), 215
  37. & Dextran coated ultrafine superparamagnetic iron oxide nanoparticles: compatibility with common fluorometric and colorimetric dyes.. Analytical Chemistry 83(10), 3778-3785.
  38. & Real-Time Reverse-Transcription Polymerase Chain Reaction: Technical Considerations for Gene Expression Analysis. 817, 251-270.
  39. & Genotoxic thresholds, mechanisms, DNA repair, and susceptibility in human populations. Toxicology 278(3), 305-310.
  40. & N-Methylpurine DNA Glycosylase Plays a Pivotal Role in the Threshold Response of Ethyl Methanesulfonate-Induced Chromosome Damage. Toxicological Sciences 119(2), 346-358.
  41. & Vinblastine and diethylsilboestrol in the in vitro mammalian cell micronucleus test (MNvit) at Swansea University UK in support of OECD draft Test Guideline 487. Mutation Research - Gen tox 702(2), 189-192.
  42. & NanoGenotoxicology: The DNA damaging potential of engineered nanomaterials. Biomaterials 30(23-24), 3891-3914.
  43. & Confounding experimental considerations in nanogenotoxicology. Mutagenesis 24(4), 285
  44. & No-observed effect levels are associated with up-regulation of MGMT following MMS Exposure. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS ?? 648(1-2), 9-14.
  45. & High resolution imaging using a novel atomic force microscope and confocal laser scanning microscope hybrid instrument: essential sample preparation aspects. Histochemistry & cell biology 130(5), 909-916.
  46. & Mechanistic Influences for Mutation Induction Curves after Exposure to DNA-Reactive Carcinogens. Cancer Research 67(8), 3904
  47. & Bone morphogenic factor gene dosage abnormalities in prostatic intraepithelial neoplasia and prostate cancer. Cancer Genetics and Cytogenetics 176(2), 161-165.
  48. & Fluorescence in-situ hybridisation on biopsies from clam ileocystoplasties and on a clam cancer. British Journal of Cancer 94(6), 891
  49. & Chromosome morphology after long-term storage investigated by scanning near-field optical microscopy. Journal of Microscopy 221(3), 177
  50. Differential expression of the MAD2, BUB1 and HSP27 genes in Barrett's oesophagus—their association with aneuploidy and neoplastic progression. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 547(1-2), 133
  51. Chromosome 4 hyperploidy represents an early genetic aberration in premalignant Barrett's oesophagus. Gut 52(5), 623-628.
  52. & Characterisation of p53 status at the gene, chromosomal and protein levels in oesophageal adenocarcinoma. British Journal of Cancer 89(9), 1729-1735.

Book Chapters

  1. & Genotoxicity and Cancer. In B Fadeel; A Pietroiusti; A Shvedova (Ed.), Adverse Effects of Engineered Nanomaterials. (pp. 243Elsevier.
  2. & Genotoxic Thresholds. In Andrew Teasdale (Ed.), Genotoxic Impurities. (pp. 169John Wiley & Sons, Ltd.