Shareen's research sits within the College ‘Biomarkers and Genes’ Theme.
Shareen is Director of the Centre for NanoHealth and she leads the In Vitro Toxicology Group, within which she heads the Nano(geno)toxicology and Prostate Cancer research programs.
Shareen’s research interests focus on the genotoxic profiles of engineered nanomaterials, the mechanisms underlying their DNA damaging potential and subsequent consequences upon human health. Her interests extend to the development of advanced 3D culture models and mechanism-based bioassays for safety assessment to reduce the need for animal testing. While her prostate cancer research focuses on understanding the molecular basis of progression to invasive, aggressive disease; with an ultimate aim of identifying a prognostic biomarker panel for improved clinical management of patients.
Shareen sits on the UK Government Committee on Mutagenicity (COM), and is the Nanomaterials Working Group Co-Leader for the International Genetic Toxicology Technical Committee (GTTC). She is also a member of the editorial boards of Mutagenesis and Mutation Research (Genetic Toxicology).
Her research career to date in the fields of genotoxicology and translational cancer research has led to the UK (2008) and European (2009) Environmental Mutagen Society “Young Scientist Awards” and the Welsh Livery Guild Merit Award (2013). Shareen is a UK and EUROTOX Registered Toxicologist, and an invited Fellow of the Royal Society of Biology (FRSB).