Specialist Topics: Biomedical Optics, Optical Spectroscopy, Nanomaterials, Sensors, Microscopy

The Meissner laboratory focuses on developing nano- and micro-structured materials and optical techniques for biomedical imaging and sensing applications. The research combines materials development with expertise in optical system design.

Materials work is anchored by microwave-assisted synthesis of nanostructures including nanoclusters, nanoparticles and nanorods. Coupled with expertise in optical spectroscopy and design, novel imaging and sensing techniques are developed through rational design.

Specific research projects include methods for the functionalization of red blood cells to serve as optical sensors and their use in long-term monitoring of blood analytes or disease state; coupling of atomic force microscopy to near-field optical techniques to enable cell surface profiling and simultaneous mechanical characterization and biochemical detection in vascular smooth muscle cells to understand cardiovascular disease; studying nanoscale energy transfer dynamics between nanoparticles as a basic tool for in vivo sensing or environmental monitoring; and hydrothermal synthesis of ZnO nanostructures for environmental and mechanical sensing.

Publications

  1. & Characterizing Nanoparticles in Biological Matrices: Tipping Points in Agglomeration State and Cellular Delivery In Vitro. ACS Nano 11(12), 11986-12000.
  2. & Multiscale benchmarking of drug delivery vectors. Nanomedicine: Nanotechnology, Biology and Medicine
  3. & Characterization of carrier erythrocytes for biosensing applications. Journal of Biomedical Optics 22(9), 091510
  4. & (2016). Brillouin spectroscopy of clotting dynamics in a model system. Presented at Proceedings of SPIE,, 96892TSPIE. doi:10.1117/12.2213595
  5. & (2016). Characterization of red blood cells (RBCs) using dual Brillouin/Raman micro-spectroscopy. Presented at Proceedings of the SPIE,, 97110M doi:10.1117/12.2213640

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Teaching

  • PH-356 Nano Bio-photonics

    Nanophotonics has the potential to revolutionise energy, telecommunication, computer and healthcare industries. Student will study the interaction of photons with nanoscale materials and the applications of this novel technology.

  • PH-M35 Nano Bio-photonics

    Nanophotonics has the potential to revolutionise energy, telecommunication, computer and healthcare industries. Student will study the interaction of photons with nanoscale materials and the applications of this novel technology.

  • PMNM02 Diagnostics and Imaging

    Nanotechnology may lead to more rapid diagnostic tests, implantable devices, point of care instruments and improved medical imaging. This module will explore the application of nanotechnology to various medical techniques, focussing on novel research devices, pre-clinical tools and emerging technology within hospitals.

Supervision

  • in vivo and in vitro sensing for disease diagnostics«br /»«br /» (current)

    Student name:
    PhD
    Other supervisor: Prof Huw Summers
  • (Tentative) Comparison of AFB and HDF (current)

    Student name:
    MSc
    Other supervisor: Dr Christopher Wright
  • Computational analysis of fluid homeostasis and flow in the lymphatic system (current)

    Student name:
    PhD
    Other supervisor: Dr Raoul Van Loon
  • Charge Generation and Transport in next generation Semiconductors (current)

    Student name:
    PhD
    Other supervisor: Dr Ardalan Armin
    Other supervisor: Prof Paul Meredith
  • Untitled (current)

    Student name:
    PhD
    Other supervisor: Dr Paolo Bertoncello
  • Excitation dynamics in solution processed disordered semiconductors (current)

    Student name:
    PhD
    Other supervisor: Dr Ardalan Armin
    Other supervisor: Prof Paul Meredith
  • Untitled (current)

    Student name:
    PhD
    Other supervisor: Dr Kevin O'Keeffe