National Research Network Fellow
Engineering
Telephone: (01792) 295253
Room: Open Plan Office - B216
Second
Engineering East
Bay Campus

My research interests lie in the broad area of computational biomechanics. I have worked on various scales all the way from mechanics of protein assemblies to that of heart valves. I am interested in the growth of biological systems and related changes in their mechanical properties and aim to provide clinical solutions to healthcare related problems by designing novel computational models based on advanced techniques like meshfree methods, multi-scale models and inverse modelling techniques.

Office: Eng East B216, Bay Campus, Swansea University

Areas of Expertise

  • Biomechanics
  • Biophysics
  • Cardiac mechanics
  • Computational mechanics
  • Meshfree methods
  • Isogeometric analysis
  • Multi-scale methods
  • Protein mechanics
  • Valve mechanics

Publications

  1. & On improving the numerical convergence of highly nonlinear elasticity problems. Computer Methods in Applied Mechanics and Engineering 337, 110-127.
  2. Determination of prestress and elastic properties of virus capsids. Physical Review E 97(3)
  3. & A multiscale active structural model of the arterial wall accounting for smooth muscle dynamics. Journal of The Royal Society Interface 15(139), 20170732
  4. An improved parameter estimation and comparison for soft tissue constitutive models containing an exponential function. Biomechanics and Modeling in Mechanobiology
  5. & In-vivo heterogeneous functional and residual strains in human aortic valve leaflets. Journal of Biomechanics 49(12), 2481-2490.

See more...

Teaching

  • EG-235 Dynamics 1

    Elements of vibrating systems; simple harmonic motion; use of complex exponential representation. One-degree-of-freedom systems; natural frequency; effect of damping; harmonic excitation; rotating out-of-balance; vibration transmission. Transient dynamics; frequency domain analysis; impulse response function. Undamped mutli-degree-of-freedom systems; eigenvalues and eigenvectors. Lagrange's equation and its physical interpretation.

Supervision

  • Analysis of Mechanisms Involved in Ventricular Assist Device (VAD) Induced Extracellular Vesicles Generation and their Cellular Effects«br /» (current)

    Student name:
    PhD
    Other supervisor: Prof Venkat Kanamarlapudi

Awards And Prizes

Date Description
2017 Selected for Welsh Crucible as a promising future research leader
2015 National Research Network (Wales) Early Career Fellowship
2014 American Heart Association Postdoctoral Fellowship
2011 Outstanding student poster award, Engg. Mechanics Institute Conference
2008 Institute Silver Medal (for best academic performance), IIT Kharagpur

Career History

Start Date End Date Position Held Location
2015 Present Wales National Research Network Research Fellow Swansea University
2012 2015 American Heart Association Postdoctoral Fellow University of Texas at Austin
2008 2012 PhD Multi-scale mechanics of protein assemblies University of California, Los Angeles
2003 2008 Undergraduate student in Aerospace Engineering Indian Institute of Technology, Kharagur

Key Grants and Projects

  • KESS II 2017 - 2020

    Analysis of mechanisms involved in shear stress induced microparticle generation and microparticle mediated effects, £54,250

  • Daiwa Foundation 2017 - 2018

    Combined experimental-computational study of cell motility, £3,000

  • Royal Society 2017 - 2018

    Mechanics of cellular monolayers - incorporating cellular biology into biomechanical models, £15,000

  • Model2Decision ESPRC Network 2017 - 2018

    Do self-expandable artificial valves offer an advantage over balloon-expandable valves in patients with calcified aortic roots?, £8,104

  • EPSRC Impact Acceleration Award 2017 - 2018

    Connecting effectively with the clinicians by streamlining the image-to-model pipeline

  • ESPRC 2017 - 2018

    Predicting cardiovascular biomechanical stiffening due to the interplay of tissue layers with focus on calcific aortic valve disease, £100,946

  • Royal Academy of Engineering 2016

    Stratification of patients at high risk of heart valve dysfunction using inverse model - Strengthening the collaboration, £4,950

  • British Council 2016

    Selected for three workshops for early career researchers sponsored by the British Council

  • National Research Network 2015 - 2018

    Modeling pre-strain and growth in biological structures, £150,000

  • American Heart Association 2014 - 2015

    Development of biomechanical identifiers for high risk of bicuspid aortic valve dysfunction, $95,704

  • Physics of viral structure and assembly 2010 - 2012

    Funded by National Science Foundation

  • Self-assembly of microtubules 2009 - 2009

    Funded by National Science Foundation