Professor Shareen H.Doak
Shareen Doak has established a research program in nanogenotoxicology and is co-lead of the In Vitro Toxicology Research Group in Swansea University’s College of Medicine. Shareen is also the Medical School’s Director of Swansea’s Centre for NanoHealth.
Her research interests focus on the DNA damaging (genotoxic) profiles of engineered nanomaterials, the underlying mechanisms responsible for this DNA damaging potential and subsequent consequences upon human health. Her interests also extend to mechanism defining genotoxic dose-responses and the impact of natural cellular protection (e.g. DNA repair) in chemical mutagenesis. Additionally, Shareen leads prostate cancer research programs within the Cancer Biomarkers Group. Her prostate cancer research focuses on understanding the molecular basis of progression to invasive, aggressive disease, with an ultimate aim of identifying a prognostic biomarker panel for improved clinical management of patients. This work is in close collaboration with colleagues in the Abertawe Bro Morgannwg University Health Board and Cardiff & Vale Health Board.
Shareen sits on the UK Committee on Mutagenicity (COM), International Genetic Toxicology Technical Committee (GTTC) and the EU Scientific Committee on Consumer Safety Working Group on Nanomaterials in Cosmetics (external expert). Shareen is a UK and EUROTOX Registered Toxicologist, and a Fellow of the Royal Society of Biology.